‘Nanodaisies’ Deliver Drug Cocktail to Cancer Cells

Early tests of the “nanodaisy” drug delivery technique show promise against a number of cancers. Image credit: Ran Mo.
Early tests of the “nanodaisy” drug delivery technique show promise against a number of cancers. Image credit: Ran Mo.
Biomedical engineering researchers have developed daisy-shaped, nanoscale structures that are made predominantly of anti-cancer drugs and are capable of introducing a “cocktail” of multiple drugs into cancer cells.

The researchers are all part the joint biomedical engineering program at North Carolina State University and the University of North Carolina at Chapel Hill.

“We found that this technique was much better than conventional drug-delivery techniques at inhibiting the growth of lung cancer tumors in mice,” says Dr. Zhen Gu, senior author of the paper and an assistant professor in the joint biomedical engineering program. “And based on in vitro tests in nine different cell lines, the technique is also promising for use against leukemia, breast, prostate, liver, ovarian and brain cancers.”

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