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French Institute of Health and Medical Research (INSERM)

French Institute of Health and Medical Research (INSERM)

A less invasive brain-machine interface using ultrasound

Could a new malaria discovery offer effective treatment for a range of infectious diseases including COVID-19?

What if we could replace damaged blood vessels with brand new ones produced in a laboratory?

What is the effect of fasting on age-related diseases?

There are many indications that fasting promotes longevity. In recent years, much attention has been devoted to so-called caloric restriction mimetics (CMRs), substances that simulate the health-promoting effects of fasting without the need of life-style change. In a study published in EMBO Molecular Medicine, a research team led by Oliver Kepp and Guido Kroemer at

What is the effect of fasting on age-related diseases?

Seeing inside tumors to monitor how effective an anticancer treatment is

A team of physicists at the Institut Lumière Matière (CNRS/Université Claude Bernard Lyon 1), in collaboration with the Cancer Research Center of Lyon (CNRS/INSERM/ Université Claude Bernard Lyon 1/Centre Léon Bérard/Hospices civils de Lyon), has demonstrated the potential, for oncology, of an imaging technique based only on the physical properties of tumors. It can differentiate populations of malignant cells

Seeing inside tumors to monitor how effective an anticancer treatment is

A promising new molecular target for immunotherapy

MUHC scientists part of international team that identifies a key molecule in immune system regulation linked to new genetic disease Following the 2018 Nobel Prize for Medicine, global attention is now more than ever turned toward the promise of immunotherapy in oncology. An international team’s work has shed new light on a molecule called TIM-3

A promising new molecular target for immunotherapy

New hope for regenerative medicine using “cellular dust”

While stem cells have the most therapeutic potential, the benefits of regenerative medicine may best be mobilised using extracellular vesicles (EVs), also known in the past as “cellular dust”. A team of researchers from CNRS, AP-HP, INSERM and Paris Descartes and Paris Diderot Universities have tested these vesicles for the first time in a porcine

New hope for regenerative medicine using “cellular dust”

Stopping epileptic seizures with an electronic device planted in the brain

Researchers have successfully demonstrated how an electronic device implanted directly into the brain can detect, stop and even prevent epileptic seizures. These thin, organic films do minimal damage in the brain, and their electrical properties are well-suited for these types of applications. George Malliaras The researchers, from the University of Cambridge, the École Nationale Supérieure

Stopping epileptic seizures with an electronic device planted in the brain

A humanoid robot to liaise between space station crews

A team of French researchers from the Institut cellule souche et cerveau (Inserm/Université Claude Bernard Lyon 1), led by CNRS senior researcher Peter Ford Dominey, has developed “an autobiographical memory” for the robot Nao, which enables it to pass on knowledge learnt from humans to other, less knowledgable humans. This technological progress could notably be

A humanoid robot to liaise between space station crews

An electronic micropump to deliver treatments deep within the brain

Many potentially efficient drugs have been created to treat neurological disorders, but they cannot be used in practice. Typically, for a condition such as epilepsy, it is essential to act at exactly the right time and place in the brain. For this reason, the team of researchers led by Christophe Bernard at Inserm Unit 1106,

An electronic micropump to deliver treatments deep within the brain

A significant breakthrough could revolutionize surgical practice and regenerative medicine

Innovative strategy to facilitate organ repair A significant breakthrough could revolutionize surgical practice and regenerative medicine. A team led by Ludwik Leibler from the Laboratoire Matière Molle et Chimie (CNRS/ESPCI Paris Tech) and Didier Letourneur from the Laboratoire Recherche Vasculaire Translationnelle (INSERM/Universités Paris Diderot and Paris 13), has just demonstrated that the principle of adhesion

A significant breakthrough could revolutionize surgical practice and regenerative medicine

Exposure to general anaesthesia could increase the risk of dementia in elderly by 35 percent

