via University of East Anglia
Customised medicines could one day be manufactured to patients’ individual needs, with University of East Anglia (UEA) researchers investigating technology to 3D ‘print’ pills.
The team, including Dr Andy Gleadall and Prof Richard Bibb at Loughborough University, identified a new additive manufacturing method to allow the 3D printing of medicine in highly porous structures, which can be used to regulate the rate of drug release from the medicine to the body when taken orally.
Dr Sheng Qi, a Reader in Pharmaceutics at UEA’s School of Pharmacy, led the research. The project findings, ‘Effects of porosity on drug release kinetics of swellable and erodible porous pharmaceutical solid dosage forms fabricated by hot melt droplet deposition 3D printing’, are published today in the International Journal of Pharmaceutics.
Dr Qi said: “Currently our medicines are manufactured in ‘one-size-fits-all’ fashion.
“Personalised medicine uses new manufacturing technology to produce pills that have the accurate dose and drug combinations tailored to individual patients. This would allow the patients to get maximal drug benefit with minimal side effects.
“Such treatment approaches can particularly benefit elderly patients who often have to take many different types of medicines per day, and patients with complicated conditions such as cancer, mental illness and inflammatory bowel disease.”
The team’s work, Dr Qi said, is building the foundation for the technology needed in future to produce personalised medicine at the point-of-care. She said 3D printing has the unique ability to produce porous pharmaceutical solid dosage forms on-demand.
Pharmaceutical 3D printing research is a new research field that has rapidly developed in the past five years. Most commonly used 3D printing methods require the drug being processed into spaghetti-like filaments prior to 3D printing.
The team investigated a newly developed 3D printing method that can rapidly produce porous pharmaceutical tablets without the use of filaments. The results revealed that by changing the size of the pores, the speed of a drug escaping from the tablet into the body can be regulated.
Further research will be required in order to use the porosity to tailor the dose and dosing frequency (i.e. once daily or twice daily) of medicine to each patient’s needs, and use this principle to build multiple medicines into a single daily poly-pill for patients who are on a complex medicine regiment.
Original Article: PERSONALISED MEDICATIONS POSSIBLE WITH 3D PRINTING
More from: University of East Anglia | Loughborough University
The Latest Updates from Bing News & Google News
Go deeper with Bing News on:
Customised medicines
- Precision Medicine Market Poised for Rapid Growth with 12.1% CAGR Through 2032
The Precision Medicine Market is poised for substantial growth, with the global market size expected to reach USD 254 billion by 2032, up from USD 83.4 billion in 2022, reflecting a robust compound ...
- Medical ‘Digital Twins’ Will Lead the Way to Personalized Medicine
It promises to speed up a long-envisioned era of personalized medicine, which uses targeted interventions customized to each patient, to maintain or restore health. At the heart of a digital twin is a ...
- Kelly Clarkson admits she used weight loss drugs after shedding over 42 pounds
During a heartfelt interview with Whoopi Goldberg, Kelly Clarkson shared a candid revelation about her weight loss journey. At 42, Kelly, who has been the subject of much speculation regarding her ...
- Can AI build custom ‘n-of-1’ drugs faster? Maybe not yet, new case study suggests
Advocates and biotech executives hope that AI can help speed a wave of custom medicines. A new study suggests that outcome may still be years away.
- Counterfeit and Expired Medicines Sold On Sudan Markets
Sudan's National Council for Drugs and Toxins issued a warning last week regarding the unknown packaging of Amidol 500 mg tablets used as a painkiller. This warning redrew attention to the situation ...
Go deeper with Google Headlines on:
Customised medicines
[google_news title=”” keyword=”customised medicines” num_posts=”5″ blurb_length=”0″ show_thumb=”left”]
Go deeper with Bing News on:
3D printing of medicines
- An easy pill to swallow—new 3D printing research paves way for personalized medication
A new technique for 3D printing medication has enabled the printing of multiple drugs in a single tablet, paving the way for personalized pills that can deliver timed doses.
- Nashville Police Arrest Two 19-Year-Olds on Charges of Vehicle Theft, Illegal Firearms and Drug Sales
Two 19-year-olds, Bwenge and Diouf, were arrested in Nashville for vehicle theft, and illegal drug and firearms sales.
- Repeat offenders arrested; Illegal drugs and guns recovered
Two teens were arrested Thursday afternoon in connection with an ongoing investigation regarding vehicle thefts, as well as the sale of guns and illegal drugs.
- Dealer allegedly caught with $10k of drugs, instructions to 3D-print guns
A Warrnambool district drug dealer has allegedly been caught with $10,000 worth of ecstasy and instructions to create seven types of 3D-printed firearms, including handguns and shotguns.
- A Guide to 3D Printing for Healthcare, Today and Tomorrow
The technology is used by many health systems to create custom implants and models, but how will it be used in medicine as it advances?
Go deeper with Google Headlines on:
3D printing of medicines
[google_news title=”” keyword=”3D printing of medicines” num_posts=”5″ blurb_length=”0″ show_thumb=”left”]