Trapping liquid chemicals in crystals form may lead to better, safer and cheaper medicines and more environmentally-friendly chemicals for the farm
A new approach for formulating the active chemical ingredients of common drugs and agricultural products has been developed by researchers in Italy, and it holds broad potential to make such products more durable, safer, cheaper, easier to manufacture and less harmful to the environment.
The technique involves taking the active chemical ingredients found in human drugs and agrochemicals, many of which are liquids, and stabilizing them with other molecules into “co-crystals,” essentially rendering them solid. Co-crystals are materials composed of two or more molecules in the same crystal lattice — conceptually you can picture a checkerboard stacked up and down and right to left with black and red pieces together.
While the idea is still in its infancy, a presentation at the 23rd Congress and General Assembly of the International Union of Crystallography, next week in Montreal will describe the first initial results of this approach, which were successful.
“The work is promising because we successfully combined into crystals a set of liquid pharmaceutical and agrochemical molecules with carefully chosen molecular partners, and thus we were able to obtain solid forms containing the liquid active molecules embedded in the ordered solid,” said Alessia Bacchi, a professor at the University of Parma in Italy who led the research.
As a general approach, co-crystallization should be able to stabilize many types of liquid chemicals into solid form, Bacchi said. Reformulating pharmaceuticals in this way could give some drugs a longer shelf life, eliminate the need for refrigeration for others, simplify some manufacturing processes, possibly reduce costs and provide patients with a pill form of a drug they could take easier than a liquid.
The Latest on: Co-Crystals
[google_news title=”” keyword=”Co-Crystals” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Co-Crystals
- Co-showrunner discusses Netflix’s ‘Dead Boy Detectives’on May 4, 2024 at 6:04 am
The darkly atmospheric, often comedic Netflix series “Dead Boy Detectives” is, in Atlanta native and co-showrunner Steve Yockey’s words, a bit like “‘The Hardy Boys’ on acid.” ...
- How to Watch Crystal Palace vs. Manchester United: Live Stream, TV Channel, Start Timeon May 4, 2024 at 3:05 am
Manchester United (sixth) and Crystal Palace (14th) square off on Monday at 3:00 PM ET, in a matchup between a pair of teams in opposite halves of the table in the Premier League. The game will ...
- Blake Lively Glistens In Crystal-Embellished Gucci Sandals at Tiffany & Co. x Pharrell Launch Eventon May 3, 2024 at 11:07 am
Blake Lively stepped into a pair of sparkling Gucci sandals when attending the launch event of Tiffany & Co.'s Titan by Pharrell Williams collection in New York City on Thursday.
- Crystal Bridges begins a weekend of wellness events centered around healthy livingon May 3, 2024 at 4:43 am
Lee's work often explores the personal impact of social justice issues, according to Crystal Bridges' website. She co-directed and co-produced "Aftershock," a 2022 film that explored the U.S. maternal ...
- Ohio State receives crystal ball prediction for 2025 four-star running backon May 2, 2024 at 2:06 pm
The 2025 recruiting cycle will be the first for Ohio State with new running back coach Carlos Locklyn who was hired away from Oregon to replace Tony Alford.
- Evereve co-founders sell Orono home for $4.5 millionon May 2, 2024 at 5:00 am
Evereve co-founders Megan and Mike Tamte have sold their home in Orono on Lake Minnetonka for $4.5 million.
- How Oliver Glasner’s Crystal Palace plan is being influenced by basketballon May 1, 2024 at 5:02 am
Watching the NBA has helped Palace boss Glasner craft his man-management and tactics – but it's just one aspect of his desire to learn ...
- CRYSTAL APPLE: Kathy Owen gives special needs students a safe place to landon April 27, 2024 at 6:14 pm
“As a co-worker, she is respectful and holds others to the same ... Kathy Owen is the model of what a Crystal Apple winner should be.” ...
- RuPaul's Drag Race star Crystal tells how they feared for their own safety after being bombarded with abuse when Laurence Fox called them a 'paedophile' on social mediaon April 26, 2024 at 2:24 am
Drag artist Crystal was sitting at home on a normal Sunday evening in 2020 when a text appeared on their phone. 'I think someone's just called you a paedophile on Twitter,' the message read.
- Attorney says Christian Co. will be location of trial in Crystal Rogers murder caseon April 25, 2024 at 12:44 pm
BARDSTOWN, Ky. (WAVE) - Attorneys overseeing the trial in the Crystal Rogers murder case have agreed to move the case out of Nelson County and a southwestern Kentucky county appears to be the top ...
via Bing News