A proof-of-concept, phase 2 trial by an international research team has found promising results for a myostatin antibody in treating the decline in muscle mass and power associated with aging.
“Myostatin is a natural protein produced within the body that inhibits muscle growth,” said Stuart Warden, a member of the research team who is also associate dean for research and associate professor in the School of Health and Rehabilitation Sciences at Indiana University-Purdue University Indianapolis. “It has been hypothesized for some time that inhibition of myostatin may allow muscle to grow, resulting in improved muscle mass and physical performance. The current study confirms these beliefs.”
In the study, injections of a myostatin antibody, made by Eli Lilly and Co., over a 24-week period resulted in an increase in lean (muscle) mass and improved performance on tasks requiring muscle power in patients older than 75 with low muscle strength, low muscle performance and a history of falling.
“This is the first study to show that myostatin antibody treatment improves performance on activities requiring muscle power,” Warden said. “‘Muscle power’ refers to the ability to generate muscle force quickly. During aging, it is lost more rapidly than muscle strength, contributing to disability, falls, reduced quality of life and, in some instances, death.”
“Myostatin antibody treatment improved muscle power in the elderly, as indicated by improvements in the ability to climb stairs, walk briskly and rise repetitively from a chair,” Warden said. “Treatment particularly benefited those who were most frail at baseline, a population who may not be receptive to conventional intervention such as resistance exercise.”
Read more: Researchers see promising results in treating age-related decline in muscle mass and power
The Latest on: Muscle power
[google_news title=”” keyword=”Muscle power” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Muscle power
- 10 Best 1960s Muscle Carson May 17, 2024 at 5:17 pm
Welcome to the 1960s, the decade of the original muscle car! These are the 10 muscle machines that really mattered.
- Ford Considers Expanding Mustang Family: Four Doors and Hybrid Power on the Horizon, But No Electric Muscle Caron May 17, 2024 at 11:13 am
Ford’s iconic Mustang muscle car could be getting a makeover. The American automaker is hinting at potential new additions to the Mustang lineup, including a four-door variant and a hybrid powertrain ...
- Dodge CEO, Muscle Car Godfather Tim Kuniskis Is Retiringon May 17, 2024 at 10:21 am
The Dodge, Ram, Jeep, Maserati, and Alfa Romeo executive retires at 57, just before the Charger Daytona EV reaches customer hands later this year.
- Power-hitting Mets prospect is minor league muscle to consider for the MLB rosteron May 17, 2024 at 5:00 am
New York Mets prospect Luke Ritter smashed 27 home runs in 2023 and looks like a more complete hitter this season. Could he be a candidate for the MLB roster?
- Penske Flexes Muscle on ‘Fast Friday’ as Qualifying Loomson May 16, 2024 at 5:00 pm
Penske teammates Josef Newgarden, Scott McLaughlin and Will Power were the three fastest drivers during simulated qualifying runs in practice Friday for the 108th edition of “The Greatest Spectacle in ...
- 9 Of The Best Engines Ever Put In A Mopar Muscle Caron May 15, 2024 at 3:30 pm
Mopar has been producing iconic powerplants for decades, from the 426 Hemi to the Hellcat V8. Here are some of its best engines that ended up in a muscle car.
- 10 Of The Best Engines Ever Put In A Ford Muscle Caron May 12, 2024 at 9:30 am
Ford has made some of the most iconic muscle cars in automotive history, and under their hoods sit many similarly iconic engines. Here are our favorites.
- 2023 Dodge Challenger Demon 170: The Greatest Muscle Car Ever?on May 9, 2024 at 3:00 am
Dodge Challenger SRT Demon 170 the greatest muscle car in the history of muscle cars? Well, it's certainly the quickest and most powerful ...
- The Best Creatine Supplements for Men for Muscle Growth and Enhanced Recoveryon October 15, 2021 at 9:37 am
Men’s Journal aims to feature only the best products and services. If you buy something via one of our links, we may earn a commission. The products featured here have been independently reviewed.
- 76 Eccentric Exercises For Achilles Tendinopathy Do Not Fully Resolve Plantarflexor Muscle Power Deficitson June 4, 2021 at 12:09 am
Introduction Our previous work has shown a clear clinical and statistical significant difference in Plantarflexor power between healthy controls and participants with Achilles tendinopathy (AT), p ≤ 0 ...
via Bing News