Like a self-assembling ‘Lego Death Star’, says lead researcher
Researchers have developed a simple and versatile method for making artificial anti-cancer molecules that mimic the properties of one of the body’s natural defence systems.
The chemists, led by Professor Peter Scott at the University of Warwick, UK, have been able to produce molecules that have a similar structure to peptides which are naturally produced in the body to fight cancer and infection.
Published in Nature Chemistry, the molecules produced in the research have proved effective against colon cancer cells in laboratory tests, in collaboration with Roger Phillips at the Institute for Cancer Therapeutics, Bradford, UK.
Artificial peptides had previously been difficult and prohibitively expensive to manufacture in large quantities, but the new process takes only minutes and does not require costly equipment. Also, traditional peptides that are administered as drugs are quickly neutralised by the body’s biochemical defences before they can do their job.
Reaad more . . .
The Latest on: Anti-cancer molecules
[google_news title=”” keyword=”Anti-cancer molecules” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Anti-cancer molecules
- Four of the best superfoods to help reduce inflammationon April 30, 2024 at 11:04 pm
When inflammation becomes chronic and long-lasting though, it can have a negative effect on our health, contributing to diseases like heart disease, cancer, stroke and diabetes ... These ...
- Unlocking the immune system: cGAS-STING pathway offers new hope for cancer breakthroughson April 30, 2024 at 6:57 am
A groundbreaking study has recognized the cGAS-STING signaling pathway as a formidable ally in the immune system's battle against cancer. This ...
- Cancer Drugs: Strategies For Patenting Antibody-Drug Conjugate Inventionson April 29, 2024 at 5:00 pm
While ADCs are based on the seemingly simple idea of using the targeting ability of antibodies to deliver more toxically potent drugs to specific cancer cells, ADCs are complicated molecules that ...
- Liver cells effectively serve as immune checkpoint regulating anti-cancer immunityon April 22, 2024 at 1:03 pm
Liver inflammation, a common side-effect of cancers elsewhere in the body, has long been associated with worse cancer outcomes and more recently associated with poor response to immunotherapy.
- Uses and Benefits of Aloeon April 22, 2024 at 9:00 am
Aloe is a plant species with many medicinal and therapeutic uses. There are over 500 species, including aloe vera.
- CSHL’s Josh Homer produces chemical compounds with potentialon April 22, 2024 at 8:51 am
Homer found that eight of the microtubule targeting agents were more potent than colchicine against HCT-15. This cancer cell line, he explained, is known to have upregulated efflux, which is a major ...
- Study finds how liver inflammation associated with poor cancer outcomeson April 19, 2024 at 10:10 am
Liver inflammation, a typical side effect of malignancies elsewhere in the body, has long been associated with poor cancer outcomes and, more recently, with poor response to immunotherapy. A team of ...
- Liver-Based Signaling Protects Tumors by Restraining Anticancer Immune Cellson April 18, 2024 at 5:00 pm
In 2021, researchers from the Beatty Lab observed that systemic inflammation, involving many of the same molecules ... of pancreatic cancer, measuring the amount of T-cell infiltration in pancreatic ...
- Study of cancer-induced liver inflammation finds a promising therapeutic targeton April 18, 2024 at 5:00 pm
"Our findings show that liver cells—with their release of SAA proteins—effectively serve as an immune checkpoint regulating anti-cancer immunity ... many of the same molecules implicated ...
- Liver-Based Signaling Protects Tumors by Restraining Anticancer Immune Cellson April 18, 2024 at 5:00 pm
The scientists looked at mouse models of pancreatic cancer, measuring the amount of T-cell infiltration in pancreatic tumors—a basic indicator of anti-tumor immune activity. They found that mice ...
via Bing News