Scientists at the U.S. Department of Agriculture’s (USDA) Agricultural Research Service (ARS) recently announced that plants could be used to produce nanobodies that quickly block emerging pathogens in human medicine and agriculture.
These nanobodies represent a promising new way to treat viral diseases, including SARS-CoV-2.
Nanobodies are small antibody proteins naturally produced in specific animals like camels, alpacas, and llamas.
ARS researchers turned to evaluating nanobodies to prevent and treat citrus greening disease in citrus trees. These scientists are now using their newly developed and patented SymbiontTM technology to show that nanobodies can be easily produced in a plant system with broad agricultural and public health applications. As a proof-of-concept, researches showed that nanobodies targeting the SARS-CoV-2 virus could be made in plant cells and remain functional in blocking the binding of the SARS-CoV-2 spike protein to its receptor protein: the process responsible for initiating viral infection in human cells.
“We initially wanted to develop sustainable solutions to pathogens in crop production,” said ARS researcher Robert Shatters, Jr. “The results of that research are indeed successful and beneficial for the nation’s agricultural system. But now we are aware of an even greater result — the benefits of producing therapeutics in plants now justify the consideration of using plants to mass produce COVID-19 protein-based therapies.”
AgroSource, Inc. collaborated with USDA-ARS to develop the plant-based production system. They are currently taking the necessary steps to see how they can move this advancement into the commercial sector.
“This is a huge breakthrough for science and innovative solutions to agricultural and public health challenges,” said ARS researcher Michelle Heck. “This cost-efficient, plant-based system proves that there are alternative ways to confront and prevent the spread of emerging pathogens. The approach has the potential to massively expand livelihood development opportunities in rural agricultural areas of the nation and in other countries.”
This research collaboration is in response to the White House’s Executive Order on advancing biotechnology and biomanufacturing innovation for a sustainable, safe, and secure American bioeconomy.
More from: Agricultural Research Service
The Latest Updates from Bing News
Go deeper with Bing News on:
Plant produced nanobodies
- EXCLUSIVE: Biomaterials Company Biofluff Raises $2.5 Million in Seed Round
The company will use the funds to scale production of its plant-based fur with Italy-based manufacturers and enter the luxury market by launching the Savian textile brand.
- What are the stages of a plant's life cycle?
Plants are able to reproduce in two different ways - sexual reproduction and asexual reproducion. Sexual reproduction involves pollen from one flower fertilising the egg of another to produce a seed.
- Plants transformed into detectors of dangerous chemicals
During a drought, soil dries and plants produce ABA. Additional proteins, called receptors, help the plant recognize and respond to ABA. This in turn tells the plant to close pores in its leaves ...
- Churchill Falls, 'here for many years to come,' has room to grow. Here's why
A tunnel leads to the machine room at the Churchill Falls plant, 300 metres under the surface, where 5428 megawatts of electricity is produced. (Patrick Butler/Radio-Canada) "The plant is ...
- Yeast cells can produce drugs for treatment of psychotic disorders
Yeast cells can produce drugs for treatment of psychotic disorders Date: November 10, 2023 Source: Technical University of Denmark Summary: An international team of researchers has demonstrated ...
Go deeper with Bing News on:
Plant-based nanobody production system
- Plant-Based Diets
A plant-based diet is a powerful way to achieve good health. Those who eat a plant-based diet lower their risk for heart disease, type 2 diabetes, obesity, and other health conditions. Research also ...
- Plant-based diet can fight climate change - UN
Switching to a plant-based diet can help ... The environmental impact of meat production is important to many vegetarians and vegans. A UK-based group called #NoBeef lobbies caterers to take ...
- 3 Plant-Based Food Stocks to Bet on in 2024
Plant-based food stocks are coming back into fashion. A few years ago, the hype around the emerging sector was much higher. Beyond Meat (NASDAQ:BYND) was at the Vanguard of the push toward plant-based ...
- Microbial Ecosystems of Plant-based Agricultural Production Systems: Methods, Impacts, and Implications for Crop Improvement and Yield Enhancement
These interactions are sufficiently interdependent that the plant ... production. Research can include all aspects of microbe-microbe and microbe-host interactions that have applications in the health ...
Italy’s decision to ban the production and marketing of cultivated meat products threatens innovations, hinders the fight against climate change and reduces customer choice, according to the ...