Cincinnati Children’s Hospital Medical Center

Cincinnati Children’s Hospital Medical Center (CCHMC) is a 700-bed pediatric hospital located in Cincinnati, Ohio

A true universal Ebola vaccine?

Looks like gene therapy can reverse sickle cell anemia

Treatment Uses Reduced-Intensity Preconditioning to Enhance Its Global Transportability After over a decade of preclinical research and development, a new gene therapy treatment for sickle cell anemia (SCA) is reversing disease symptoms in two adults and showing early potential for transportability to resource-challenged parts of the world where SCA is most common. Preliminary data from a pilot Phase

Looks like gene therapy can reverse sickle cell anemia

A pilot study indicates that artificial intelligence may be useful in predicting which students are at higher risk of perpetrating school violence

The researchers found that machine learning – the science of getting computers to learn over time without human intervention – is as accurate as a team of child and adolescent psychiatrists, including a forensic psychiatrist, in determining risk for school violence. “Previous violent behavior, impulsivity, school problems and negative attitudes were correlated with risk to

A pilot study indicates that artificial intelligence may be useful in predicting which students are at higher risk of perpetrating school violence

Human colon organoids change the study of GI disease

Stem Cell Derived Organoids Fill Gap in Modeling Common Ailments Scientists used human pluripotent stem cells to generate human embryonic colons in a laboratory that function much like natural human tissues when transplanted into mice, according to research published June 22 in Cell Stem Cell. The study is believed to be the first time human

Human colon organoids change the study of GI disease

Investigators now can grow parts of the human stomach to study disease and model new treatments

Researchers Can Grow Functional Stomach and Intestinal Tissues to Study Diseases, New Drugs Scientists report in Nature using pluripotent stem cells to generate human stomach tissues in a petri dish that produce acid and digestive enzymes. Publishing their findings online Jan. 4, researchers at Cincinnati Children’s Hospital Medical Center grew tissues from the stomach’s corpus/fundus

Investigators now can grow parts of the human stomach to study disease and model new treatments

Reprogrammed cells grow into new blood vessels

By transforming human scar cells into blood vessel cells, scientists at Houston Methodist may have discovered a new way to repair damaged tissue. The method, described in an upcoming issue of Circulation (early online), appeared to improve blood flow, oxygenation, and nutrition to areas in need. Cardiovascular scientists at Houston Methodist, with colleagues at Stanford

Reprogrammed cells grow into new blood vessels

Scientists generate first human stomach tissue in lab with stem cells

Scientists used pluripotent stem cells to generate functional, three-dimensional human stomach tissue in a laboratory – creating an unprecedented tool for researching the development and diseases of an organ central to several public health crises, ranging from cancer to diabetes. Scientists at Cincinnati Children’s Hospital Medical Center report Oct. 29 in Nature they used human

Scientists generate first human stomach tissue in lab with stem cells

Mouse study shows gene therapy may be possible cure for Hurler syndrome

Researchers cautioned that study results involving laboratory mouse models do not always translate into clinical treatment of human patients Researchers used blood platelets and bone marrow cells to deliver potentially curative to mouse models of the human genetic disorder Hurler syndrome – an often fatal condition that causes organ damage and other medical complications. Scientists

Mouse study shows gene therapy may be possible cure for Hurler syndrome

Developing a new tool to help us anticipate violent behavior

“Developing a new tool to help us anticipate violent behavior is our ultimate goal.” A new study indicates that a simple saliva test could be an effective tool in predicting violent behavior. The pilot study, led by Cincinnati Children’s Hospital Medical Center and published this week online in the journal Psychiatric Quarterly, suggests a link

Developing a new tool to help us anticipate violent behavior

UAMS researchers make breakthrough in radiation protection

Hauer-Jensen said the finding could potentially revolutionize the way radiation exposure is treated. Researchers at the University of Arkansas for Medical Sciences (UAMS) have shown for the first time that boosting a protein pathway in the body’s circulatory system can act as protection against potentially fatal radiation poisoning. The breakthrough was published online June 24

UAMS researchers make breakthrough in radiation protection

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