Scientists have developed a 3-D printing method capable of producing highly uniform ‘blocks’ of embryonic stem cells.
These cells – capable of generating all cell types in the body – could be used as the ‘Lego bricks’ to build tissue constructs, larger structures of tissues, and potentially even micro-organs.
The results are published today, Wednesday 4th November, in the journal Biofabrication.
“It was really exciting to see that we could grow embryoid body in such a controlled manner”, explains Wei Sun, a lead author on the paper. “The grown embryoid body is uniform and homogenous, and serves as a much better starting point for further tissue growth.”
The researchers, based at Tsinghua University, Beijing, China, and Drexel University, Philadelphia, USA, used extrusion-based 3-D printing to produce a grid-like 3-D structure to grow embryoid body that demonstrated cell viability and rapid self-renewal for 7 days while maintaining high pluripotentcy.
“Two other common methods of printing these cells are either two-dimensional (in a petri dish) or via the ‘suspension’ method (where a ‘stalagmite’ of cells is built up by material being dropped via gravity.)” continues Wei Sun. “However, these don’t show the same cell uniformity and homogenous proliferation.”
“I think that we’ve produced a 3-D microenvironment which is much more like that found in vivo for growing embryoid body, which explains the higher levels of cell proliferation.”
The researchers hope that this technique can be developed to produce embryoid body at a high throughput, providing the basic building blocks for other researchers to perform experiments on tissue regeneration and/or for drug screening studies.
Read more:Â 3-D printed ‘building blocks’ of life
The Latest on: 3-D printed building blocks of life
[google_news title=”” keyword=”3-D printed building blocks of life” num_posts=”10″ blurb_length=”0″ show_thumb=”left”]
via Google News
The Latest on: 3-D printed building blocks of life
- The 25 Most Defining Pieces of Furniture From the Last 100 Yearson March 28, 2024 at 7:38 am
Three designers, a museum curator, an artist and a design-savvy actress convened at The New York Times to make a list of the most enduring and significant objects for living.
- A day in the life of… a 3D Print Technical Specialiston March 27, 2024 at 8:06 am
Tri-Tech 3D, a UK provider of Stratasys, One Click Metal and XJet 3D printing solutions, is attending TCT 3Sixty 2023. On June 7 and 8 at the NEC in Birmingham, the Tri-Tech 3D stand will be open for ...
- Graphite Likely Enabled Creation Of Earth’s First Prebiotic Moleculeson March 21, 2024 at 2:30 pm
The creation of enough graphite to push along the needed chemical complexity to vector towards life was arguably due to a series of giant impactors that hit Earth beginning some 4.3 billion years ago.
- 3 Body Problem Review: Hard Sci-Fi That Could Have Gone Even Harderon March 21, 2024 at 4:00 am
Netflix's adaptation of the modern sci-fi classic The Three-Body Problem takes awhile to reach terminal velocity.
- Researchers develop 3D-printed wood from its own natural componentson March 19, 2024 at 5:00 pm
the fundamental building blocks of wood. The ink can be used to produce architecturally intricate wood structures via a 3D printing technique known as direct ink writing. The work was recently ...
- These 6 3D printed homes could be built for less than $100,000 each — take a lookon March 19, 2024 at 4:17 pm
Icon and construction giant Lennar are building a 100-printed home neighborhood just north ... Take a look at the winning concepts. But not every 3D printed home has to come with a substantial ...
- Researchers 3D print wood objects from sawdust ink – texture, appearance, and smell similar to the real thingon March 19, 2024 at 8:02 am
Also, in contrast with some other 'wood' 3D printing filaments available today, the new material is simply a water-based ink made of lignin and cellulose, the primary building blocks of natural ...
- These 6 3D printed homes could be built for less than $100,000 each — take a lookon March 17, 2024 at 2:12 am
Icon launched a competition for affordable 3D printed home designs. The winners are now in its digital catalog for developers and buyers.
- Construction Is Underway on the World’s Tallest 3D-Printed Buildingon March 8, 2024 at 1:53 pm
When discussing 3D printing and architecture, the discourse usually focuses on the technology’s ability to help architects see their creations come to life in ... of a given building is on ...
- See Europe’s biggest 3D-printed building being constructed in this fascinating time-lapseon March 7, 2024 at 1:58 pm
It will be intriguing to see what other kinds of 3D-printed buildings come to life in the coming months, especially after seeing them create such a large building in just 140 hours. Doctors have ...
via Bing News