Scientists have rolled back time for live mice through systemic cellular reprogramming, according to a study published December 15 in Cell. In mice carrying a mutation leading to premature a... Read more
Synopsis: Uncovering a ‘smoking gun’ in age-related disease Aging is a key risk factor for a variety of devastating, chronic diseases, yet the biological factors that influence when and how... Read more
A new study from UC Berkeley found that tissue health and repair dramatically decline in young mice when half of their blood is replaced with blood from old mice. “Our study suggests that yo... Read more
A team of University of Pittsburgh researchers has uncovered new details about the biology of telomeres, “caps” of DNA that protect the tips of chromosomes and play key roles in a number of... Read more
Safety of NMN being tested in small clinical trial in Japan Much of human health hinges on how well the body manufactures and uses energy. For reasons that remain unclear, cells’ ability to... Read more
A new study in the Proceedings of the National Academy of Sciences provides substantial new evidence that health becomes endangered when aging cells lose control of rogue elements of DNA cal... Read more
Ever since last summer, when Lynn Gemmell’s dog, Bela, was inducted into the trial of a drug that has been shown to significantly lengthen the lives of laboratory mice, she has been the obje... Read more
Due to a loss of functionality in hematopoietic stem cells, immune defects occur during aging. Now, researchers from Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena, Germa... Read more
Chronic inflamation, closely associated with frailty and age-related diseases, is a hallmark of aging. Mayo Clinic researchers have discovered that inhibiting key enzyme pathways reduces inf... Read more
UCLA-led research on telomerase could lead to new strategies for treating disease An enzyme called telomerase plays a significant role in aging and most cancers, but until recently many aspe... Read more
Researchers may have found a way to slow down or prevent memory problems that arise in old age and which can become devastating in patients with dementia. The fresh hope comes from a series... Read more
If proven, it could result in glycine supplements giving our older population a new lease of life. Can the process of aging be delayed or even reversed? Research led by specially appointed P... Read more
Inhibitor tamps down TGF-beta1 and rejuvenates aging stem cells in brain and muscles Whether you’re brainy, brawny or both, you may someday benefit from a drug found to rejuvenate agin... Read more