One in three adults aged 60 and over suffering from a hip fracture dies within one year. Now, a Purdue University-affiliated startup is moving closer to the start of clinical trials for a novel injectable drug that is targeted to heal broken bones faster and strengthen weak bones.
The Purdue University discovered drug, NOV004, from Novosteo Inc. is unique in that it concentrates at the fracture site while reducing exposure to the rest of the body.
Novosteo, the startup developing the drug, was co-founded by father-son team Philip S. Low, the Presidential Scholar for Drug Discovery and the Ralph C. Corley Distinguished Professor of Chemistry, and Stewart A. Low, the company’s CSO and Visiting Scholar in Purdue’s Department of Chemistry. The treatment was developed in the Purdue laboratory of Low in the Purdue Institute of Drug Discovery. Currently there are 288 clinical trials performed or in process using Purdue-developed medical treatments at 4,841 sites across the globe.
Scott Salka, who recently joined the startup as executive chair, will use his 28 years of experience as a biotechnology entrepreneur to help Novosteo move its innovations from the laboratory to clinical trials and ultimately in to the hands of doctors and patients.
“We have been working on some amazing science with people truly dedicated to making a difference in reducing the mortality and improving the quality of life for our aging population,” said Salka. “We have completed preclinical studies with NOV004 and are looking to take it to clinical trials later this year.”
As CEO, Salka has successfully led efforts to advance novel drugs through preclinical and early clinical development, most recently at publicly traded Ampliphi, now Armata NYSE: ARMP. Prior to that he founded and served as CEO for both Ambit Biosciences, acquired by Daiichi Sankyo OTC: DSNKY, and Rakuten Medical.
Novosteo is already looking at the future use of the injectable-targeted drug for other applications, including dental implants, head and facial fractures, and hip and knee replacements. In addition, Novosteo has a pipeline of drugs for treating an array of musculoskeletal maladies. Salka will present some of the technology at Biocom’s Global Life Science Partnering Conference this month in La Jolla, California.
The Latest Updates from Bing News & Google News
Go deeper with Bing News on:
Bone repair
- Discovering the Collagen Power in Bone Broth: A Deep Dive with Vitauthority
When it comes to superfoods that have stood the test of time, bone broth tops the list. This nutrient-rich liquid, savored for its ability to heal the body and soothe the soul, has been a staple in ...
- Dr. Roach: MRI not recommended for patient with shrapnel lodged in skull
Although I do not need an MRI right now, I am being proactive because I am concerned that I may need one in the future due to my medical conditions.
- A Kingwood woman began restoring dinosaur fossils after work. Now she's turning it into a career.
McClain quit her job as a graphic designer to focus on her preparation and restoration business called Big Sky Fossils.
- Bone Grafts and Substitutes Market Size and Scope, Industry snapshot, Leading Companies and Opportunity Analysis by 2032
Report Ocean recently published a research report titled “Bone Grafts and Substitutes Market” 2024 Forecast to 2032 Analysis by Market Trends.” This study delivers accurate economic projections, ...
- Faster recovery: Irradiated plasma might help bones heal early
Irradiated plasma gives nonunion fractures a healing boost, which improves recovery time. Researchers treated a group of rats with a specific type of plasma called non-thermal atmospheric pressure ...
Go deeper with Google Headlines on:
Bone repair
[google_news title=”” keyword=”bone repair” num_posts=”5″ blurb_length=”0″ show_thumb=”left”]
Go deeper with Bing News on:
Bone strengthening
- National Exercise Day: Benefits of getting your move on
It is National Exercise Day, and getting 30 minutes a day of moderate physical activity should be the goal for everyone, according to the Mayo Clinic.
- Child's Arizona Rock Collection Reveals Jawbone of Marine Who Died in 1951 California Training Exercise
A boy's rock collection in Arizona contained a jawbone identified as that of Marine Capt. Everett Leland Yager, who died in 1951.
- Book Review: 'Nothing But the Bones' is a compelling noir novel at a breakneck pace
Nothing But the Bones,” a prequel to Brian Panowich’s critically acclaimed Bull Mountain series of Southern noir novels, finds Nails McKenna on the run after killing a man in a barroom brawl ...
- Bone found in Arizona belonged to Marine who died over 70 years ago in California
A piece of a child's rock collection has been identified as a jaw bone that belonged to a military service member who died in 1951. The Ramapo College Investigative Genetic Genealogy Center recently ...
- Bone found in Arizona identified as Marine who died in California over 70 years ago
U.S. Marine Corps Capt. Everett Leland Yager died in a military training exercise in the skies of Riverside County, Calif., in July 1951.
Go deeper with Google Headlines on:
Bone strengthening
[google_news title=”” keyword=”bone strengthening” num_posts=”5″ blurb_length=”0″ show_thumb=”left”]