Initial clinical tests show that biosensors could pave the way for a personalized antibiotherapy in the future
Personalized drug therapy, adjusting the dose, dosage intervals, and the duration of treatment to fit individual patients’ needs, are getting more and more important. Frequently, medications are dosed in such a way that each patient receives the same standardized amount of a certain drug. Thereby, clinical conditions of the patient, such as state of health, metabolism, or other physical factors, are often not sufficiently considered. A researcher team at the University of Freiburg has developed a bioanalytical method which can measure the class of ?-lactam antibiotics in human blood on-site – in the operating room, intensive ward or doctor’s office, as well as on a house call. “This way, we can easily determine just how quickly the human body metabolizes a drug,” said the microsystems engineer Dr. Can Dincer, who is the head of the research team. The researchers recently published their results in the journal “Scientific Reports”.
This new method makes it possible to individually adjust the necessary dose of a medication for each patient. “We’ve proven the applicability of our system for a personalized antibiotherapy by on-site monitoring the clearance of drugs in two patients, who were treated with ß-lactam antibiotics, undergoing surgery” Dincer said. “Based on these results, our next step will be to perform a quantitative cohort study that will determine the usefulness of personalized antibiotherapy.”, he added.
Already at the end of 2016, the research team presented its biosensor technology that allows the rapid and simultaneous monitoring of different antibiotics in human blood (www.pr.uni-freiburg.de/pm/2016/pm.2016-11-14.159). In their recently published study, the scientists further developed their system by implementing another natural sensor protein that can quantify ?-lactam antibiotics. In human medicine, ?-lactam antibiotics are often used to prevent and treat infectious diseases.
Learn more: Personalize your medication dosages
The Latest on: Personalized medicine
[google_news title=”” keyword=”personalized medicine” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]- The Role of Data Science in Revolutionizing Personalized Medicine and Drug Discoveryon May 9, 2024 at 1:49 am
Genomic data holds immense promise in personalized medicine. Advances in DNA sequencing technologies have made it possible to decode an individual's entire genome, uncovering genetic variations that ...
- Enhancing Beauty: How AI Transforms Aesthetic Medicine From Patient Desires To Real Outcomeson May 8, 2024 at 5:31 am
Physicians strive to set realistic expectations to build trust and ensure patient satisfaction, but often, the lack of objective tools impedes their efforts.
- Keck Medicine of USC earns ‘LGBTQ+ Healthcare Equality Leader’ 2024 designationon May 7, 2024 at 5:00 pm
Keck Medicine of USC hospitals and USC Student Health, part of Keck Medicine, received the ‘LGBTQ+ Healthcare Equality Leader’ designation in the Human Rights Campaign Foundation’s 2024 Healthcare ...
- Biocartis and Merck to Collaborate on Improving Patient Access to Personalized Medicine in Middle East and North Africa (MEA) Regionon May 7, 2024 at 8:56 am
Biocartis (Mechelen, Belgium) announced an expansion of its collaboration with Merck Serono Middle East and Merck Saudi Ltd., both affiliates of Merck KGaA (“Merck”). The collaboration aims to improve ...
- Modern Vision Centers: Redefining the Patient Eye Care Experience Through a Fusion of Expertise, Technology, and Personalized Solutionson May 7, 2024 at 5:15 am
This unique collaboration combines clinical excellence with a personalized experience that is seldom found in medicine. MVC partners offer advanced treatments for vision correction such as LASIK and ...
- Personalized screening early in pregnancy may improve preeclampsia detectionon May 6, 2024 at 8:00 am
Study suggests more extensive screening method in the first trimester of pregnancy may improve detection of preeclampsia ...
- Can a personalized antibiotics, prebiotics, and probiotics combo help treat IBS?on May 4, 2024 at 11:00 pm
A pilot study suggests that a personalized combination of antibiotics, prebiotics, and probiotics may help treat the symptoms of post-infectious irritable bowel syndrome (IBS).
- Opinion: I mix Iranian traditional medicine with my Western training to help my patients healon May 3, 2024 at 1:00 pm
Iranian traditional medicine, also known as Persian medicine, is among the world’s oldest holistic healing systems. Its principles have been passed down through centuries, emphasizing the interplay ...
- Advancing genomic medicine: National Cancer Center Japan's role in personalized cancer treatmenton May 2, 2024 at 5:00 pm
In a significant stride towards personalized cancer care, the National Cancer Center Japan (NCCJ) has marked a decade of progress in cancer genomic medicine (CGM).
- Indulge in a world of personalized care and wellness at Strata Integrated Wellness Spaon May 1, 2024 at 3:12 pm
Strata Integrated Wellness Spa combines healthcare and self-care. The team at Garden of the Gods Resort and Club focuses on understanding your body’s needs from the inside out. FOX21’s Krista Witiak ...
via Google News and Bing medicine