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Home CRISPR-Cas9

HIV-1 Infection Eliminated in Live Animals via Gene Editing

HIV-1 Infection Eliminated in Live Animals via Gene Editing

A permanent cure for HIV infection remains elusive due to the virus’s ability to hide away in latent reservoirs. But now, in new research published in print May 3 in the journal Molecu... Read more

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CRISPR to Reverse Retinitis Pigmentosa and Restore Visual Function in Mouse Model

CRISPR to Reverse Retinitis Pigmentosa and Restore Visual Function in Mouse Model

In mouse models, advanced gene editing tool reprogrammed photoreceptor rods to mutation-resistant cones Using the gene-editing tool CRISPR/Cas9, researchers at University of California San D... Read more

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CRISPR-Cas9 can be delivered directly into the eye of living animals to treat age-related macular degeneration efficiently and safely

CRISPR-Cas9 can be delivered directly into the eye of living animals to treat age-related macular degeneration efficiently and safely

IBS study proves that CRISPR-Cas9 can be delivered directly into the eye of living animals to treat age-related macular degeneration efficiently and safely. It is estimated that almost one i... Read more

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An anti-CRISPR could prevent off-target effects

An anti-CRISPR could prevent off-target effects

Researchers have discovered a way to program cells to inhibit CRISPR-Cas9 activity. “Anti-CRISPR” proteins had previously been isolated from viruses that infect bacteria, but now... Read more

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Genome engineering paves way for sickle cell cure

Genome engineering paves way for sickle cell cure

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease... Read more

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Umeå researcher served a world first (?) CRISPR meal

Umeå researcher served a world first (?) CRISPR meal

For (probably) the first time ever, plants modified with the “genetic scissors” CRISPR-Cas9 has been cultivated, harvested and cooked. Stefan Jansson, professor in Plant Cell and Molecular B... Read more

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Chinese Scientists to Pioneer First Human CRISPR Trial

Chinese Scientists to Pioneer First Human CRISPR Trial

Gene-editing technique to treat lung cancer is due to be tested in people in August Chinese scientists are on the verge of being first in the world to inject people with cells modified using... Read more

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Gene-Drive Modified Organisms Are Not Ready to Be Released Into Environment; New Report Calls for More Research and Robust Assessment

Gene-Drive Modified Organisms Are Not Ready to Be Released Into Environment; New Report Calls for More Research and Robust Assessment

The emerging science of gene drives has the potential to address environmental and public health challenges, but gene-drive modified organisms are not ready to be released into the environme... Read more

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‘Gene drive’ breakthrough creates weaponized mosquito extinction strain

‘Gene drive’ breakthrough creates weaponized mosquito extinction strain

Here’s a question that occurs only to madmen and geneticists: How do you get a gene that kills an organism to spread through a whole population of that organism? You can either make your gen... Read more

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For First Time, Scientists Use CRISPR-Cas9 to Target RNA in Live Cells

For First Time, Scientists Use CRISPR-Cas9 to Target RNA in Live Cells

Technique may open doors to new treatments for many conditions, from cancer to autism The genetic code stored in DNA determines everything from the color of our eyes to our susceptibility to... Read more

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Can CRISPR help edit out female mosquitos?

Can CRISPR help edit out female mosquitos?

The recent discovery of the first male-determining factor in mosquitoes, combined with the gene-editing capabilities of the CRISPR-Cas9 system, could be used to bias mosquito populations fro... Read more

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Curing disease by repairing faulty genes with CRISPR

Curing disease by repairing faulty genes with CRISPR

New delivery method boosts efficiency of CRISPR genome-editing system The genome-editing technique known as CRISPR allows scientists to clip a specific DNA sequence and replace it with a new... Read more

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Sensing the future of living detectors and bioproduction

Sensing the future of living detectors and bioproduction

Plant, yeast, even mammalian cells could be engineered into living detectors of virtually any molecule of interest to improve environmental monitoring, metabolic production of pharmaceutical... Read more

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High-fidelity CRISPR-Cas9 nucleases have no detectable off-target mutations

High-fidelity CRISPR-Cas9 nucleases have no detectable off-target mutations

Mass. General team develops improved version of important gene-editing tool A new engineered version of the gene-editing CRISPR-Cas9 nuclease appears to robustly abolish the unwanted, off-ta... Read more

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Gene-editing technique successfully stops progression of Duchenne muscular dystrophy

Gene-editing technique successfully stops progression of Duchenne muscular dystrophy

If efficiently and safely scaled up in DMD patients, this technique could lead to one of the first successful genome editing-based treatments for this fatal disease, researchers said. DMD, t... Read more

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