Researchers at the Johns Hopkins Kimmel Cancer Center have developed and tested a vaccine that triggered the growth of immune cell nodules within pancreatic tumors, essentially reprogramming these intractable cancers and potentially making them vulnerable to immune-based therapies.
In their study described in the June 18 issue of Cancer Immunology Research, the Johns Hopkins team tested the vaccine in 39 people with pancreatic ductal adenocarcinomas (PDAC), the most common form of pancreatic cancer. The disease becomes resistant to standard chemotherapies and is particularly lethal, with fewer than 5 percent of patients surviving five years after their diagnosis.
PDACs do not typically trigger an immune response against the cancer cells that comprise, but with the help of a vaccine developed by Johns Hopkins researcher Elizabeth Jaffee, M.D., the scientists were able to “reprogram” tumors to include cancer-fighting immune system T cells.
Read more . . .
The Latest on: Immunotherapy vaccine
[google_news title=”” keyword=”Immunotherapy vaccine” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Immunotherapy vaccine
- Final Trial Begins for World's First Skin Cancer Vaccine, Giving Hope to Those Affectedon April 26, 2024 at 7:59 pm
As this personalized mRNA vaccine enters its final trial phase, it brings promising prospects for individuals battling melanoma.
- UK man tests personalised melanoma vaccineon April 26, 2024 at 7:04 pm
A man in England is among the first in the world to receive a personalised vaccine, which scientists hope will protect against skin cancer. Stevenage man Steve Young, 52, is one of many skin cancer ...
- U.K. Tests World-First Personalized Skin Cancer Vaccineon April 26, 2024 at 9:08 am
Customized with genetic information from a patient’s own tumor, vaccines like this could one day be used against lung, kidney, bladder and colon cancer.
- World’s 1st skin cancer vaccine enters final trial, offers personalized cureon April 26, 2024 at 8:07 am
Scientists are testing the world's first skin cancer vaccine, which has entered global trial. They aim for personalized treatment.
- Cancer vaccines could be game changing, but they’re not a one-shot solutionon April 26, 2024 at 5:49 am
These breakthroughs should give us much cause to be optimistic, but we can’t lose sight of the challenges ahead,' Iain Foulkes tells i ...
- Giving Hope: All about the world's first personalised melanoma vaccine tested in the UKon April 26, 2024 at 5:34 am
The world’s first-ever personalised mRNA vaccine for melanoma is being tested on British patients. It is a custom-built jab for people created using the specific genetic makeup of their tumour ...
- New £400,000 melanoma vaccine heralds start of 'cancer renaissance' as UK trials personalised jabs for lung, bowel, pancreas and liver tumours... but experts fear NHS can't ...on April 26, 2024 at 4:26 am
Patients have to get a new jab, alongside a course of immunotherapy, every three weeks for a year. However, experts say they are particularly excited about the potential of the vaccines to help cure ...
- ‘Real hope’ for cancer cure as personal mRNA vaccine for melanoma trialledon April 26, 2024 at 3:07 am
Excitement among patients and researchers as custom-built jabs enter phase 3 trial ...
- ‘Game-changer’ cancer jab offers hope of a cure as NHS launches trial of vaccines that ‘destroy melanoma’on April 26, 2024 at 2:33 am
THE world’s first personalised mRNA cancer jab for melanoma is being tested on British patients. The “gamechanger” mRNA jab also has the potential to stop bladder, lung and ...
- Life-saving skin cancer vaccine trialled on British patients in world firston April 26, 2024 at 1:38 am
A vaccine that could prevent skin cancer recurring is being ... There is a real hope that these will be the game-changers in immunotherapy.” The treatment, individualised neoantigen therapy, is ...
via Bing News