Title: Brain magnetic resonance images showing the effects of Amino LP7 and diet on brain atrophy?
Consuming Amino LP7, a specific combination of essential amino acids, could inhibit the development of dementia, shows a study from Japan?
Protein intake is known to be vital for maintaining brain function in older individuals. Now, using a mouse model of Alzheimer’s disease, researchers have shown that the intake of a specific set of amino acids can inhibit the death of brain cells, protect the connections between them, and reduce inflammation, preserving brain function. Their research suggests that this amino acid combination called Amino LP7 can hinder the development of dementia, including Alzheimer’s disease.?
Dementia—a condition involving the extreme loss of cognitive function—is caused by a variety of disorders, including Alzheimer’s disease. According to World Health Organization estimates, approximately 10 million individuals worldwide develop dementia every year, indicating the high psychological and social impact of this condition. Dementia mainly affects older people, and so far, simple and effective strategies for preventing this condition have remained elusive.?
In a recent study published in Science Advances, Japanese researchers showed that a low protein diet can accelerate brain degeneration in mouse models of Alzheimer’s disease. More importantly, they found that Amino LP7—a supplement containing seven specific amino acids—can slow down brain degeneration and dementia development in these animals. Their work expands on previous studies, which have demonstrated the effectiveness of Amino LP7 in improving cognitive function.
Dr. Makoto Higuchi from the National Institutes for Quantum Sciences and Technology, one of the lead scientists on the study, explains, “In older individuals, low protein diets are linked to poor maintenance of brain function. Amino acids are the building blocks of proteins. So, we wanted to understand whether supplementation with essential amino acids can protect the brains of older people from dementia, and if yes, what mechanisms would contribute to this protective effect.”
First, the researchers studied how a low protein diet affects the brain in mouse models of Alzheimer’s disease, which generally demonstrate neurodegeneration and abnormal protein aggregates called “Tau” aggregates in the brain. They found that mice consuming a low protein diet not only showed accelerated brain degeneration but also had signs of poor neuronal connectivity. Interestingly, these effects were reversed after supplementation with Amino LP7, indicating that the combination of seven specific amino acids could inhibit brain damage?.
Next, the research team examined how Amino LP7 affects different signs of brain degeneration in the Alzheimer’s model. Untreated mice showed high levels of progressive brain degeneration, but Amino LP7 treatment suppressed neuronal death and thereby reduced brain degeneration, even though the Tau aggregates remained. According to Dr. Akihiko Kitamura, who also led this study, “Tau plaques in the brain are characteristic of Alzheimer’s and most treatments target them. However, we have shown that it is possible to overcome this Tau deposition and prevent brain atrophy via supplementation with Amino LP7.”
Next, to understand how Amino LP7 protects the brain, the researchers comprehensively analyzed the gene-level changes induced by Amino LP7. Their findings were quite encouraging. They observed that Amino LP7 reduces brain inflammation and also prevents kynurenine, an inflammation inducer, from entering the brain, thereby preventing inflammatory immune cells from attacking neurons. They also found that Amino LP7 reduces neuronal death and improves neuronal connectivity, improving brain function. ?
“These results suggest that essential amino acids can help maintain balance in the brain and prevent brain deterioration. Our study is the first to report that specific amino acids can hinder the development of dementia,” say Dr. Hideaki Sato and Dr. Yuhei Takado, both of whom majorly contributed to the study. “Although our study was performed in mice, it brings hope that amino acid intake could also modify the development of dementias in humans, including Alzheimer’s disease,” they add.
The study by this research group throws open several avenues for better understanding how dementias occur and how they can be prevented. Given that Amino LP7 improves brain function in older people without cognitive impairment, their findings suggest that it could also be effective in people with cognitive dysfunction.
Indeed, this patent-pending supplement could one day help millions worldwide live an improved, dementia-free life.
Original Article: A Diet of Essential Amino Acids Could Keep Dementia at Bay, Finds Study
More from: National Institutes for Quantum Sciences and Technology
The Latest Updates from Bing News & Google News
Go deeper with Bing News on:
Essential amino acids supplement
- ICMR Warns Against Protein Supplements
ICMR's new report suggests avoiding protein supplements due to potential toxins, mislabeling, and the benefits of obtaining protein from natural foods.
- The 5 best vitamins for thicker, shinier and healthier hair, according to experts
This is because "hair is non-essential tissue ... which contains vitamins and minerals for healthy hair growth, such as vitamin D, vitamin B12 and iron. Her second suggestion was the Philip Kingsley ...
- These are the best BCAA supplement brands to add to your fitness routine
Looking to add BCAAs to your supplement routine but don't know which brand to choose? Learn about the pros, cons, and essential ingredients in these top five brands. The post These are the best BCAA ...
- Why has medical panel ICMR urged people to avoid protein supplements?
In its latest dietary guidelines, ICMR emphasised the quality of protein one should consume daily and that the primary challenge should be to meet the requirements of all essential amino acids (EAA).
- Is This Ancient “Miracle Tree” Supplement The Key To Better Health?
Moringa supplements usually contain dried and powdered moringa leaves as well as extracts obtained from the seeds of the plant. In any form, the benefits of moringa remain include anti-inflammatory, ...
Go deeper with Google Headlines on:
Essential amino acids supplement
[google_news title=”” keyword=”essential amino acids supplement” num_posts=”5″ blurb_length=”0″ show_thumb=”left”]
Go deeper with Bing News on:
Amino LP7
- Top 5 Best Amino Acid Supplement for Older Adults in 2024
Amino acid additions are usually favored, predominantly by seniors, due to their beneficial impacts on muscle development and mending, enhancement of thinking abilities, and promotion of holistic ...
- Protein structure and variety
The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...
- More organic chemistry - AQA
For example, glycine is the simplest amino acid. An equation for the formation of a polypeptide which is made only from glycine is: ...
- AT-LP7
The Audio-Technica AT-LP7 turntable is a stealth work of art. From its modern, sleek design to its graceful and delicate operation, it's a complete package in a deceptively simple form factor.
- amino acid
Amino acids are small molecules that are the building blocks of proteins. Proteins serve as structural support inside the cell and they perform many vital chemical reactions. Each protein is a ...
Go deeper with Google Headlines on:
Amino LP7
[google_news title=”” keyword=”Amino LP7″ num_posts=”5″ blurb_length=”0″ show_thumb=”left”]