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Researchers Use Human Stem Cells to Create Light-Sensitive Retina in a Dish

Researchers Use Human Stem Cells to Create Light-Sensitive Retina in a Dish

Rod photoreceptors (in green) within a "mini retina" derived from human iPS cells in the lab. Credit: Johns Hopkins Medicine

Rod photoreceptors (in green) within a "mini retina" derived from human iPS cells in the lab. Credit: Johns Hopkins Medicine

Using a type of human stem cell, Johns Hopkins researchers say they have created a three-dimensional complement of human retinal tissue in the laboratory, which notably includes functioning photoreceptor cells capable of responding to light, the first step in the process of converting it into visual images.

“We have basically created a miniature human retina in a dish that not only has the architectural organization of the retina but also has the ability to sense light,” says study leader M. Valeria Canto-Soler, Ph.D., an assistant professor of ophthalmology at the Johns Hopkins University School of Medicine.

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