Using CRISPR gene editing, a team from Children’s Hospital of Philadelphia (CHOP) and Penn Medicine have thwarted a lethal lung disease in an animal model in which a harmful mutation causes... Read more
CHOP/Penn Medicine Team Shows first example of base-editing tool to treat a disease in utero in animal models For the first time, scientists have performed prenatal gene editing to prevent a... Read more
Research from the University of Pennsylvania shows that using minimally invasive electrical currents on the prefrontal cortex can reduce the desire to carry out physical and sexual assault a... Read more
Ludwig researchers describe how acidity turns oxygen-starved cancer cells dormant and drug resistant—and a potentially easy way reverse the effect. A Ludwig Cancer Research study has uncover... Read more
Researchers from the University of Pennsylvania have developed a gene therapy that successfully treats a form of macular degeneration in a canine model. The work sets the stage for translati... Read more
CRISPR-like technique offers clues to mimic protective genetic mutations Using a variation of CRISPR gene editing may be a potential strategy for mimicking the protective effects of a geneti... Read more
Turning on repair mechanisms in cells that survive injury in the heart and other tissues In mammals, including humans, the cells that contract the heart muscle and enable it to beat do not r... Read more
Sleep deprivation – typically administered in controlled, inpatient settings – rapidly reduces symptoms of depression in roughly half of depression patients, according the first meta-analysi... Read more
Combined blood markers correctly detect early pancreatic cancer in human cancer cells A newly identified biomarker panel could pave the way to earlier detection and better treatment for panc... Read more
