New plasma technology allows implants and transplants to better and more safely interact with surrounding tissue

via Wikipedia

via Wikipedia

New plasma technology allows implants and transplants to better and more safely interact with surrounding tissue

Plasma technology could improve viability of implants

Dubbed the “invisibility cloak”, engineers at the University of Sydney have developed a hydrogel that allows implants and transplants to better and more safely interact with surrounding tissue.

Published in Advanced Functional Materials, a University of Sydney team of biomedical engineers has developed a plasma technology to robustly attach hydrogels ­­– a jelly-like substance which is structurally similar to soft tissue in the human body – to polymeric materials, allowing manufactured devices to better interact with surrounding tissue.

To function optimally in the body, a manufactured implant – whether it be an artificial hip, a fabricated spinal disc or engineered tissue – must bond and interact with appropriate surrounding tissues and living cells.

When that doesn’t happen an implant may fail or, worse still, be rejected by the body. Worldwide, implant failures and rejections are a significant cost to health systems, placing large financial and health burdens on patients.

The team, which was led by School of Biomedical Engineering researchers Professor Marcela Bilek and Dr Behnam Akhavan successfully combined hydrogels including those made from silk with Teflon and polystyrene polymers.

“Despite being similar to the natural tissue of the body; in medical science hydrogels are notoriously difficult to work with as they are inherently weak and structurally unstable,” said Dr Akhavan.

“They do not easily attach to solids which means they often cannot be used in mechanically demanding applications such as in cartilage and bone tissue engineering.”

Other members of the research team included biomedical engineering PhD student Ms Rashi Walia.

“Hydrogels are highly attractive for tissue engineering because of their functional and structural similarity to human body soft tissue,” said Ms Walia.

She carried out the research in collaboration with researchers from the University of Sydney’s School of Physics and School of Chemical and Biomolecular Engineering, as well as Tufts University in Massachusetts, USA.

“Our group’s unique plasma process, recently reported in ACS Applied Materials and Interfaces, enables us to activate all surfaces of complex, porous structures, such as scaffolds, to covalently attach biomolecules and hydrogels”, said ARC Laureate and biomedical engineering academic, Professor Marcela Bilek.

“These advances enable the creation of mechanically robust complex-shaped polymeric scaffolds infused with hydrogel, bringing us a step closer to mimicking the characteristics of natural tissues within the body.

See Also

“The plasma process is carried out in a single step, generates zero waste, and does not require additional chemicals that can be harmful to the environment.”

Biomedical devices, organ implants, biosensors and tissue engineering scaffolds that are set to benefit from the new hydrogel technology.

“There are several scenarios in which this technology can be used. The gel could be loaded with a drug to release slowly over time, or it can be used to mimic structures such as bone-cartilage,” said Dr Akhavan.

“These materials are also excellent candidates for applications such as lab-on-a-chip platforms, bioreactors that mimic organs, and biomimetic constructs for tissue repair as well as antifouling coatings for surfaces submerged in marine environments.”

The research tested the material using biomolecules found in the body, which demonstrated a positive cellular response.

Dr Akhavan and the team will be progressing their area of research and will further develop the technology to combine hydrogels with non-polymeric solid materials, such as ceramics and metals.

The Latest Updates from Bing News & Google News

Go deeper with Bing News on:
Go deeper with Google Headlines on:

[google_news title=”” keyword=”hydrogel” num_posts=”5″ blurb_length=”0″ show_thumb=”left”]

Go deeper with Bing News on:
Hydrogel plasma process
  • What Is Process Improvement?

    Continual process improvement is a way to formalize efforts within your organization to root out inefficiencies and always strive to do better.

  • Structure starts to gel

    If this 'interruption' of the neutralization process is repeated, a membrane is added to the multilayer hydrogel with each cycle. Using this technique, hydrogels on the order of cubic centimetres ...

  • Promoting diabetic wound healing using microneedles

    Among these dressings, commonly used options include gauze, metal ion dressings, hydrogel dressings, and platelet-rich plasma dressings ... activities at different stages of the healing process." "In ...

  • New plasma-based treatment could help treat chronic wounds

    According to the press release, this plasma-activating hydrogel dressing employs a chemical combination ... it inhibits infection and speeds up the healing process for chronic wounds. The team ...

  • What to Know About Donating Plasma for Money

    Donating plasma is a longer process than donating blood, which is why plasma donations generally involve compensation. It takes about 90 minutes to donate plasma, and you should expect to be there ...

Go deeper with Google Headlines on:
Hydrogel plasma process

[google_news title=”” keyword=”hydrogel plasma process” num_posts=”5″ blurb_length=”0″ show_thumb=”left”]

What's Your Reaction?
Don't Like it!
I Like it!
Scroll To Top