This was a promising result for developing potential therapies
One molecule makes nerve cells grow longer. Another one makes them grow branches. These new experimental manipulations have taken researchers a step closer to understanding how nerve cells are repaired at their farthest reaches after injury. The research was recently published in the Journal of Neuroscience.
“If you injure a peripheral nerve, it will spontaneously regenerate, but it goes very slowly. We’re trying to speed that up,” said Dr. Jeffery Twiss, a professor and head of the biology department at Drexel University in the College of Arts and Sciences, who was senior author of the paper.
But, Twiss said, scientists still have a lot to learn about how nerve cells repair themselves. He and his colleagues are especially interested in how nerve cells are repaired in their longest-reaching sections, their axons. Axons can be up to a meter long in adult human nerve cells, extending away from the cell body toward neighboring nerve cells, with which they exchange signals. Restoring length to damaged axons is essential to restoring nerve function, but coordinating these repairs at a great distance from the cell’s nucleus involves a mix of complex processes within each cell. To gain insight into these processes, they have focused research, including the present study, on repair proteins that are created locally near an injury site in a nerve’s axon.
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Nerve regeneration
- Neurobiology of Peripheral Nerve Regenerationon May 7, 2024 at 8:09 pm
He summarises current basic ideas about the molecular mechanisms involved in both nerve degeneration and regeneration and what approaches can be used to address it experimentally. Heavily illustrated ...
- Retinoic acid in the development, regeneration and maintenance of the nervous systemon May 6, 2024 at 4:59 pm
Elevated RA signalling in the adult triggers axon outgrowth and, consequently, nerve regeneration. RA is also involved in the maintenance of the differentiated state of adult neurons, and ...
- Red light therapy for repairing spinal cord injury passes milestoneon May 6, 2024 at 6:43 am
Patients with spinal cord injury (SCI) could benefit from a future treatment to repair nerve connections using red and near-infrared light.
- Nerve Repair and Regeneration Market Estimated To Reach USD 32.4 Billion By 2033on April 28, 2024 at 11:49 pm
According to Market.us, the projected size of the Nerve Repair and Regeneration Market is anticipated to reach around USD 32.4 Billion by the year 2033, indicating a significant surge from its value ...
- Nerve Repair and Regeneration Market Beyond the Horizon Envisioning the Future of Market Size Analysison April 25, 2024 at 9:46 pm
Nerve Repair and Regeneration Market is valued approximately at USD 5.72 billion in 2019 and is anticipated to grow with a healthy growth rate of more than 9.15% over the forecast period 2020-2027.
- New Compound from Blessed Thistle Promotes Functional Nerve Regenerationon April 21, 2024 at 5:00 pm
Regeneration pathways of injured nerves in humans and animals with long axons are accordingly long. This often makes the healing process lengthy and even frequently irreversible because the axons ...
- Thistle extract accelerates nerve regeneration by up to 29%on April 21, 2024 at 5:00 pm
Nature has again proven effective in treating health conditions, this time nerve injury. According to a new study, a compound found in the blessed thistle plant accelerates the regeneration of ...
- New compound from blessed thistle may promote functional nerve regenerationon April 18, 2024 at 5:00 pm
Their article "Cnicin promotes functional nerve regeneration" features clinical studies and is published in Phytomedicine. Blessed thistle (Cnicus benedictus) is a plant in the family Asteraceae ...
- New compound from blessed thistle promotes functional nerve regenerationon April 18, 2024 at 5:00 pm
The study 'Cnicin promotes functional nerve regeneration' was published in Phytomedicine. Rapid help for nerves Regeneration pathways of injured nerves in humans and animals with long axons are ...
- A potential active ingredient for nerve regenerationon March 4, 2024 at 2:58 pm
The chances of recovery depend mainly on the speed at which the severed fibers regenerate as this process is time-limited, so usually only short distances can be overcome. Consequently ...
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- Axogen, Inc to Participate at Leerink Partners Healthcare Crossroads Conferenceon May 14, 2024 at 4:00 am
Axogen, Inc. (NASDAQ: AXGN), a global leader in developing and marketing innovative surgical solutions for peripheral nerve injuries, today announced that Karen Zaderej, chairman, chief executive ...
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- Spinal red-light therapy protects and regenerates damaged nerve cellson May 6, 2024 at 11:15 pm
Directly applying red-light therapy to a damaged spinal cord protects and regenerates nerve cells, leading to a return of motor and sensory function, according to new research. The treatment could ...
- Breakthrough laser treatment that could reverse spinal injuries developed by UK scientistson May 5, 2024 at 5:41 am
A new groundbreaking laser treatment, developed by scientists at Birmingham University, could reverse spinal damage in people left paralysed, with the use of near-infared light ...
- Red light therapy for repairing spinal cord injury passes milestoneon May 4, 2024 at 5:00 pm
Surgery after spinal cord injury is ... Patients with spinal cord injury (SCI) could benefit from a future treatment to repair nerve connections using red and near-infrared light.
- Novel fabrication method creates aligned nanofiber hydrogels for tissue regenerationon May 3, 2024 at 10:12 pm
A team of chemists and bioengineers at Rice University and the University of Houston have achieved a significant milestone in their work to create a biomaterial that can be used to grow biological ...
- Thistle extract accelerates nerve regeneration by up to 29%on April 21, 2024 at 5:00 pm
That’s because the Schwann cells responsible for regeneration stop providing ... a way of assessing the recovery of function after sciatic nerve injury in animal models. Allodynia – pain ...
- Researchers discover a protein that stimulates optic nerve regenerationon March 26, 2024 at 7:43 am
A newly investigated regeneration factor could change that ... and that they might be able to harness it to regrow nerves after injury. They took adult mice with crushed optic nerves and ...
- Nerve Repair and Grafting in the Upper Extremityon March 5, 2022 at 1:52 am
Splinting for specific nerve injuries should prevent contracture during the months required for regeneration. After ulnar nerve repair, blocking the MP joints in 30° of flexion allows active ...
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