Experimental Trial Represents Promising Step Toward Universal Antidote for Snakebite

English: Indian Spectacled Cobra, Naja Naja Family, one of India's venomous snakes. (Photo credit: Wikipedia)
English: Indian Spectacled Cobra, Naja Naja Family, one of India’s venomous snakes. (Photo credit: Wikipedia)
A team of researchers, led by Dr. Matthew Lewin of the California Academy of Sciences and Dr. Stephen P. Samuel of Trinity College Dublin, Ireland has taken another promising step toward developing a universal antidote for snakebite.

Last summer, the team tested the effectiveness of a nasally administered antiparalytic drug on mice injected with high doses of Indian cobra (Naja naja) venom. Mice injected with otherwise fatal doses of venom outlived and in many cases survived after being treated with the antiparalytic agent, neostigmine. These findings support the team’s idea that providing fast, accessible, and easy-to-administer treatment can increase survival rates in victims of venomous snakebite. The results of this pilot study were recently published in the Journal of Tropical Medicine.

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