retinitis pigmentosa

By the age of four months, the retinas of mice carrying a mutation in the gene encoding PDE6? (left) are thin and lack rod photoreceptors (red). But mice who have had this mutation corrected through the PESpRY system (right) have much thicker retinas containing numerous rod cells. CREDIT © 2023 Qin et al. Originally published in Journal of Experimental Medicine. https://doi.org/10.1084/jem.20220776

Researchers have successfully restored the vision of mice with retinitis pigmentosa

Researchers have reversed congenital blindness in mice

CRISPR to Reverse Retinitis Pigmentosa and Restore Visual Function in Mouse Model

Retinal prosthesis a step closer to restoring the ability of neurons in the retina to respond to light

CRISPR Used to Repair Blindness-causing Genetic Defect in Patient-derived Stem Cells – Retinitis Pigmentosa

Images of normal (above) and diseased retinas. Patients with MFRP mutations, a cause of retinitis pigmentosa, lose the function of most retinal cells, particularly at the periphery of the retina, leaving them with drastically reduced vision. Personalized gene therapy, using iPS cells, may offer a way to correct this genetic disorder.

Patient-Specific Stem Cells and Personalized Gene Therapy

University Hospitals Eye Institute to offer ‘first bionic eye’ retinal chip for blind

Holographic Technique Could Lead to Bionic Vision

Argus II becomes first “bionic eye” to gain approval for sale in U.S.

Retinal Prosthesis posts encouraging results in clinical trial

“Artificial retina” wins European approval

New Retinal Implant Enables Blind People to See Shapes and Objects