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The Transmission of Information Via Proteins Could Revolutionize Drug Discovery

The Transmission of Information Via Proteins Could Revolutionize Drug Discovery

Beta-sheet-rich proteins with minimal motifs that show correlations (Image: Nat Comm. IRB Barcelona)

Beta-sheet-rich proteins with minimal motifs that show correlations (Image: Nat Comm. IRB Barcelona)

“If we are successful, we will have discovered a gold mine for drug discovery”

A study by the scientists Xavier Salvatella and Modesto Orozco at IRB Barcelona reveals the existence of information highways that connect and correlate distant sites within a single protein.

Published in Nature Communications, the article furthers a key theoretical field for drug discovery, as it would allow the discovery of many more drug binding sites in proteins of biomedical interest.

In addition to furthering the conceptual field, Salvatella is working with proteins of biomedical interest. “We already know enough to study in parallel the pathways of proteins of biomedical interest. If we are successful, we will have discovered a gold mine for drug discovery,” affirms the scientist.

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