Wellington scientists have patented a ground-breaking vaccine for asthma.
Trial results published today show the vaccine works in mice, preventing inflammation of the lungs and airways.
The vaccine is a novel way of dealing with allergies which, if successful in humans, could be expanded to other allergies and diseases.
The research, published in Nature Chemical Biology, was a collaboration between the Malaghan Institute and Victoria University’s Ferrier Research Institute.
Malaghan Institute vaccine therapy programme leader Ian Hermans said the successful mice trial results were exciting.
However, it would take at least five years of further research before the vaccine could be proven in humans.
Malaghan immune cell biology programme leader Franca Ronchese said the vaccine worked by stimulating the immune system to produce killer T-cells, which hunted down the dendritic cells that took up allergens and triggered inflammation.
“It’s like taking out the generals of the enemy’s army in order to overpower it.”
New Zealand has one of the highest asthma rates in the world, with up to one in five Kiwis affected.
A vaccine giving long-term protection would transform the lives of the 500,000 New Zealanders dependent on asthma inhalers, Ronchese said. “What we hope is that it’s not like having to take drugs for your asthma, where you have to take them all the time.
“In our mouse patients we have evidence that it can work over a long time. We can give them the allergen again and again and it still works.”
Hermans said the vaccine was also unique in that the critical components were linked to “clever chemistry”. “It’s a much more potent way of stimulating the immune response than to just grab the two components, mix them up and inject them.”
The Latest on: Asthma vaccine
[google_news title=”” keyword=”Asthma vaccine” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Asthma vaccine
- Professional Faqs: How Does Low Temperature Affect The Risk Of Infections For People With Asthma And What Precautions Should They Take?on May 9, 2024 at 2:28 pm
Low temperature can increase the risk of infections in people with asthma. Low temperature causes broncho-constriction, leading to increased mucus production and difficulty in the expiration of ...
- Eczema in children could be treated with vaccine 'within years' after major breakthroughon May 9, 2024 at 4:32 am
A jab could be the key to treating bacteria-driven flare-ups of the common condition that causes the skin to become itchy, dry and cracked, say Irish scientists ...
- TOI Health News Morning Briefing | AstraZeneca withdraws COVID vaccine, West Nile fever outbreak, pregnancy guide for summer season, fitness tips and moreon May 8, 2024 at 6:47 pm
AstraZeneca withdraws COVID vaccine worldwideAstraZeneca, the British pharmaceutical firm, is presently pulling its COVID vaccine from global circulation. This action follows months after the company ...
- Pioneering Study Suggests Vaccines Could End Eczema’s Itch for Goodon May 8, 2024 at 9:01 am
New research from a multi-disciplinary team at Trinity College Dublin suggests a “tailored vaccine” might hold the key to treating bacteria-driven flares of eczema in children. The team has taken seve ...
- Tailored vaccine could one day treat eczema in childrenon May 8, 2024 at 9:00 am
"In combination, these factors make a tailored vaccine a very attractive target as it could limit ... potentially the development of other atopic diseases, such as hayfever and asthma." The ...
- A tailored vaccine shows promise in treating childhood eczemaon May 8, 2024 at 1:06 am
Researchers say a new "tailored" vaccine shows promise in treating eczema flares caused by a certain bacteria in children ...
- A tailored vaccine could one day treat eczema in childrenon May 7, 2024 at 5:00 pm
New research suggests a 'tailored vaccine' might hold the key to treating bacteria-driven ... and potentially the development of other atopic diseases, such as hayfever and asthma." The researchers, ...
- Tailored vaccine may hold the key to treating eczema in childrenon May 7, 2024 at 5:00 pm
New research from a multi-disciplinary team at Trinity College Dublin suggests a "tailored vaccine" might hold the key to treating ... such as hayfever and asthma." The researchers, from Trinity's ...
- COVID aside, vaccines and asthma drugs deliver strong quarter for GSKon May 1, 2024 at 1:08 pm
GSK said in the first quarter of 2024, the sales of Specialty Medicines increased, driven by strong HIV and Oncology performances. However, despite increased patient demand, the company noted, ...
- GSK raises profit outlook on strong vaccine, HIV drug saleson May 1, 2024 at 3:14 am
GSK raised its full-year profit forecast on Wednesday on strong demand for its common respiratory vaccine and specialty HIV medicines, though it expects sales growth to slow in the second half.
via Bing News