CRISPR-Cas9 is a revolutionary tool in part because of its versatility: created by bacteria to chew up viruses, it works equally well in human cells to do all sorts of genetic tricks, includ... Read more
Scientists in the San Francisco Bay Area identify nearly 200 potential drug targets Tuberculosis is one of the top 10 causes of death worldwide. Nearly 2 million people die every year from t... Read more
Like a great orchestra, your brain relies on the perfect coordination of many elements to function properly. And if one of those elements is out of sync, it affects the entire ensemble. In A... Read more
Li Gan, PhD, wants to find treatments to help patients with Alzheimer’s disease. Like most researchers, she’s hit a few major roadblocks. When researchers like Gan find potential new drugs,... Read more
A new way to regulate protein levels and functions could be the answer to treating devastating neurological conditions New details learned about a key cellular protein could lead to treatmen... Read more
Two chemicals improved the speed, quantity, and quality of direct cardiac reprogramming, bringing the technology one step closer to regenerating damaged hearts Scientists at the Gladstone In... Read more
In a major breakthrough, scientists at the Gladstone Institutes transformed skin cells into heart cells and brain cells using a combination of chemicals. All previous work on cellular reprog... Read more
Combining the two most powerful biological tools of the 21st century, scientists at the Gladstone Institutes have modified how the genome of induced pluripotent stem cells (iPSCs) is read fo... Read more
Finding could have implications for other autoimmune disorders, such as type I diabetes Scientists from the Gladstone Institutes have discovered a way to prevent the development of multiple... Read more
A new study from the Gladstone Institutes has revealed a way to alleviate the learning and memory deficits caused by apoE4, the most important genetic risk factor for Alzheimer’s disease, im... Read more
It did boost cognitive faculties regardless of a person’s age by the equivalent of about six IQ points PEOPLE are living longer, which is good. But old age often brings a decline in mental f... Read more
They have discovered a way to transform skin cells into mature, fully functioning liver cells that flourish on their own, even after being transplanted into laboratory animals modified to mi... Read more
Gladstone scientists reprogram skin cells into insulin-producing pancreas cells A cure for type 1 diabetes has long eluded even the top experts. Not because they do not know what must be don... Read more