Cheap diclofenac has anti-cancer properties
Diclofenac, a common painkiller, has significant anti-cancer properties, according to researchers. Like other drugs examined by the ReDO project, diclofenac is cheap and readily accessible — and as it’s already present in many medicine cabinets, it has been carefully tested.
The Repurposing Drugs in Oncology (ReDO) project, an international collaboration between the Anticancer Fund, Belgium, and US based GlobalCures, finds that existing and widely-used non-cancer drugs may represent a relatively untapped source of novel therapies for cancer.
Their investigation into diclofenac has been published in the open-access journal ecancermedicalscience.
Like other drugs examined by the ReDO project, diclofenac is cheap and readily accessible — and as it’s already present in many medicine cabinets, it has been carefully tested.
Diclofenac is a well-known and widely used non-steroidal anti-inflammatory drug (NSAID) used to treat pain in conditions such as rheumatoid arthritis, as well as migraine, fever, acute gout and post-operative pain. It is available as a generic medication and is cost-effective.
NSAIDs have shown promise in cancer prevention, but there is now emerging evidence that such drugs may be useful in actually treating cancer. For example, diclofenac taken in combination with other treatments, such as chemotherapy and radiotherapy, may improve their effectiveness.
The ReDO researchers examined the literature and believe that there is enough evidence to start clinical trials on the use of diclofenac in cancer treatment.
Read more: Painkiller tapped to become future cancer-killer
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