Max Planck scientists have used silk from the tasar silkworm as a scaffold for heart tissue.
Damaged human heart muscle cannot be regenerated. Scar tissue grows in place of the damaged muscle cells. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim are seeking to restore complete cardiac function with the help of artificial cardiac tissue. They have succeeded in loading cardiac muscle cells onto a three-dimensional scaffold, created using the silk produced by a tropical silkworm.
Of all the body’s organs, the human heart is probably the one most primed for performance and efficiency. Decade after decade, it continues to pump blood around our bodies. However, this performance optimisation comes at a high price: over the course of evolution, almost all of the body’s own regeneration mechanisms in the heart have become deactivated. As a result, a heart attack is a very serious event for patients; dead cardiac cells are irretrievably lost. The consequence of this is a permanent deterioration in the heart’s pumping power and in the patient’s quality of life.
In their attempt to develop a treatment for the repair of cardiac tissue, scientists are pursuing the aim of growing replacement tissue in the laboratory, which could then be used to produce replacement patches for the repair of damaged cardiac muscle. The reconstruction of a three-dimensional structure poses a challenge here. Experiments have already been carried out with many different materials that could provide a scaffold substance for the loading of cardiac muscle cells.
“Whether natural or artificial in origin, all of the tested fibres had serious disadvantages,” says Felix Engel, Research Group Leader at the Max Planck Institute for Heart and Lung Research in Bad Nauheim. “They were either too brittle, were attacked by the immune system or did not enable the heart muscle cells to adhere correctly to the fibres.” However, the scientists have now found a possible solution in Kharagpur, India.
The Latest Bing News on:
Artificial cardiac tissue
- AI technology giving heart failure patients better care, more access to doctorson May 9, 2024 at 3:26 pm
Revolutionary technology powered by artificial intelligence is giving heart failure patients better care and more access to doctors and the therapies that they need.
- New fluidic system advances development of artificial blood vessels and biomedicine applicationson May 9, 2024 at 7:05 am
Nature consistently inspires engineering applications. Recently, a group of researchers from the Faculty of Engineering at the University of Hong Kong (HKU) drew new inspiration from the vascular ...
- J&J's Biosense Webster brings AI to its heart-mapping Carto 3 systemon May 8, 2024 at 3:15 am
Johnson & Johnson MedTech’s Biosense Webster division is rolling out a new version of its heart-mapping system that the company says marks its first to employ artificial intelligence capabilities. The ...
- Exo’s FDA Cleared Cardiac & Lung AI Now on Iris Handheld Ultrasoundon April 22, 2024 at 4:59 pm
Exo, a medical imaging software and device company, has announced its FDA-cleared cardiac and lung artificial intelligence (AI) applications are now available on Exo Iris, the company’s handheld ...
- The first blueprint for building an artificial ovaryon April 16, 2024 at 5:01 pm
With greater insight into the developmental process of follicles, the team is hopeful that they will be able to trigger cells into maturity and produce optimized artificial ovarian tissue, which can ...
- Artificial heart boy recoverson April 7, 2024 at 5:00 pm
The youngest ever person to receive an artificial heart implant has had it removed when his own heart started working again. Sixteen-year-old Jamie Darney from Port Talbot in south Wales was given ...
- Biomedical engineers use AI to build new tool for studying and diagnosing heart functionon April 7, 2024 at 5:00 pm
A promising way to study disease and test new drugs is to use cellular and engineered tissue models ... way to study heart function, using a methodology based on artificial intelligence (AI ...
- Artificial Heart Valveon April 3, 2024 at 5:00 pm
A version of this article appears in the November 4, 1961 issue of Science News. Love our Health & Medicine stories? Our coverage would not be possible without the generous support of subscribers ...
- Electrospinning Artificial Heart Valveson March 29, 2024 at 7:14 am
To explore the uses of this material, [Riley] chose to make an artificial heart valve. This required a 3D-printed framework with three prongs, painted with conductive paint. He tried a few ...
The Latest Google Headlines on:
Artificial cardiac tissue
[google_news title=”” keyword=”artificial cardiac tissue” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
The Latest Bing News on:
Replacement heart tissue
- ASGCT 2024: Charles Murry Doesn’t Skip a Beat in Cardiac Arrhythmia Talk during the Presidential Symposiumon May 9, 2024 at 2:27 pm
Charles Murry, PhD, presented years of work during the Presidential Symposium at ASGCT on Tuesday. He shared his research story to better inform cardiac regeneration research and therapy options.
- Edwards launches Sapien 3 Ultra Resilia TAVR in Europeon May 9, 2024 at 6:28 am
Sapien 3 Ultra Resilia is the only transcatheter aortic valve replacement (TAVR) system incorporating the company’s Resilia tissue technology. Edwards designed the Resilia technology to extend the ...
- EDWARDS LAUNCHES THE SAPIEN 3 ULTRA RESILIA VALVE WITH TECHNOLOGY TO ENHANCE DURABILITYon May 8, 2024 at 5:00 pm
J Heart Valve Dis. 2015 Jan ... Seven-Year Outcomes Following Aortic Valve Replacement with a Novel Tissue Bioprosthesis. J Thorac Cardiovasc Surg. 2023 Sep 29:S0022-5223(23)00873-5. § Stinis CT, ...
- How to Avoid Open-Heart Surgery if You Have Leaky Tricuspid Valveon May 8, 2024 at 4:25 pm
UC San Francisco interventional cardiologists and interventional echocardiographers recently performed the health system’s first commercial transcatheter tricuspid valve replacement procedure using ...
- Edwards Launches the SAPIEN 3 Ultra RESILIA Valve in Europe With Technology to Enhance Durabilityon May 8, 2024 at 4:21 pm
Edwards Lifesciences today announced the European launch of the SAPIEN 3 Ultra RESILIA valve, the only transcatheter aortic heart valve to incorporate the company’s breakthrough RESILIA tissue ...
- Capstan Medical’s cardiac surgical robotics mission: ‘Not for the faint of heart’on May 8, 2024 at 4:18 pm
Capstan Medical CEO Maggie Nixon says the surgical robotics developer is "driving hard" toward its first-in-human mitral valve replacement.
- Insights into India’s growing heart health crisison May 8, 2024 at 11:37 am
Aortic stenosis with a high mortality rate is a significant cardiovascular concern. Non-surgical aortic valve replacement emerges as a game-changer Aortic stenosis stands as one of India’s most ...
- Heart Disease Newson May 5, 2024 at 5:00 pm
Why Can Zebrafish Regenerate Damaged Heart Tissue, While Other Fish Species Cannot? Apr. 18, 2024 — A heart attack will leave a permanent scar on a human heart, yet other animals, including ...
- NCH Health: Cardiologist performs first transcatheter tricuspid valve replacement in Fla.on May 3, 2024 at 9:02 am
I am excited to announce that the NCH Rooney Heart Institute recently performed a groundbreaking procedure for patients with valvular heart disease.
- Fat Replacement for Heart Health? If Only It Were That Simpleon May 3, 2024 at 12:38 am
The human body is the most complex machine on the face of the Earth. Like any machine, it requires an input of fuel to function along with a variety of chemicals for proper maintenance. In this case, ...
The Latest Google Headlines on:
Replacement heart tissue
[google_news title=”” keyword=”replacement heart tissue” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]