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Graphene sensor tracks down cancer biomarkers

Graphene sensor tracks down cancer biomarkers

The ideal crystalline structure of graphene is a hexagonal grid. (Photo credit: Wikipedia)
The ideal crystalline structure of graphene is a hexagonal grid. (Photo credit: Wikipedia)
An ultrasensitive biosensor made from the wonder material graphene has been used to detect molecules that indicate an increased risk of developing cancer.

The biosensor has been shown to be more than five times more sensitive than bioassay tests currently in use, and was able to provide results in a matter of minutes, opening up the possibility of a rapid, point-of-care diagnostic tool for patients. The biosensor has been presented today, 19 September, in IOP Publishing’s journal 2D Materials.

To develop a viable biosensor, the researchers, from the University of Swansea, had to create patterned graphene devices using a large substrate area, which was not possible using the traditional exfoliation technique where layers of graphene are stripped from graphite.

Instead, they grew graphene onto a silicon carbide substrate under extremely high temperatures and low pressure to form the basis of the biosensor. The researchers then patterned graphene devices, using semiconductor processing techniques, before attaching a number of bioreceptor molecules to the graphene devices. These receptors were able to bind to, or target, a specific molecule present in blood, saliva or urine.

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