Fungi on different surfaces
Scientists from the University of Nottingham have developed a new way to control harmful fungi, without the need to use chemical bioactives like fungicides or antifungals.
Fungi cause diverse, serious societal and economic problems in the UK and globally. As well as causing fatal diseases in humans, fungi devastate food crops and spoil valuable products and materials. This has led to an antifungals/fungicide industry worth around $30bn globally.
There are tight regulations around the use of fungicides and antifungals and there is also growing resistance of fungi to these agents.
In a paper published today in Science Advances, experts from the University’s Schools of Life Sciences, Pharmacy, and Engineering, show how they have developed an innovative solution to tackle fungi, by passively blocking fungal attachment to surfaces using a coating of (meth)acrylate polymers, and so negating the need to use potentially harmful anti-fungals or other bioactive chemicals.
Through previous work, the team found different combinations of fungicides which worked against fungi and also produced new understanding of preservative action against spoilage fungi.
Although these advances meant less use of certain fungicides and chemicals, frequent tightening of regulations around usage are restricting the take up of technologies that still rely on bioactive agents, while spread of resistance worsens the problem. Consequently, potential bioactive-free technologies for combatting fungi are highly attractive to the industry.
In this latest study, scientists show an alternative fungal control strategy, which doesn’t have the ‘killing affect’ of fungicides.
The team identified polymers that resist the attachment of different kinds of fungi, including pathogens. They screened hundreds of (meth)acrylate polymers in high throughput, identifying several that reduce attachment of the human pathogen Candida albicans, the crop pathogen Botrytis cinerea, and other fungi.
Professor Simon Avery, from the School of Life Sciences at the University is a lead investigator on the paper, he said: “This is the first high-throughput study of polymer chemistries resisting fungal attachment.
“Our engagement to date with industry has highlighted a clear need for a new approach to control fungi and the major socioeconomic problems that they cause, as the value of existing strategies using bioactives (antifungals, fungicides) is eroded by growing resistance and regulations.
“This passive, anti-attachment technology that we have been developing addresses this need.”
We have been able to show that different polymers are effective in resisting diverse fungi that have broad socio-economic impacts.”
The Latest Updates from Bing News & Google News
Go deeper with Bing News on:
- Humans are not prepared for a pandemic caused by fungal infections
Changes in the environment and climate, as well as fungicide overuse in agriculture, have driven a rise in fungi capable of infecting people and evading the few drugs designed to fight them.
- A man's voice grew hoarse for no obvious reason. It turns out, he had fungus in his throat.
Over the course of a year, a man's voice grew progressively more hoarse and his speech became shrill and grating, but he didn't know why. Upon examining the man, doctors discovered the reason: Fungus ...
- Kerassentials Reviews- What Should You Know About This Herbal Fungal Eliminator?
Despite being a new product, Kerassentials has become one of the top-selling nail products. The reason is that it brings real benefits to the user, and these benefits get visible within a few weeks.
- Overcoming Onychomycosis Review (Blue Heron Nail Fungus Program)
Toe Fungus Review is a detailed guide prepared by Scott Davis of Blue Heron Health News, which looks into how Jennifer Holmes overcame never-ending nail fungus. Nail fungus is a serious condition ...
- Researchers identify how deadly fungus develops drug resistance - study
However, researchers found the method by which C. neoformans develops resistance to antifungal drugs in a new peer-reviewed study published in the scientific journal Nature Microbiology on Tuesday.
Go deeper with Google Headlines on:
Go deeper with Bing News on:
Anti-attachment fungi technology
- Nanotechnology in Therapeutics
Various nanoforms have been attempted as drug delivery systems, varying from biological substances, such as albumin, gelatin and phospholipids for liposomes, to chemical substances, such as ...
- UM6P Ventures Invests in Akorn Technology to Reduce Global Food Waste
CASABLANCA, Morocco, July 26, 2022 (GLOBE NEWSWIRE) -- Today, UM6P Ventures announces its investment in Akorn Technology ... and inhibiting bacterial and fungal growth. At the same time, it ...
- 15 Best Wrinkle Removers: Your Easy Buying Guide
But new technology is getting better, (just like we are) and now there are more ways to fight those fine lines and deep creases than ever before. We’ve found an emerging group of the best ...
- Miami Media Highlights Feb. 28 to March 6
This article reports on anti-war protests taking place in Russia condemning Vladimir ... Glenn Platt, Armstrong Professor of Network Technology and Management in Emerging Technology in Business + ...
- Microbiology in Aquatic Research
Factors such as the roughness and hydrophobicity of the attachment surface and the pH ... including algae, fungi, and protozoa, and largely exist on the floor and walls of aquatic environments ...