Researchers at the University of San Diego School of Medicine describe a new way to treat adult amyotrophic lateral sclerosis in mice. The result is the long-term suppression of the degenerative motor neuron disorder if the treatment is delivered prior to disease onset .
ALS is a neurodegenerative disease that affects nerve cells in the brain and spinal cord. More than 5,000 Americans are diagnosed with ALS each year and there are an estimated 30000 persons currently living with the disease. There is currently no cure and the majority of patients live between two to five years after diagnosis .
Of the two types of ALS, Sporadic is the most common form and accounts for 90 to 95% of all cases. It can affect anyone. Familial ALS accounts for 5 to 10% of all cases in the US and it is inherited.
This therapeutic approach provides the most potent therapy ever demonstrated in mouse models of the mutated gene linked to ALS. It is also likely to be effective in treatment of other hereditary forms of ALSĀ and possibly other spinal neurodegenerative disorders.
Researchers also tested the injection approach in adult pigs using an injection device developed for use in adult humans and found the procedure could be performed reliably and without surgical complications.
Learn more: Injection of Virus-Delivered Gene Silencer Blocks ALS Degeneration, Saves Motor Function
Go deeper with Bing News on:
Amyotrophic lateral sclerosis
- Brain-computer interface translates ALS patient's brain activity into spoken words
Researchers successfully used a brain-computer interface to synthesize speech directly from brain activity in an ALS patient, achieving 80% word recognition accuracy by listeners, showcasing the ...
- Vowel intelligibility testing may help monitor progression for people with ALS
Approximately 31,000 people are living with amyotrophic lateral sclerosis (ALS) in the United States, with an average of 5,000 new cases every year, according to the Centers for Disease Control and ...
- Clene Reports First Quarter 2024 Financial Results and Recent Operating Highlights
including amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS), today announced its first quarter 2024 financial results and provided recent operating highlights for the CNM-Au8 clinical ...
- Gland Pharma bags USFDA nod for amyotrophic lateral sclerosis injection Edaravone
Hyderabad: Gland Pharma Limited, a generic injectable-focused pharmaceutical company, has received approval from the United States Food and Drug Administration (USFDA) for Edaravone Injection, 30 ...
- Former Salisbury men’s lacrosse goalie Johnny Rodriguez vows to ‘fight like hell’ against ALS diagnosis
Gambrills resident and Mount Saint Joseph graduate Johnny Rodriguez has accepted his ALS diagnosis as a challenge.
Go deeper with Google Headlines on:
Amyotrophic lateral sclerosis
[google_news title=”” keyword=”capturing microplastics” num_posts=”5″ blurb_length=”0″ show_thumb=”left”]
Go deeper with Bing News on:
ALS
- Striking out ALS: Wife throws first pitch at Husker game in honor of husband’s memory
So it was only fitting that Ashley threw out the first pitch of Friday night’s Husker game in honor of Scott, who died in August. After graduation, Scott worked in college football for nine years.
- Multimillion-dollar donation impacting ALS research at University of Cincinnati clinic
May is ALS Awareness Month, and UC Health is already making upgrades and hires after receiving a $13.5 million donation just days ago.
- 'You become a prisoner of your own body': Local woman advocates for research after father loses battle to ALS
ALS or Amyotrophic Lateral Sclerosis, better known to many as Lou Gehrig's Disease, is a degenerative nervous system disease that weakens muscles and impacts total body function.
- Why I share with others the details of my late husband’s life with ALS
Columnist Juliet Taylor shares an ALS Awareness Month reflection on love, loss, and hope for a better future in life with ALS.
- PhD student wins 2024 Illinois Innovation Award for work in ALS
A University of Illinois PhD student in bioengineering won a $20,000 Innovation Award for her work on next-generation therapies for ALS.
Go deeper with Google Headlines on:
ALS
[google_news title=”” keyword=”ALS” num_posts=”5″ blurb_length=”0″ show_thumb=”left”]