NIH Scientists and Collaborators Report Positive Results in Monkeys
One shot of an experimental vaccine made from two Ebola virus gene segments incorporated into a chimpanzee cold virus vector (called chimp adenovirus type 3 or ChAd3) protected all four macaque monkeys exposed to high levels of Ebola virus 5 weeks after inoculation, report National Institutes of Health (NIH) scientists and their collaborators. The ability of the ChAd3 Ebola virus vaccine to elicit rapid protection in monkeys is notable as the world health community battles an ongoing Ebola virus disease outbreak in West Africa. While the protective effects of the single shot waned over time, two out of four inoculated animals were protected when challenged with Ebola virus 10 months after vaccination.
The research team, headed by Nancy J. Sullivan, Ph.D., of the National Institute of Allergy and Infectious Diseases Vaccine Research Center, also demonstrated increased levels of durable protection using an additional vaccine. They inoculated four macaques first with the ChAd3 Ebola vaccine, then 8 weeks later with a booster vaccine containing Ebola virus gene segments incorporated into a different vector (a poxvirus). Ten months after the initial inoculation, four out of four animals that received both shots were fully protected from infection with high doses of Ebola virus, demonstrating that the prime-boost regimen resulted in durable protection.
The Latest on: Ebola
[google_news title=”” keyword=”Ebola” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: Ebola
- Ebola's exponential growthon May 16, 2024 at 5:00 pm
The U.S. government’s Centers for Disease Control warned recently that we could have 1.4 million cases of Ebola by January. By Gwynne Dyer - Here are two good things about the Ebola virus. It is ...
- Lassa fever case in Paris: What you need to knowon May 13, 2024 at 11:00 am
A case of Lassa fever has been reported in Paris, France, sparking lurid warnings about the "horrific Ebola-like bug".
- Newsday - How I survived Ebola but it changed my life forever - BBC Soundson May 13, 2024 at 10:01 am
Preston Gorman on how he dealt with PTSD after recovering from the virus ...
- Ebola Outbreak in West Africa, 2013-2014on May 12, 2024 at 5:00 pm
The Ebola virus disease outbreak now ravaging parts of West Africa is the largest on record. In fact, West Africa has seen more cases of the disease in 2014 than have been seen in all other ...
- Lassa fever: Ebola-like bug that causes bleeding from the eyes and spread by rats found in Parison May 12, 2024 at 1:05 am
A new case of the Ebola-like Lassa virus, which causes many of the same symptoms including bleeding from the nose and eyes, has been detected in a patient in Paris, France ...
- Newsday - 'We've been handling Ebola as an emergency for a year' - DR Congo minister - BBC Soundson May 8, 2024 at 12:10 am
Democratic Republic of Congo outbreak declared public health emergency by WHO ...
- Chinese scientists create mutant Ebola virus that killed hamsters to 'avoid biosafety rules'on May 7, 2024 at 2:10 pm
Scientists in China created a mutant Ebola virus in a lab that killed hamsters to "avoid biosafety rules". Researchers at Hebei Medical University combined a contagious livestock disease and a protein ...
- Horrific Ebola-like bug that causes bleeding from the eyes detected in Paris after ‘worst outbreak on record’on May 7, 2024 at 8:01 am
A CASE of Lassa fever has been reported in the Paris region. The patient, a soldier who had recently returned from abroad, is now being treated at the Bégin military hospital in Saint-Mandé, ...
- Chinese scientists create new mutant Ebola strain with horror eye symptomson May 7, 2024 at 5:35 am
Researchers at Hebei Medical University in China have used a protein that is found in Ebola alongside a contagious disease in hamsters that wiped out the rodents ...
- Chinese scientists create mutant Ebola virus in labon May 5, 2024 at 5:00 pm
While the experiment may spark fears of another lab leak, the researchers say their goal was to find the right animal models that can safely mimic Ebola symptoms in a lab setting. The study suggested ...
via Bing News