A breakthrough in machine learning has also brought about a “game changer” for the science of metabolomics – and will hasten the development of diagnostic and predictive tests for Alzheimer’s, cancer, diabetes and numerous other conditions, leading to improved prevention and treatment.
University of Alberta computing science PhD graduate Siamak Ravanbakhsh published his research in the scientific journal PLOS ONE on an automated process that increases the speed and accuracy of producing a person’s metabolic profile from a sample of biofluid such as blood serum or cerebrospinal fluid using NMR spectrometry. Such a profile can provide a functional read-out of the developmental, physiological or pathological state of a biological system. This ability to quickly and accurately measure the levels of various molecules in a single sample of biofluid marks a significant advance for simple, cost-effective, predictive medical screening.
“The analogy is that we’ve been looking at the world through a keyhole and now we’re looking through a picture window,” said David Wishart, a professor of biological sciences and computing science who co-supervised the research.
This software application, dubbed Bayesil, will accelerate the creation of libraries of metabolic profiles for different biofluids that can be used to develop preventive and diagnostic screening for various diseases — in some cases months or even years before a condition is detectable by current screening methods.
Read more: Breakthrough in machine learning could revolutionize medical screening methods
The Latest on: Metabolomics
[google_news title=”” keyword=”Metabolomics” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Metabolomics
- The Effects of Exercise at the Cellular Level Revealedon May 2, 2024 at 2:00 am
Prolonged physical activity in rats results in profound changes to RNA, proteins, and metabolites in nearly all tissues, providing clues to many human health conditions.
- New biomarkers identified for predicting psychosis risk in 22q11.2 deletion syndromeon May 1, 2024 at 9:19 pm
A recent study led by UC Davis Health researchers provides new insights into the molecular changes linked to the rare genetic condition 22q11.2 deletion syndrome, or 22q.
- New Biomarkers Could Help Diagnosis of Schizophrenia in Rare Genetic Disorderon May 1, 2024 at 5:00 pm
The research was published in the journal Metabolomics. People with 22q are missing a piece of chromosome 22 that contains more than 30 genes. This loss can lead to a variety of health challenges, ...
- Study in rats helps scientists work out the effects of exercise at the cellular levelon May 1, 2024 at 8:00 am
The health benefits of exercise are well known but new research shows that the body's response to exercise is more complex and far-reaching than previously thought. In a study on rats, a team of ...
- Scientists work out the effects of exercise at the cellular levelon April 30, 2024 at 5:00 pm
The Broad project was originally conceived of by Steve Carr, senior director of Broad's Proteomics Platform; Clary Clish, senior director of Broad's Metabolomics Platform; Robert Gerszten, a senior ...
- Research reveals the importance of phytocompounds and metabolomics analysison April 30, 2024 at 1:11 pm
Inflammatory bowel disease (IBD) is a common chronic gastrointestinal disorder and current treatment strategies can cause adverse effects. Thus, there is a need to identify alternative compounds to ...
- Former MIT biologist David Sabatini, forced out after sexual harassment accusations, to lead new Boston teamon April 30, 2024 at 2:39 am
Sabatini, forced out of the Whitehead Institute after being accused of sexual harassment in 2021, is part of a new Boston-area research laboratory affiliated with the Czech scientific institute that ...
- Researchers uncover 'parallel universe' in tomato geneticson April 24, 2024 at 11:00 am
In a paper appearing in Science Advances, Michigan State University researchers have unraveled a surprising genetic mystery centered on sugars found in what gardeners know as "tomato tar." ...
- Microplastics found in food and water may spread from the gut to the brainon April 19, 2024 at 9:33 am
A new study conducted in mice found that microplastics can spread from the gut to other organs in the body, such as the brain, liver, and kidneys.
- Exploring Microbial Dark Matteron April 19, 2024 at 6:11 am
An open-source search engine helps scientists identify hundreds of microbial metabolites in a matter of seconds.
via Bing News