Scientists report that they have discovered a way to tweak genes in the body’s immune cells by using electrical fields.
For the first time, scientists have found a way to efficiently and precisely remove genes from white blood cells of the immune system and to insert beneficial replacements, all in far less time than it normally takes to edit genes.
If the technique can be replicated in other labs, experts said, it may open up profound new possibilities for treating an array of diseases, including cancer, infections like H.I.V. and autoimmune conditions like lupus and rheumatoid arthritis.
The new work, published on Wednesday in the journal Nature, “is a major advance,” said Dr. John Wherry, director of the Institute of Immunology at the University of Pennsylvania, who was not involved in the study.
But because the technique is so new, no patients have yet been treated with white blood cells engineered with it.
“The proof will be when this technology is used to develop a new therapeutic product,” cautioned Dr. Marcela Maus, director of cellular immunotherapy at Massachusetts General Hospital.
That test may not be far away. The researchers have already used the method in the laboratory to alter the abnormal immune cells of children with a rare genetic condition. They plan to return the altered cells to the children in an effort to cure them.
Learn more: Swift Gene-Editing Method May Revolutionize Treatments for Cancer and Infectious Diseases
The Latest on: Gene-editing method using electrical fields
[google_news title=”” keyword=”gene-editing method using electrical fields” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Gene-editing method using electrical fields
- Gene Therapy Newson April 25, 2024 at 5:00 pm
Gene-Editing Offers Hope for People With Hereditary ... 2023 — Many hidden genetic variations can be detected with Chameleolyser, a new method. The information is already yielding new patient ...
- GU Medical Center Distinguished Scientist Seminar Series Illuminates Uses of Gene Editing in Cancer Researchon April 23, 2024 at 5:00 pm
I’ve never really heard of a lab technique that can be used in such a wide variety of fields.” Chari also elaborated on his lab’s collaborations with the National Cancer Institute’s Center for Cancer ...
- Generative A.I. Arrives in the Gene Editing World of CRISPRon April 22, 2024 at 1:48 pm
Much as ChatGPT generates poetry, a new A.I. system devises blueprints for microscopic mechanisms that can edit your DNA.
- Exclusive: Gene editing startup Seamless hires ex-Homology leader, doubles seed roundon April 22, 2024 at 12:00 pm
A small German biotech attempting to crack into the gene editing field with an evolved approach to a decades-old research interest has nabbed former Homology Medicines executive Albert Seymour as CEO.
- Gene editing crops to be colourful could aid weeding, say scientistson April 17, 2024 at 9:37 am
“Today it is a robust and competitive weed in European fields, capable of producing ... control,” the researchers write. “Utilising gene editing to enhance their visual recognition by ...
- Gene Therapy Methods Explainedon April 16, 2024 at 6:17 am
Here, we review some of the most prominent methods for doing this. As the series progresses, we will give specific examples of success. Gene therapy is a medical field that shows promise in ...
- Nvelop launches to deliver gene-editing cargoon April 10, 2024 at 5:00 pm
For example, it may be possible to use Joung’s human-derived envelope proteins with the Liu platform. Jeff Walsh, the CEO of the company, says Nvelop can produce its own gene-editing cargo or ...
- A Bold Gene-Editing Solution Began Testing—Then Hit the Strangest Twiston April 9, 2024 at 5:00 am
While gene-editing is the future ... due to its proximity to the clinic and its use of a different LNP that incorporates an ionizable lipid.” Gene-editing is undoubtedly the future of treating ...
- Stanford doctors help develop first FDA-approved gene-editing treatmenton April 8, 2024 at 5:26 pm
The Food and Drug Administration (FDA) approved the gene therapy Casgevy in ... based on prior work developing a method for human genome editing using the CRISPR/Cas9 system.
via Bing News