Exposure to general anaesthesia increases the risk of dementia in the elderly by 35%, says new research presented at Euroanaesthesia, the annual congress of the European Society of Anaesthesiology (ESA). The research is by Dr Francois Sztark, INSERM and University of Bordeaux, France, and colleagues. Postoperative cognitive dysfunction, or POCD, could be associated with dementia

Exposure to general anaesthesia could increase the risk of dementia in elderly by 35 percent

Introduction:

Welcome to the French Institute of Health and Medical Research (Institut national de la santé et de la recherche médicale or Inserm), France’s premier research institute dedicated to medical research and human health. Since its inception in 1964, Inserm has been at the epicenter of breakthroughs in understanding and treating diseases. With a commitment to excellence, innovation, and multidisciplinary collaboration, Inserm stands as a global leader in the biomedical and public health sectors.

History:

Inserm was established to foster cutting-edge research in the fields of health and medicine, addressing both fundamental and translational aspects. Over the decades, it has played a pivotal role in promoting health research, contributing significantly to advancements in medical science. The institute’s focus spans from molecular biology and genetics to public health and therapeutic innovations, embodying a holistic approach to tackling health challenges.

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French Institute of Health and Medical Research
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French Institute of Health and Medical Research Discovery

Top 10 Innovations:

  1. Pioneering Gene Therapy Techniques: Inserm researchers have been instrumental in the development of innovative gene therapy methods to treat genetic disorders.
  2. Advancements in HIV/AIDS Research: Significant contributions to understanding and treating HIV/AIDS, including key insights into the virus’s life cycle and resistance mechanisms.
  3. Breakthroughs in Cancer Therapy: Developing novel therapeutic strategies and targeted treatments for various types of cancer.
  4. Neuroscience and Neurodegenerative Diseases: Groundbreaking research in understanding brain function and tackling diseases like Alzheimer’s and Parkinson’s.
  5. Cardiovascular Disease Research: Pioneering work in understanding the mechanisms of heart diseases and developing new treatment approaches.
  6. Stem Cell Research: Contributing to major advancements in stem cell biology and its therapeutic applications.
  7. Innovations in Public Health: Leading research in epidemiology and public health to inform policy and improve health care systems.
  8. Vaccine Development: Contributions to the development of vaccines, including those for COVID-19.
  9. Understanding Metabolic Diseases: Advancing knowledge in metabolic disorders like diabetes and obesity.
  10. Telemedicine and Digital Health Innovations: Pioneering work in telemedicine, enhancing access to health care and monitoring.

Top 10 Innovators:

See Also

  1. Jean Dausset: Nobel Laureate for his work in immunology, particularly in the discovery of the major histocompatibility complex.
  2. Françoise Barré-Sinoussi: Awarded the Nobel Prize for her co-discovery of the human immunodeficiency virus (HIV).
  3. Luc Montagnier: Sharing the Nobel Prize with Barré-Sinoussi for the discovery of HIV.
  4. Axel Kahn: A renowned geneticist known for his work in molecular genetics and bioethics.
  5. Philippe Sansonetti: His groundbreaking work in microbiology has provided deep insights into infectious diseases.
  6. Alain Fischer: Known for his pioneering work in the field of pediatric immunology and gene therapy.
  7. Jules Hoffmann: Nobel Prize in Physiology or Medicine for discoveries concerning the activation of innate immunity.
  8. Margaret Buckingham: Recognized for her contributions to developmental biology and stem cell research.
  9. Catherine Lubetzki: Notable for her work in neurology, particularly multiple sclerosis.
  10. Gilles Thomas: A prominent figure in the field of genetic epidemiology and the study of genetic diseases.

The French Institute of Health and Medical Research (Inserm) represents a beacon of hope and innovation in the pursuit of understanding human health and disease. Through its relentless dedication to research and discovery, Inserm continues to make monumental contributions to medical science, improving lives and shaping the future of healthcare.

 

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