The evaporation of sweat on paper pads could be used for fluid transport in wearables over long periods of time. The resulting dry layer of caked salts would preserve a “time-stamped” record of biomarkers of interest.
Orlin D. Velev and co-authors, NC State University
Microfluidic device demonstrates principles of extraction and managing of sweat for up to 10 days, pointing a way forward for more affordable medical testing
Human sweat contains several biomolecules the research community is exploring for noninvasive medical testing. Analyzing sweat for research, however, is often expensive, and devices typically are reliable for only a limited amount of time.
Researchers at North Carolina State University have constructed a paper-based device as a model of wearables that can collect, transport and analyze sweat in next-generation wearable technology. Using a process known as capillary action, akin to water transport in plants, the device uses evaporation to wick fluid that mimics the features of human sweat to a sensor for up to 10 days or longer. They discuss their work in the journal Biomicrofluidics, from AIP Publishing.
The work was a collaboration between Orlin Velev and Michael Dickey, advising the research of graduate students Timothy Shay and Tamoghna Saha, as part of the NSF Center for Advanced Self-Powered Systems of Integrated Sensors and Technologies. The goal is to use the properties of paper to point a way forward for more affordable, longer-term devices.
One central problem for any device in analyzing sweat is that sweat contains salt, which, upon evaporation, will become deposited on a device and interfere with fluid flow. The team’s device densely packs deposited salt crystals, allowing for longer use and a way to study the timing of when chemicals present in the sweat.
“We expected that the flow of the model sweat will be suppressed by the deposition of a salt layer inside the drying pad,” Velev said. “By following the flow of model sweat, we found, quite surprisingly, that such a simple paper construct can achieve continuous sweat pumping and disposal for very long periods.”
Paper microfluidic devices could also be used as wearable patches to assess the course of certain diseases or how well patients adhere to drug regimens.
“The biological markers or drug metabolites that seep in the patient’s sweat over a long period will be captured on the paper pad and preserved in a time-stamped manner to be analyzed later, similar to tree rings preserving the record of tree development,” Dickey said.
Driven by the liquid wicking through paper, the device doesn’t require external power. Its low cost also poses uses for inexpensive medical testing in under-resourced patient populations who struggle to have access to such testing. Such skin patch assays could remove the need to take blood samples.
The team has started a series of human trials to explore how the technology provides longer term biomarker analysis, and they look to resume the trials when pandemic safety measures make it feasible to proceed.
The Latest Updates from Bing News & Google News
Go deeper with Bing News on:
Affordable medical testing
- Study shows the QuickNavi-COVID19 Ag test has a high diagnostic performance for SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in nasopharyngeal samples
Researchers evaluated the diagnostic performance of a COVID-19 antigen test during the recent surge caused by the SARS-CoV-2 Omicron variant.
- The Medical Device Contract Manufacturing market is expected to grow at a CAGR of 10.82% during the forecast period from 2022 to 2027
The Global Medical Device Contract Manufacturing Market is projected to grow at a 10.82% CAGR during the forecast period (2022-2027). The medical device contract manufacturing market is witnessing an ...
- Mumbai: Sugar test in just Rs 10? 'one rupy clinic' going to start at its all centres at railway stations from June 1
Sugar test in just Rs 10, Keep in mind the daily commuters and office governs convenience 'one rupy clinic' going to start at it all centres from June 1. Currently, these centres are available at 25 ...
- Student startup ‘Limber’ makes 3D-printed prostheses affordable and accessible
Student startup Limber is working to provide prosthetics to some of the millions of amputees worldwide lacking access.
- AFC Urgent Care Broadway Offers Affordable Urgent Care and Non-Emergency Medical Services in Englewood, CO
The clinic also offers onsite lab tests for different medical ... being attended to by highly trained and qualified medical professionals and affordable healthcare services. The services are ...
Go deeper with Google Headlines on:
Affordable medical testing
Go deeper with Bing News on:
- ANALYSIS-Millions at risk as India's severe heatwave exposes cooling gaps
As the scorching sun beat down on his fruit cart, Mohammad Ikrar dreaded another day of tossing out dozens of rotting mangoes and melons - a regular practice now as India grapples with an ...
- Climate change has made India’s relentless heat 100 times more likely
In northwest India and Pakistan, a UK analysis finds heat that used to occur every 300 years may now happen about every three years.
- An ode to the blood, sweat and likeability of the IPL
If you're privileged enough not to have to take the IPL seriously, don't. That makes it fun because for many involved with the tournament, the tournament is not fun ...
- COVID-19 once again rising in Charleston, across the state
New cases of COVID-19 have risen nearly threefold over the past month in South Carolina, according to an analysis of public health data.
- Dogs can detect SARS-CoV-2 from an individual's sweat
In a recent study published in the Open Forum Infectious Diseases (OFID) Journal, researchers reported that severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) could be detected by canine ...