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Innovation Toronto
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Massachusetts Eye and Ear

July 16, 2019

Massachusetts Eye and Ear Infirmary, known locally as Mass. Eye and Ear, is a specialty hospital providing patient care for disorders of the eye, ear, nose, throat, head and neck.

A new way to treat or prevent Alzheimer’s disease?

NIH-funded study identifies gene variant as potential drug target Defying the odds, an individual at high risk for early-onset Alzheimer’s disease remained dementia-free for many years beyond what was anticipated. A study funded in part by the National Institute on Aging (NIA), part of the National Institutes of Health, led researchers to suggest that a

A new way to treat or prevent Alzheimer’s disease?

An adhesive gel could repair injuries without surgery

An adhesive gel packed with light-activated chemicals can seal cuts or ulcers on the cornea —the clear surface of the eye — and then encourage the regeneration of corneal tissue, according to a preclinical study published online today in Science Advances. The new technology, named GelCORE (gel for corneal regeneration), could one day reduce the need for

An adhesive gel could repair injuries without surgery

Researchers invent a resistance-sensing injection device (needle) that knows where to go

Smart Needle Syringes and hollow needles—among the most feared and most commonly used tools in medical practice—have been around for more than a century. However, the precise insertion of these devices depends largely on the technique and skill of the person delivering the injection. And some anatomical regions, such as the space in the back

Researchers invent a resistance-sensing injection device (needle) that knows where to go

Could glaucoma be an autoimmune disease?

Unexpected findings show that the body’s own immune system destroys retinal cells. Glaucoma, a disease that afflicts nearly 70 million people worldwide, is something of a mystery despite its prevalence. Little is known about the origins of the disease, which damages the retina and optic nerve and can lead to blindness. A new study from

Could glaucoma be an autoimmune disease?

Hearing restored down to a whisper in deaf mice via gene therapy

In the summer of 2015, a team at Boston Children’s Hospital and Harvard Medical School reported restoring rudimentary hearing in genetically deaf mice using gene therapy.  Now the Boston Children’s research team reports restoring a much higher level of hearing — down to 25 decibels, the equivalent of a whisper — using an improved gene

Hearing restored down to a whisper in deaf mice via gene therapy

Researchers Develop Techniques to Bypass Blood-Brain Barrier, Deliver Drugs to Brain and Nervous System

Researchers at Massachusetts Eye and Ear/Harvard Medical School and Boston University have successfully shown neuroprotection in a Parkinson’s mouse model using new techniques to deliver drugs across the naturally impenetrable blood-brain barrier. Their findings, published in Neurosurgery, lend hope to patients around the world with neurological conditions that are difficult to treat due to a

Researchers Develop Techniques to Bypass Blood-Brain Barrier, Deliver Drugs to Brain and Nervous System

Researchers Regrow Human Corneas: First Known Tissue Grown from a Human Stem Cell

Limbal stem cells — identified with a new marker — could reverse a leading cause of blindness Boston researchers have identified a way to enhance regrowth of human corneal tissue to restore vision, using a molecule known as ABCB5 that acts as a marker for hard-to-find limbal stem cells. This work, a collaboration between the

Researchers Regrow Human Corneas: First Known Tissue Grown from a Human Stem Cell

Researchers Use Smart Phone Photography to Diagnose Eye Disease

Retinal (or fundus) photography is an essential part of any ophthalmology practice. Commercial fundus cameras can cost tens to hundreds of thousands of dollars, making the technology out of reach for smaller ophthalmic practices and to physicians in third-world countries. In a recent study now on line, Massachusetts Eye and Ear researchers describe the relatively

Researchers Use Smart Phone Photography to Diagnose Eye Disease

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