Developments in oral immunization delivery viewed as potential weapon to combat global health threats such as tuberculosis, AIDS and diarrheas
Scientists at The Forsyth Institute and Tufts University have succeeded in describing and validating a unique system of oral vaccine delivery using a common bacteria found in the mouth. Findings published today by Elsevier in Microbes and Infection identify Streptococcus mitis as a successful vector for oral mucosal immunization, and further research will determine its potential clinical use in tuberculosis vaccine development.
“Although injected vaccines are traditionally viewed as effective means of immunization to protect internal organs, these vaccines rarely induce strong mucosal protection in the gastrointestinal tract, respiratory tract and genitalia. In contrast, oral vaccinations have the potential to affordably, safely and effectively protect these areas, thus assisting in the fight against global health threats including diarrheas and diseases such as tuberculosis and AIDS,” said lead research Dr. Antonio Campos-Neto, a senior member of the Department of Immunology and Infectious Diseases at The Forsyth Institute. Dr. Campos-Neto is also the director for the Center for Global Infectious Disease Research, and lecturer at the Harvard School of Dental Medicine.
According to the World Health Organization, nine million people were diagnosed with tuberculosis in 2013, the latest year in which data is available, and 1.5 million people died from the disease. It is second only to HIV/AIDS in prevalence.
Read more: Scientists’ unique system of oral vaccine delivery to address global health threats
The Latest on: Oral vaccine
[google_news title=”” keyword=”oral vaccine” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Oral vaccine
- UT Health San Antonio leading $11 million study of oral vaccine for chlamydiaon May 11, 2024 at 6:45 am
The new, U.S. government-funded study will determine if the oral inoculation will also provide immunity from chlamydia in pigs and non-human primates. If that holds up, the team will file an ...
- Patralekha Chatterjee | Vaccines and trust: Need for nuanced conversationon May 10, 2024 at 11:40 am
In a polarised and election-mode India, spreading paranoia over rare side effects of the Astra-Zeneca/Covishield vaccine, willingly or unwittingly, can lead to a permanent tear in public trust ...
- Vaccine benefits outweighed riskson May 10, 2024 at 9:51 am
Virologists have pointed out that all the rare risks of a vaccine cannot be found out in the trial stage. A risk of one in one lakh or two lakh cannot be found out without luck in trials involving 30, ...
- UT Health San Antonio to lead $11 million, NIH-funded study of a first-ever oral chlamydia vaccineon May 9, 2024 at 11:08 pm
The University of Texas Health Science Center at San Antonio (UT Health San Antonio) will direct a team of researchers to investigate a novel oral vaccine for chlamydia, the ...
- UT Health San Antonio leads effort for developing oral vaccine against chlamydiaon May 9, 2024 at 1:16 pm
The study of a novel oral vaccine that could protect against chlamydia infection has been awarded approximately $11 million in National Institutes of Health funding over five years through a ...
- A new cholera vaccine will increase supply, but will it be enough to manage global outbreaks?on May 9, 2024 at 1:31 am
Along with a new manufacturing plant that will be at full capacity next year, EuBiologics will be able to produce 50 million cholera vaccine doses in 2024, and 80 million in 2025, said Lynch — most of ...
- A tailored vaccine shows promise in treating childhood eczemaon May 8, 2024 at 1:06 am
Researchers say a new "tailored" vaccine shows promise in treating eczema flares caused by a certain bacteria in children ...
- 'Hostile and discriminatory': 10th Circuit slams CU for treatment of religious vaccine exemptionson May 7, 2024 at 4:00 pm
In a fiery opinion on Tuesday, the federal appeals court based in Denver tore into a pair of COVID-19 vaccination policies the University of Colorado imposed on medical staff in late 2021, concluding ...
- As cholera cases rise worldwide, health officials sound 'concerning' alarm about vaccine shortageson May 6, 2024 at 2:24 pm
As cholera continues to surge — and as vaccines remain in short supply — experts are warning about the global risk. Here's what to know about the bacterial disease.
- Early wildlife rabies vaccine drop scheduled for Northwestern Vermont May 4on May 2, 2024 at 2:04 pm
The early distribution is in addition to the annual bait drop in August. In both rounds, rabies vaccine – in the form of a sweet-smelling oral bait that is attractive to raccoons and skunks – will be ...
via Bing News