A small study at Boston Children’s Hospital may lead to a breakthrough treatment for kids with life-threatening peanut allergies.
Researchers there combined an FDA-approved allergy drug, Xolair, with increased exposure to peanuts. Xolair is made by Swiss pharmaceutical company Roche AG’s Genentech unit.
The pilot included just 13 children, and the results were dramatic: Just three allergic reactions requiring intervention with epinephrine during the year-long study. Finding a first-ever treatment for peanut allergies is an important health care goal and a huge market opportunity. To underscore that point, one of the chief researchers in the study, Dr. Dale Umetsu, has now been hired away by Genentech to be its principal medical director.
The study was based on a 2010 protocol for desensitizing children to milk allergies, also developed by Umetsu and other Children’s researchers. Participants received allergy drug injections for three months. After this pretreatment, all 13 subjects tolerated an initial 11 desensitization doses, including the maximum dose of about two peanuts, and required minimal or no rescue therapy.
Then for eight weeks, subjects tolerated doses of about 16 peanuts, and after that the drug injections were discontinued. At the end of the yearlong study, 12 of the 13 participants could tolerate about 20 peanuts per day without receiving much additional treatment beyond an occasional antihistamine.
Go deeper with Bing News on:
Peanut allergy
- Toothpaste for peanut allergies!
You could call five-year-old Kaleb Billeter somewhat of a Lego expert. Not much worries him, but his mother, on the other hand, worries a lot.
- Antibody Levels Can Predict Children Likely To Outgrow Peanut Allergies
Changes in antibody levels over time can predict which children are likely to outgrow their peanut allergy, according to a new study.
- How antibody levels can predict which children will outgrow their peanut allergy
Australian researchers have discovered how changes in antibody levels over time can predict which children are likely to outgrow their peanut allergy.
- Yes, adults can develop food allergies. Here are 4 types you need to know about
It's hard to get accurate figures on adult food allergy prevalence. The Australian National Allergy Council reports one in 50 adults have food allergies. But a US survey suggested as many as one in ...
- Ingredient Notice (Milk, Peanut and Soy): McDonald’s USA
McDonald’s wants to make customers with milk, soy, or peanut allergies aware of these allergens in the Grandma McFlurry ...
Go deeper with Google Headlines on:
Peanut allergy
[google_news title=”” keyword=”Peanut allergy” num_posts=”5″ blurb_length=”0″ show_thumb=”left”]
Go deeper with Bing News on:
Peanut allergies
- Toothpaste for peanut allergies!
You could call five-year-old Kaleb Billeter somewhat of a Lego expert. Not much worries him, but his mother, on the other hand, worries a lot.
- Longitudinal antibody changes key to identifying peanut allergy resolution in kids
Australian researchers have discovered how changes in antibody levels over time can predict which children are likely to outgrow their peanut allergy.
- Antibody Levels Can Predict Children Likely To Outgrow Peanut Allergies
Changes in antibody levels over time can predict which children are likely to outgrow their peanut allergy, according to a new study.
- Yes, adults can develop food allergies. Here are 4 types you need to know about
It's hard to get accurate figures on adult food allergy prevalence. The Australian National Allergy Council reports one in 50 adults have food allergies. But a US survey suggested as many as one in ...
- Ingredient Notice (Milk, Peanut and Soy): McDonald’s USA
McDonald’s wants to make customers with milk, soy, or peanut allergies aware of these allergens in the Grandma McFlurry ...
Go deeper with Google Headlines on:
Peanut allergies
[google_news title=”” keyword=”peanut allergies” num_posts=”5″ blurb_length=”0″ show_thumb=”left”]