Karolinska Institutet

Karolinska Institutet (often translated from Swedish into English as the Karolinska Institute, the -et being a definite article, and in older texts often as the Royal Caroline Institute) is a medical university in Solna within the Stockholm urban area, Sweden, and one of Europe’s largest and most prestigious medical universities.

A new method to detect whether or not bacteria respond to antibiotics within minutes

Therapy delivered over the internet really can help people with anger and aggression issues

Cost-effective surveillance of the global spread of new SARS-CoV-2 variants

A new method for fast, cheap, yet accurate testing for COVID-19

A gene-targeting antiviral agent against COVID-19

Identified: Proteins that protect against joint inflammation

An inexpensive drug may be used to counteract treatment resistance in acute myeloid leukemia

A promising new treatment for neuroblastoma found by a smart algorithm

Could the abnormal expression of genes impact psychopathy?

The expression of many genes that have previously been associated with autism is abnormal also in violent psychopathy, a new study shows. The researchers used stem cell technology to analyse the expression of genes and proteins in the brain cells of psychopathic violent offenders. Published in Molecular Psychiatry, the findings may open up new avenues for

Could the abnormal expression of genes impact psychopathy?

Viruses can facilitate the formation of plaques characteristic of neurodegenerative diseases such as Alzheimer’s disease

New research from Stockholm University and Karolinska Institutet shows that viruses interact with proteins in the biological fluids of their host which results in a layer of proteins on the viral surface. This coat of proteins makes the virus more infectious and facilitates the formation of plaques characteristic of neurodegenerative diseases such as Alzheimer’s disease.

Viruses can facilitate the formation of plaques characteristic of neurodegenerative diseases such as Alzheimer’s disease

A new inflammation inhibitor has been discovered

A multidisciplinary team of researchers led from Karolinska Institutet in Sweden have developed an anti-inflammatory drug molecule with a new mechanism of action. By inhibiting a certain protein, the researchers were able to reduce the signals that trigger an inflammation. The study is published in Science and was done in collaboration with the University of

A new inflammation inhibitor has been discovered

Stronger muscles in old age with stem cells?

As we grow older, our muscular function declines. A new study by researchers at Karolinska Institutet shows how an unexpectedly high number of mutations in the stem cells of muscles impair cell regeneration. This discovery may result in new medication to build stronger muscles even when in old age. The study is published in Nature Communications. It

Stronger muscles in old age with stem cells?

Conducting plastics can be used to trick the metabolism of pathogenic bacteria

Conducting plastics found in smartphone screens can be used to trick the metabolism of pathogenic bacteria, report scientists at Karolinska Institutet in the scientific journal npj Biofilms and Microbiomes. By adding or removing electrons from the plastic surface, bacteria may be tricked into growing more or less. The method may find widespread use in preventing bacterial

Conducting plastics can be used to trick the metabolism of pathogenic bacteria

Kilometer long threads of artificial spider silk

Being able to produce artificial spider silk has long been a dream of many scientists, but all attempts have until now involved harsh chemicals and have resulted in fibers of limited use. Now, a team of researchers from the Swedish University of Agricultural Sciences and Karolinska Institutet has, step by step, developed a method that

Kilometer long threads of artificial spider silk

Artifical neuron mimicks function of human cells

Scientists at Sweden’s Karolinska Institutet have managed to build a fully functional neuron by using organic bioelectronics. This artificial neuron contain no ‘living’ parts, but is capable of mimicking the function of a human nerve cell and communicate in the same way as our own neurons do. Neurons are isolated from each other and communicate

Artifical neuron mimicks function of human cells

Ion pump gives the body its own pain alleviation

A small ion pump in organic electronics is giving new hope to people suffering from severe nerve pain. Researchers at Linköping University (LiU) and Karolinska Institutet (KI) are the first in the world with technology that can stop pain impulses in living, freely moving rats using the body’s own pain relief signals. The results of

Ion pump gives the body its own pain alleviation

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Karolinska Institutet Research

New technology changes how proteins in individual cells are studied
Karolinska Institutet. "No one else has previously reported a similar technology, which is why this is so unique," says Brodin. The next step is to use molecular pixelation in research on cancer, the ...
Karolinska Development’s portfolio company Umecrine Cognition initiates second part of clinical phase 1a/2 study in PBC
Story continues Karolinska Development has access to world-class medical innovations at the Karolinska Institutet and other leading universities and research institutes in the Nordic region. The ...
Combination therapy shown to shrink tumours
A collaborative team effort led by the Tumor Immunotherapy and Microenvironment (TIME) group at the Luxembourg Institute of Health, along with Sprint Bioscience and Karolinska Institutet (Sweden) ...
A New Way To Treat Obesity? Scientists Discover Surprising Effects of New Drug
Researchers at Karolinska Institute have potentially discovered a novel method to combat obesity and associated conditions by focusing on the mitochondria, the powerhouses of the cell. A study publish ...
Early genetic development of the brain mapped
An international research team led by Karolinska Institutet has mapped the early genetic development of the brain and can now present an atlas of embryonic development between weeks six and 13. "This ...

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Karolinska Institutet Discovery

A New Way To Treat Obesity? Scientists Discover Surprising Effects of New Drug
Researchers at Karolinska Institute have potentially discovered a novel method to combat obesity and associated conditions by focusing on the mitochondria, the powerhouses of the cell. A study publish ...
Leprosy drug may be effective in Huntington's disease, study suggests
A preclinical study from Karolinska Institutet offers hope for treating severe neurodegenerative diseases with an existing drug. The study suggests that the leprosy drug clofazimine may be effective ...
Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice
Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' powerhouses, the mitochondria.
New drug candidate reverses obesity in mice
Researchers at Karolinska Institutet may have found a new way ... Therapeutics Inc. Three of the coauthors are employees of Lead Discovery Center and are listed as co-inventors on a patent ...
Multi-omics approach powers Karolinska Institutet's Single Cell Atlas
Researchers at Karolinska Institutet have developed a web-based platform that offers an unprecedented view of the human body at the cellular level. The aim is to create an invaluable resource for ...