A new study at Moffitt Cancer Center could offer hope to people with melanoma, the deadliest form of skin cancer.
Researchers are investigating whether an injectable known as PV-10 can shrink tumors and reduce the spread of cancer. PV-10 is a solution developed from Rose Bengal, a water-soluble dye commonly used to stain damaged cells in the eye. Early clinical trials show PV-10 can boost immune response in melanoma tumors, as well as the blood stream.
“Various injection therapies for melanoma have been examined over the past 40 years, but few have shown the promising results we are seeing with PV-10,” said Shari Pilon-Thomas, Ph.D., assistant member of Moffitt’s Immunology Program.
In the initial study, researchers injected a single dose of PV-10 into mice with melanoma. The result was a significant reduction in the skin cancer lesions, as well as a sizable reduction in melanoma tumors that had spread to the lungs. The researchers said the dye solution appeared to produce a robust anti-tumor immune response and may be safer than existing immunological agents.
“We are currently in the middle of our first human clinical trial of PV-10 for advanced melanoma patients. In addition to monitoring the response of injected melanoma tumors, we are also measuring the boost in the anti-tumor immune cells of patients after injection,” explained Amod A. Sarnaik, M.D., assistant member of Moffitt’s Cutaneous Oncology Program.
The Latest Bing News on:
Melanoma
- UT Medical Center is first in Tennessee to offer newly FDA-approved melanoma treatmenton May 10, 2024 at 2:59 pm
The University of Tennessee Medical Center is currently the only hospital in the state to offer this type of therapy.
- Tips to determine if you might have melanomaon May 10, 2024 at 2:00 pm
As the weather gets warmer you might be looking to soak up some sun, but you should also be wary of soaking up cancer.
- Melanoma in darker skin tones: Race and sex play a role, study findson May 10, 2024 at 9:58 am
Melanoma, an aggressive form of skin cancer that accounts for 75% of all skin-cancer-related deaths, is often detected later in people with darker skin complexions—and the consequences can be ...
- Patients With Advanced, Recurrent Melanoma May Experience Lasting AEs From ICM Therapyon May 9, 2024 at 12:25 pm
A cross-sectional, mixed-methods study found that adverse effects (AEs) can occur even after 1 year of treatment with immune checkpoint modulator (ICM) therapy in patients with melanoma.
- How new immunotherapy is helping treat advanced stage 4 melanomaon May 8, 2024 at 12:48 pm
Oncologists say the single-dose immunotherapy is currently approved for those with advanced stage 4 melanoma, who have not had success with other treatments. The process works by surgically removing a ...
- These are the signs of acral melanoma to look out for on your fingernails, toenails, hands and feeton May 8, 2024 at 1:54 am
Acral Melanoma (ALM) is a specific type of melanoma that appears on the palms of the hands, the soles of the feet, or under the nails. It grows on the surface of the skin or under the nail bed before ...
- Melanoma Monday: New hope for those with an advanced form of the diseaseon May 6, 2024 at 5:24 pm
CLEVELAND — We love the sun in Northeast Ohio, but we also need to respect it. Too much of it — too many sunburns, too much time unprotected — can be dangerous and potentially lead to skin cancer.
- Pittsburgh dermatologist shares tips for preventing melanomaon May 6, 2024 at 5:12 pm
"Protect yourself -- some protective clothing, wear a hat, wear some sunscreen on things that are exposed more often than not. See your dermatologist to get at least a baseline check to assess your ...
- Woman Survives Melanoma After Having 100 Abnormal Moles Removedon May 6, 2024 at 3:57 pm
A woman shared that after her mother was diagnosed and died from melanoma, she went to the dermatologist and was also diagnosed with melanoma. She promptly had 28 moles removed at once.
- Woman diagnosed with melanoma at 28 has 100 suspicious moles removed: 'I wear my scars proudly'on May 6, 2024 at 10:12 am
Two months after her mom died from melanoma, Theresa Kurtz was stunned to receive her own skin cancer diagnosis. She had one confirmed melanoma and three severely abnormal moles that were on the verge ...
The Latest Google Headlines on:
Melanoma
[google_news title=”” keyword=”Melanoma” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
The Latest Bing News on:
Skin cancer
- Video: Tennis Legend Andy Roddick Talks Skin Cancer Surgeries and Urges Sunscreen Useon May 10, 2024 at 5:27 pm
Former tennis pro Andy Roddick is one of the most memorable players of his generation, but his legendary career left him with an unfortunate ...
- Harvard Health Publishing Q&a: Squamous Cell Skin Canceron May 10, 2024 at 2:28 pm
What is the cause and some treatment options for Squamous cell carcinoma? Answered by Dr. Howard E. Lewine M.D. Chief Medical Editor, Harvard Health Publishing · 40 years of experience · USA Squamous ...
- Protecting Against Skin Cancer in Farming and Beyondon May 10, 2024 at 11:51 am
Whether working on a farm or in a garden, everyone should be mindful of sun exposure and take precautions. The post Protecting against skin cancer in farming and beyond appeared first on AGDAILY.
- 'Cautionary Tale': Coastal Bend woman talks catching skin cancer earlyon May 10, 2024 at 8:28 am
Hilary Soderberg is bringing a new meaning to the term 'healthy glow.' The skin cancer survivor is finding a new way to help others remember to protect themselves.
- Outdoor Workers Face Skin Cancer Dangeron May 10, 2024 at 3:29 am
Folks like Murray who work outdoors are far more likely to get sunburned and tanned, putting themselves at increased risk for skin cancer, according to a new American Academy of Dermatology survey.
- Health & Wellness: Overcoming Barriers to Free Skin Cancer Screeningson May 10, 2024 at 2:09 am
John Haseney provides lessons learned from FDNY's launch of free skin cancer screenings, to give other departments a leg up on developing a program for their members.
- Scientists discover how deadly skin cancer evades the human immune systemon May 9, 2024 at 8:41 am
An international study led by Dr. Li Qi-Jing from the Agency for Science, Technology and Research (A*STAR) has revealed a mechanism by which melanoma, the most aggressive form of skin cancer, evades ...
- More than half of Americans are behind on skin cancer screenings. Here’s why you should get checkedon May 8, 2024 at 11:43 pm
May is skin cancer prevention month, and dermatologist Dr. Patricia Lucey joined WTOP to talk about screening and prevention.
- Teenage skin cancer survivor warns of sunbed riskson May 8, 2024 at 10:23 pm
A woman from Surrey who had a melanoma as a teenager is warning people about the danger of sunbeds. Georgia Edwards, 26, from Horley, underwent major surgery after being diagnosed with skin cancer ...
- Sunblock is obnoxious (but the alternative, skin cancer, is terrifying)on May 8, 2024 at 8:19 pm
No, wait, there is one thing I hate more than the feeling of sunblock: Skin cancer, which is what I would probably have if I didn’t wear sunscreen religiously. I’ve always had very fair skin. In fact, ...
The Latest Google Headlines on:
Skin cancer
[google_news title=”” keyword=”skin cancer” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]