Scientists say they are a step closer to growing fully functioning replacement kidneys, after promising results in animals.
When transplanted into pigs and rats, the kidneys worked, passing urine just like natural ones.
Getting the urine out has been a problem for earlier prototypes, causing them to balloon under the pressure.
The Japanese team got round this by growing extra plumbing for the kidney to stop the backlog, PNAS reports.
Although still years off human trials, the research helps guide the way towards the end goal of making organs for people, say experts.
In the UK, more than 6,000 people are waiting for a kidney – but because of a shortage of donors, fewer than 3,000 transplants are carried out each year.
More than 350 people die a year, almost one a day, waiting for a transplant.
Growing new kidneys using human stem cells could solve this problem.
Scientists say they are a step closer to growing fully functioning replacement kidneys, after promising results in animals.
When transplanted into pigs and rats, the kidneys worked, passing urine just like natural ones.
Getting the urine out has been a problem for earlier prototypes, causing them to balloon under the pressure.
The Japanese team got round this by growing extra plumbing for the kidney to stop the backlog, PNAS reports.
Although still years off human trials, the research helps guide the way towards the end goal of making organs for people, say experts.
In the UK, more than 6,000 people are waiting for a kidney – but because of a shortage of donors, fewer than 3,000 transplants are carried out each year.
More than 350 people die a year, almost one a day, waiting for a transplant.
Growing new kidneys using human stem cells could solve this problem.
Read more: Lab-grown kidneys work in animals
The Latest on: Growing human organs
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The Latest on: Growing human organs
- First fetus-to-fetus transplant demonstrated in ratson April 29, 2024 at 5:00 pm
The tissue developed into functioning kidneys and produced urine.
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The fruit fly, Drosophila, has been used by scientists for more than 100 years to unravel key features of life on Earth, such as how animals respond to the sun and how the bodies of animals are ...
- UNF students create realistic 3D models of human organs in class thought to be first in nationon April 29, 2024 at 2:15 am
Working with the Mayo Clinic, the University of North Florida teaches a course called Anatomy in 3D designed to prepare for a growing medical field.
- Students create realistic 3D models of human organs in new class at UNFon April 29, 2024 at 2:15 am
Working with the Mayo Clinic, the University of North Florida teaches a course called Anatomy in 3D designed to prepare for a growing medical field.
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- Scientists regenerate neural pathways in mice with cells from ratson April 25, 2024 at 8:10 am
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CN Bio is set to expand its PhysioMimix OOC (organ on a chip) technology and research services globally following the first close of a Series B investment round which has raised $21million.
- Rat neurons repair mouse brains — and restore sense of smellon April 24, 2024 at 5:00 pm
Scientists develop hybrid mice by filling in missing cells and structures in their brains with rat stem cells.
- Experimental treatment would help patients grow new liverson April 7, 2024 at 5:00 pm
(NewsNation) — It could be the lifeline that tens of thousands of people hoping for a liver transplant: the possibility of growing their ... is unique among human organs in that it can heal ...
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