Researchers at King’s College London have for the first time highlighted the natural regenerative capacity of a group of stem cells that reside in the heart.
This new study shows that these cells are responsible for repairing and regenerating muscle tissue damaged by a heart attack which leads to heart failure.
The study, published today in the journal Cell, shows that if the stem cells are eliminated, the heart is unable to repair after damage. If the cardiac stem cells are replaced the heart repairs itself, leading to complete cellular, anatomical and functional heart recovery, with the heart returning to normal and pumping at a regular rate.
Also, if the cardiac stem cells are removed and re-injected, they naturally ‘home’ to and repair the damaged heart, a discovery that could lead to less-invasive treatments and even early prevention of heart failure in the future.
The study, funded by the European Commission Seventh Framework Programme (FP7), set out to establish the role of cardiac stem cells (eCSCs) by first removing the cells from the hearts of rodents with heart failure. This stopped regeneration and recovery of the heart, demonstrating the intrinsic regenerative capacity of these cells for repairing the heart in response to heart failure.
Heart failure – when the heart is unable to pump blood around the body adequately – affects more than 750,000 people in the UK, causing breathlessness and impeding daily activities. Current treatments are aimed at treating the underlying causes, such as coronary heart disease, heart attack and blood pressure through lifestyle changes, medicines and in severe cases, surgery. These treatments are sometimes successful in preventing or delaying heart failure. However, once heart failure develops the only curative treatment is heart transplantation.
By revealing this robust homing mechanism, which causes cardiac stem cells to home to and repair the heart’s damaged muscle, the findings could lead to less invasive treatments or even preventative measures aimed at maintaining or increasing the activity of the heart’s own cardiac stem cells.
The Latest Bing News on:
Heart failure
- Rheumatic Heart Disease Symptoms: 7 Warning Signs of Rheumatic Heart Disease You Should Never Ignoreon April 29, 2024 at 10:31 pm
Rheumatic heart disease isn't one-size-fits-all when it comes to symptoms. It swings between mild and severe. Read on to know more about Rheumatic Heart Disease and its warning signs.
- This Woman's Pregnancy Caused Her Heart Disease — Here's Everything You Need To Know About This Serious, Unpreventable Conditionon April 29, 2024 at 3:16 pm
"No one told me that the #1 cause of maternal mortality in the US is not only on the rise, but it is heart disease, specifically, cardiomyopathy or a weakened heart muscle. I never heard a word spoken ...
- Could vaping one time put you at a higher risk of heart failure?on April 29, 2024 at 2:38 pm
Could vaping just one time put you at higher risk of heart failure? More research is pointing to the dangers of e-cigarettes.
- Heart Failure 2024: Cutting-edge science and stimulating discussions in heart failure managementon April 29, 2024 at 12:37 pm
Cutting edge science and stimulating discussions in heart failure management are in store at Heart Failure 2024, a scientific congress of the European Society of Cardiology (ESC).
- New AI device detects heart failure through foot volumeon April 29, 2024 at 2:04 am
Installed in patients’ homes, the Heartfelt Technologies device is designed to track patients’ foot volume — or leg edema, which is a symptom associated with the onset of heart failure — each time the ...
- Gains in heart failure mortality have been erasedon April 29, 2024 at 1:47 am
Declines in heart failure-related mortality from 1999 to 2012 were entirely reversed from 2012 to 2021, according to a research letter published online April 24 in JAMA Cardiology.
- The Simple Measurement You Can Use to Calculate Your Heart Disease Risk, According to Cardiologistson April 28, 2024 at 4:25 pm
Your waist-to-hip ratio is a comparison of your waist measurement (or circumference) and your hip measurement (or circumference). High ratios show there is more fat around the middle, which has been ...
- Vaping, even once, may raise the risk of heart failure, study findson April 27, 2024 at 4:00 am
A new study indicates that people who have used a vape at any point in their lives are 19% more likely to experience heart failure compared to people who have never used them.
- Heart Failure Mortality Higher Now Than in 1999on April 26, 2024 at 12:41 pm
There needs to be a “focus on prevention of diseases and a redesign of how we deliver care,” says Marat Fudim.
- Scientific Breakthrough Could Tackle Depression and Heart Diseaseon April 25, 2024 at 1:07 am
Researchers have discovered a genetic link between depression and heart disease that could help to find new drugs to target both conditions.
The Latest Google Headlines on:
Heart failure
[google_news title=”” keyword=”Heart failure” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
The Latest Bing News on:
Prevention of heart failure
- Rheumatic Heart Disease Symptoms: 7 Warning Signs of Rheumatic Heart Disease You Should Never Ignoreon April 29, 2024 at 10:31 pm
Rheumatic heart disease isn't one-size-fits-all when it comes to symptoms. It swings between mild and severe. Read on to know more about Rheumatic Heart Disease and its warning signs.
- Heart Failure 2024 Congress Set to Address Gender Disparities and AI Integration in Cardiac Careon April 29, 2024 at 6:08 am
Join the Heart Failure 2024 Congress to explore AI in cardiac care, address gender disparities, and promote patient involvement in treatment.
- Gains in heart failure mortality have been erasedon April 29, 2024 at 1:47 am
Declines in heart failure-related mortality from 1999 to 2012 were entirely reversed from 2012 to 2021, according to a research letter published online April 24 in JAMA Cardiology.
- Vaping, even once, may raise the risk of heart failure, study findson April 27, 2024 at 4:00 am
A new study indicates that people who have used a vape at any point in their lives are 19% more likely to experience heart failure compared to people who have never used them.
- Heart Failure Mortality Higher Now Than in 1999on April 26, 2024 at 12:41 pm
There needs to be a “focus on prevention of diseases and a redesign of how we deliver care,” says Marat Fudim.
- Heart failure is the most common complication of atrial fibrillation, finds studyon April 25, 2024 at 8:00 pm
A study published in the journal The BMJ found that the lifetime risk of atrial fibrillation - a heart condition that causes an irregular and often abnormally fast heart rate - has increased from one ...
- Diabetes drug shows promise for the treatment of acute heart failureon April 25, 2024 at 2:04 pm
A multicenter study led by Vanderbilt University Medical Center (VUMC) and Lipscomb University College of Pharmacy in Nashville has identified a potential new treatment for acute heart failure, a ...
- Decline in heart failure deaths has been undone, led by people under 45on April 24, 2024 at 9:04 am
In heart failure, "the paradox is that at a time that we're seeing these increases in mortality, we also have access to better medications,” Mount Sinai Morningside's chief of cardiology said.
- New Heart Failure After AF Diagnosis Merits More Attentionon April 18, 2024 at 1:55 pm
Prevention of stroke gets highlighted by guidelines and is top-of-mind for patients, but heart failure is much more common.
- Study: Heart failure, not stroke, most common complication of atrial fibrillationon April 18, 2024 at 12:19 pm
Doctors tell patients with atrial fibrillation, which causes an irregular and often abnormally rapid heart rate, to beware of an increased risk of stroke. But the threat of heart failure should be ...
The Latest Google Headlines on:
Prevention of heart failure
[google_news title=”” keyword=”prevention of heart failure” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
