Testing for health conditions usually involves needles, X-rays and other invasive or uncomfortable measures. To make diagnostics less burdensome for patients, scientists are developing alternatives, looking for disease markers in urine — and even spit.
Now a study, appearing in ACS’ Journal of Proteome Research, demonstrates for the first time that individuals may have saliva “fingerprints.” The finding suggests that identifying changes in these baseline fingerprints could someday be a reliable way to detect disease.
In the search for non-invasive and less stress-inducing ways to detect disease, much effort has focused on urine testing. Individuals’ urine samples have specific metabolic signatures that can become altered when a person develops a health problem. But compounds in urine can also vary depending on factors such as diet and environment. Saliva has similar potential as an easy-to-access fluid that changes in response to health conditions, but could be less affected by diet and the environment. Paola Turano, Kurt Zatloukal and colleagues wanted to investigate how reliable this route might be.
The researchers sampled saliva and urine from 23 healthy volunteers multiple times a day over 10 days. The molecular signatures of saliva and urine were distinct and consistent for each participant. But profiles from spit samples changed less due to dietary variations than those from urine. Although longer-term research would be needed, this initial work on saliva fingerprints suggests that they could be useful in searching for signs of disease, say the researchers.
The Latest on: Diagnosing disease
[google_news title=”” keyword=”Diagnosing disease” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Diagnosing disease
- Jamie-Lynn Sigler Says the ‘Sopranos’ Set Physician Told Her Not to Disclose MS Diagnosison April 26, 2024 at 9:11 pm
The actress, who played Meadow Soprano on the hit HBO series, was diagnosed at 20-years-old but didn't disclose her medical issues publicly until 2016.
- 'There's life with Parkinson's' says Nottingham nurse diagnosed with disease aged 35on April 26, 2024 at 8:00 pm
The Queen's Medical Centre operating theatre nurse said her wait for answers had left her wanting to 'curl up into a ball' ...
- ‘Sopranos’ Star On James Gandolfini’s Caring Reaction To Her MS Diagnosison April 26, 2024 at 6:11 pm
Sopranos” star Jamie-Lynn Sigler says James Gandolfini was the first person on the show to learn of her multiple sclerosis diagnosis. She recalls his heartfelt reaction to her revelation.
- Embiid's diagnosis draws new attention to Bell's palsyon April 26, 2024 at 2:15 pm
Philadelphia 76ers All-Star center Joel Embiid has been diagnosed with Bell's palsy. A facial nerve gets inflamed or injured and suddenly muscles on one side of the face become weak or paralyzed.
- Missy Elliott's Graves' Disease Caused 'Extreme' Weight Loss: Here's What She's Shared About Her Conditionon April 26, 2024 at 9:41 am
Symptoms include weight loss (despite having an increased appetite), a rapid or irregular heartbeat, fatigue, shaky hands, and trouble tolerating heat, the NIDDK says. Missy revealed that she was ...
- Ticks on Long Island: Disease-carrying critters now a year-round problemon April 26, 2024 at 8:57 am
Long Island is one of the epicenters for Lyme disease. Education and prevention are keys to avoiding tick bites and infections.
- What It’s Like to Live With Neurologic Lyme Disease: A Patient Perspectiveon April 26, 2024 at 6:24 am
Diagnosing patients with neurologic Lyme disease can take upwards of 2 years, which Maria Arini Lopez discovered first-hand in the spring of 2021.
- Kadyrov diagnosed with brain disease in addition to pancreatic necrosis - mediaon April 25, 2024 at 6:01 pm
The head of Chechnya, Ramzan Kadyrov, has been diagnosed with a new disease that will affect his entire life. Kadyrov also suffers from pancreatic necrosis, ...
- Diagnosis of rare eye diseases: Uveitis experts provide an overview of an underestimated imaging techniqueon April 25, 2024 at 6:51 am
Uveitis is a rare inflammatory eye disease. Posterior and panuveitis in particular are associated with a poor prognosis and a protracted course of the disease. Diagnosis and monitoring can be ...
- I Blamed WFH For My Weight Changes and Mood. Then I Was Diagnosed With Cushing Disease.on April 24, 2024 at 10:35 pm
Laurie Riihimaki experienced unexplainable weight gain, depression, fatigue, and insomnia for three years before being diagnosed with Cushing disease.
via Bing News