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Strategy proposed for preventing diseases of aging

Strategy proposed for preventing diseases of aging

NATIONAL CANCER INSTITUTE Aging experts urge more focus on disease prevention to promote a long and healthy lifespan. Strategies include a healthy diet, exercise and possibly manipulating molecular pathways that slow aging.

NATIONAL CANCER INSTITUTE Aging experts urge more focus on disease prevention to promote a long and healthy lifespan. Strategies include a healthy diet, exercise and possibly manipulating molecular pathways that slow aging.

Medicine focuses almost entirely on fighting chronic diseases in a piecemeal fashion as symptoms develop. Instead, more efforts should be directed to promoting interventions that have the potential to prevent multiple chronic diseases and extend healthy lifespans.

Researchers writing in the journal Nature say that by treating the metabolic and molecular causes of human aging, it may be possible to help people stay healthy into their 70s and 80s.

In a commentary published July 24 in Nature, a trio of aging experts calls for moving forward with preclinical and clinical strategies that have been shown to delay aging in animals. In addition to promoting a healthy diet and regular exercise, these strategies include slowing the metabolic and molecular causes of human aging, such as the incremental accumulation of cellular damage that occurs over time.

The researchers, at Washington University School of Medicine in St. Louis, Brescia University in Italy, the Buck Institute for Aging and Research and the Longevity Institute at the University of Southern California, write that economic incentives in biomedical research and health care reward treating disease more than promoting good health.

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