Their discovery may one day lead to new treatments for many common autoimmune diseases.
Researchers at the University of Georgia report in the Journal of Biological Chemistry that an enzyme known as Tumor Progression Locus 2, or Tpl2, plays a key role in directing and regulating several important components of the body’s immune system. Their discovery may one day lead to new treatments for many common autoimmune diseases.
“We know that immune dysfunction plays a serious role in a number of conditions, and we need better methods for controlling chronic inflammation,” said Wendy Watford, assistant professor of infectious diseases in UGA’s College of Veterinary Medicine and principal investigator for the study. “Our laboratory is searching for ways to disrupt the fundamental cellular processes that cause inflammation and disease.”
The human immune system is an extraordinarily complex system of cells, proteins, tissues and organs that, when everything works properly, search out and destroy disease-causing toxins and pathogens like bacteria and viruses. But sometimes it becomes confused, and the microscopic troops that normally attack only invaders turn their weapons on healthy tissues.
The resulting inflammation caused by wayward defense cells is associated with a number of autoimmune diseases and conditions, including diabetes, obesity, depression, heart disease, stroke, respiratory disease and certain cancers.
Read more . . .
The Latest on: Disease-causing inflammation
[google_news title=”” keyword=”Disease-causing inflammation” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Disease-causing inflammation
- Study finds network of inflammatory molecules may act as biomarker for risk of future cerebrovascular diseaseon May 1, 2024 at 2:00 am
A simple blood test could allow doctors to determine whether a person may be at higher risk for stroke or cognitive decline during their lifetime, according to a new UCLA Health study.
- Gene expression analyses identify potential drivers of chronic allergic inflammationon April 30, 2024 at 11:28 am
Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many ...
- 6 Subtle Ways Your Body Is Telling You That You May Have Gut Inflammationon April 30, 2024 at 9:25 am
When your gut is inflamed, you may notice that your skin flares up as well. “The gut microbiome modulates the immune system's response to inflammation, influencing the development and progression of ...
- First-ever case of brain disease linked to fentanyl inhalation reportedon April 30, 2024 at 8:33 am
Inhaling fentanyl triggered large sections of white matter in the patient’s brain to become inflamed to the point where he risked irreversible loss of brain function, or possibly death.
- Is Ozempic the New Anti-Inflammatory Wonder Drug?on April 30, 2024 at 4:00 am
Some GLP-1s are now FDA approved for chronic weight management, including Wegovy (semaglutide) and Saxenda (liraglutide), while others like Ozempic (semaglutide) are approved for type 2 diabetes but ...
- Crohn's Disease Newson April 29, 2024 at 5:00 pm
Though the two have similar symptoms, they require different ... July 17, 2023 — Chronic inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis, is on the rise worldwide.
- Lung Disease Newson April 29, 2024 at 5:00 pm
Apr. 10, 2024 — One of the molecules responsible for triggering the inflammation that causes allergic respiratory diseases, such as asthma and allergic rhinitis, has ... Discovery Into How ...
- Specialized PET scan shows chronic inflammation tied to MS progressionon April 28, 2024 at 10:00 pm
In MS, active lesions on MRI scans reflect inflammation, but there may be disease progression even when scans don’t show new activity.
- How Cancer Research Is Revolutionizing Lyme Disease Treatmenton April 28, 2024 at 4:14 pm
Fibroblast growth factor receptor inhibitors, a type of drug previously studied in the context of cancer, shows promise in reducing inflammation and cell death in brain and nerve tissue samples ...
- Fecal Transplant Shows Promise for Easing Inflammatory Bowel Disease Symptomson April 25, 2024 at 4:45 pm
For the study, scientists reviewed results from 15 clinical trials that tested fecal microbiota transplants (FMT) — when stool with healthy microorganisms is inserted into a sick patient’s digestive ...
via Bing News
