McMaster researchers have come up a way for inventing molecule probes to quickly identify deadly bacterial strains of infectious disease.
The find, published as a “hot paper” by a German scientific journal because of its importance, shows promise for detecting specific strains of bacteria and tracking their specific trail of illness.
“With this new technology we will be able to develop molecular tools to recognize any superbug down to the specific strain, and there will be many wide-ranging applications,” said Yingfu Li, principal investigator and a professor of biochemistry and biomedical sciences for the Michael G. DeGroote School of Medicine at McMaster.
The scientists have found a way to make DNAzymes, or single-stranded catalytic DNA molecules from a simple test tube technique that allows for isolation of rare DNA sequences with special functions.
The research team’s first success was the development of a molecular probe that precisely recognizes the strain which caused the 2011 Hamilton, Ont. outbreak of Clostridium difficile infection. This strain was very infectious, resistant to antibiotics and even fatal to some patients. Instead of having to do several different tests to narrow down to a positive identification of the specific strain, the researchers can now quickly pinpoint this superbug using their new molecular probe.
“This sets up the stage for numerous other applications where we can exploit synthetic DNAzyme probes for diagnosing infectious disease,” said Li.
The test can be done in less than an hour, compared to the current 48 hours, allowing for rapid, more accurate treatment of patients.
“This technology can be extended to the further discovery of other superbug strain-specific pathogens. For example, such technology would prove useful in the identification of hypervirulent or resistant strains, implementation of the most appropriate strain-specific treatments and tracking of outbreaks”, said Bruno Salena, a co-author of the study, an associate professor of medicine for the Michael G. DeGroote School of Medicine and a gastroenterologist with Hamilton Health Sciences.
“This technology is inexpensive, accessible without a lab, and will ultimately be adaptable to identify not just many other bacteria or viruses, but even other diseases,” he said.
Read more: New infectious disease test promises quick diagnosis
The Latest on: Infectious disease test
[google_news title=”” keyword=”infectious disease test” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Infectious disease test
- Pulmonary Function Teston May 9, 2024 at 7:38 am
A pulmonary function test measures how well your lungs work. Spirometry and a lung diffusion test are two examples.
- Global Skin Allergy Testing Market Expected to Reach $771.5 Million by 2028on May 9, 2024 at 2:27 am
BOSTON, May 9, 2024 /PRNewswire/ -- "According to the latest BCC Research study, the demand for Global Skin Allergy Testing Market is expected to grow from $560 million in 2023 and is projected to ...
- Here’s How Long the CDC Says to Isolate if You Test Positive for COVID in 2024on May 8, 2024 at 1:53 pm
And while the virus continues to pop up (like the latest FLiRT COVID variants), the Centers for Disease Control and Prevention (CDC) has changed its COVID-19 protocol recommendations for 2024, ...
- Google DeepMind’s AlphaFold 3 could speed up drug discovery for diseaseson May 8, 2024 at 10:30 am
Dr Nicole Wheeler, an expert in microbiology at the University of Birmingham, said AlphaFold 3 could significantly speed up the drug discovery pipeline, as “physically producing and testing biological ...
- Farmers to benefit from rapid disease testing system for animalson May 7, 2024 at 4:24 pm
The way existing livestock disease testing works, farmers can wait days or even weeks on outside labs. The Kalix PCR testing system, licensed under University of Dayton, provides on-site testing to ...
- FDA Finalizes Rule to Phase Out Enforcement Discretion of Laboratory-Developed Testson May 7, 2024 at 2:53 pm
and cellular and tissue-based products donor screening tests required for infectious disease testing, or for determination of blood group and Rh factors. Such tests must be licensed, approved, or ...
- Global Veterinary Infectious Disease Diagnostics Market to Witness Exponential Growth, Reaching USD 4.9 Billion by 2033on May 6, 2024 at 8:37 pm
The global veterinary infectious disease diagnostics market is projected to have a high-paced CAGR of 10.1% during the forecast period. The current valuation of the veterinary infectious disease ...
- Infectious disease DNA tester Karius nets $100M to expand liquid biopsy reachon May 3, 2024 at 9:18 am
The infectious disease diagnostic developer Karius has secured another $100 million to help expand the reach of its microbial DNA test designed to detect more than 1,000 different pathogens from a | ...
- The FDA Will Test You Nowon May 2, 2024 at 1:42 pm
The agency makes a power grab to regulate lab tests like medical devices.
- Karius Raises $100M Co-Led by Khosla Ventures, 5AM Ventures and Gilde Healthcare, to Expand Access to Advanced Genomic Diagnostics in Infectious Disease, Addressing ...on May 2, 2024 at 12:00 pm
Karius®, Inc., a world leader in genomic diagnostics for infectious disease, today announced it has secured $100 million in Series C funding. The roun ...
via Bing News