Researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center are exploring ways to wake up the immune system so it recognizes and attacks invading cancer cells.
Tumors protect themselves by tricking the immune system into accepting everything as normal, even while cancer cells are dividing and spreading.
One pioneering approach, discussed in a review article published this week in WIREs Nanomedicine and Nanobiotechnology, uses nanoparticles to jumpstart the body’s ability to fight tumors. Nanoparticles are too small to imagine. One billion could fit on the head of a pin. This makes them stealthy enough to penetrate cancer cells with therapeutic agents such as antibodies, drugs, vaccine type viruses, or even metallic particles. Though small, nanoparticles can pack large payloads of a variety of agents that have different effects that activate and strengthen the body’s immune system response against tumors.
There is an expanding array of nanoparticle types being developed and tested for cancer therapy. They are primarily being used to package and deliver the current generation of cancer cell killing drugs and progress is being made in that effort.
“ Our lab’s approach differs from most in that we use nanoparticles to stimulate the immune system to attack tumors and there are a variety of potential ways that can be done,” said Steve Fiering, PhD, Norris Cotton Cancer Center researcher and professor of Microbiology and Immunology, and of Genetics at the Geisel School of Medicine at Dartmouth. “Perhaps the most exciting potential of nanoparticles is that although very small, they can combine multiple therapeutic agents.”
Read more . . .
The Latest on: Immune response stimulation
[google_news title=”” keyword=”Immune response stimulation” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Immune response stimulation
- Scientists at Feinstein Institutes find ultrasound neuromodulation promises to treat pulmonary hypertensionon May 9, 2024 at 3:30 am
Scientists at Feinstein Institutes find ultrasound neuromodulation promises to treat pulmonary hypertension: Manhasset, New York Thursday, May 9, 2024, 16:00 Hrs [IST] Bioelectron ...
- ENA Respiratory Receives USPTO Notice of Allowance for Key Patent Covering INNA-051, a First-in-Class Antiviral Innate Immunomodulatoron May 8, 2024 at 1:17 am
ENA Respiratory, a clinical-stage pharmaceutical company developing innate immune modulators for the prevention of complications associated with respiratory viral infections in at-risk populations, ...
- Ultrasound Neuromodulation Shows Promise to Treat Pulmonary Hypertension, Feinstein Institutes Researchon May 7, 2024 at 8:31 am
Ultrasound could one day complement or even replace drugs to treat diseases. Bioelectronic medicine scientists at The Feinstein Institutes for Medical Research used noninvasive, splenic focused ...
- Neural circuits revealed as key regulators in body's immune response, study findson May 6, 2024 at 10:18 pm
A recent study in Nature reveals how specific neural circuits within the body-brain axis regulate immune responses, highlighting potential new therapeutic approaches for immune disorders.
- Vagus Nerve Stimulation Shows Promise in Treating Infectionson May 4, 2024 at 2:00 am
Researchers have found that stimulation of the vagus nerve triggers activation of the spleen, thereby regulating antibody production. These findings highlight the potential of vagus nerve modulation ...
- New mRNA Vaccines in Development for Cancer and Infectionson May 2, 2024 at 2:22 am
Prelog also discussed personalized vaccines for cancer immunotherapy. Personalized mRNA vaccines are tailored to the patient's genetic characteristics and antigens. They could be used in cancer ...
- Scientists identify new brain circuit in mice that controls body's inflammatory reactionson May 1, 2024 at 11:50 am
The brain can direct the immune system to an unexpected degree, capable of detecting, ramping up and tamping down inflammation, shows a new study in mice.
- Columbia scientists identify new brain circuit in mice that controls body’s inflammatory reactionson May 1, 2024 at 8:03 am
Whereas the adaptive immune system remembers previous encounters with ... "In retrospect, it makes sense to have a master arbiter controlling this vital response." Previous vagus nerve stimulation ...
- Experts list anti-inflammation foods that reduce risk of cancer and dementiaon April 27, 2024 at 5:21 am
Chronic inflammation can lead to a number of serious health conditions, including cancer, heart disease, diabetes, arthritis, depression and Alzheimer's. But eating the right foods can help ...
- Common antibiotic Neosporin may shield against viral respiratory infectionson April 26, 2024 at 9:00 am
A study conducted first in mice and then in human volunteers suggests that a common antibiotic, neomycin, which is the main active ingredient in Neosporin, may help protect against viral respiratory ...
via Bing News