Perelman School of Medicine at the University of Pennsylvania

The Perelman School of Medicine, commonly known as Penn Med, is the medical school of the University of Pennsylvania

A new 20-subtype mRNA flu vaccine could protect against future flu pandemics

Could SARS-CoV-2 transmission be reduced by chewing gum?

A new electronic nose spotted cancer with up to 95 percent accuracy

Reversing blindness with a single injection of a mutation-specific RNA therapy in a patient with a rare genetic disorder

Researchers appear to have halted the osteoporosis process that breaks down bone – in mice

Using magnets to arrange cells to grow new tissues like cartilage

Is giving an entire course of radiation therapy in less than 1 second possible?

Imagine using gene therapy to correct lethal lung diseases before death

Using CRISPR gene editing, a team from Children’s Hospital of Philadelphia (CHOP) and Penn Medicine have thwarted a lethal lung disease in an animal model in which a harmful mutation causes death within hours after birth. This proof-of-concept study, published today in Science Translational Medicine, showed that in uteroediting could be a promising new approach for treating lung diseases

Imagine using gene therapy to correct lethal lung diseases before death

Proof-of-concept in treating congenital disease before birth using CRISPR pre-natal gene editing

CHOP/Penn Medicine Team Shows first example of base-editing tool to treat a disease in utero in animal models For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth. Published today in Nature Medicine, research from Children’s Hospital of Philadelphia (CHOP) and the Perelman

Proof-of-concept in treating congenital disease before birth using CRISPR pre-natal gene editing

Could the intent to commit assault be diminished by electrical brain stimulation?

Research from the University of Pennsylvania shows that using minimally invasive electrical currents on the prefrontal cortex can reduce the desire to carry out physical and sexual assault and increase the perception that such violence is morally wrong Stimulating the prefrontal cortex, the part of the brain responsible for controlling complex ideas and behaviors, can

Could the intent to commit assault be diminished by electrical brain stimulation?

Could simple baking soda boost cancer therapy?

Ludwig researchers describe how acidity turns oxygen-starved cancer cells dormant and drug resistant—and a potentially easy way reverse the effect. A Ludwig Cancer Research study has uncovered an entirely novel mechanism by which cells enter a state of dormancy as tissues starved of oxygen become increasingly acidic. The study, led by Chi Van Dang, scientific

Could simple baking soda boost cancer therapy?

Gene therapy for macular degeneration?

Researchers from the University of Pennsylvania have developed a gene therapy that successfully treats a form of macular degeneration in a canine model. The work sets the stage for translating the findings into a human therapy for an inherited disease that results in a progressive loss of central vision and which is currently untreatable. The study, published

Gene therapy for macular degeneration?

Reducing triglycerides and cholesterol by up to 50 percent with gene editing

CRISPR-like technique offers clues to mimic protective genetic mutations Using a variation of CRISPR gene editing may be a potential strategy for mimicking the protective effects of a genetic mutation linked to lower cholesterol levels and heart disease risks, according to new mouse research from the Perelman School of Medicine at the University of Pennsylvania published this week

Reducing triglycerides and cholesterol by up to 50 percent with gene editing

Injectable gel helps heart muscle regenerate after a heart attack

Turning on repair mechanisms in cells that survive injury in the heart and other tissues In mammals, including humans, the cells that contract the heart muscle and enable it to beat do not regenerate after injury. After a heart attack, there is a dramatic loss of these heart muscle cells and those that survive cannot

Injectable gel helps heart muscle regenerate after a heart attack

Sleep deprivation can reduce depression in almost 50 percent of depression patients

Sleep deprivation – typically administered in controlled, inpatient settings – rapidly reduces symptoms of depression in roughly half of depression patients, according the first meta-analysis on the subject in nearly 30 years, from researchers at the Perelman School of Medicine at the University of Pennsylvania. Partial sleep deprivation (sleep for three to four hours followed by

Sleep deprivation can reduce depression in almost 50 percent of depression patients

Early Detection of Pancreatic Cancer

Combined blood markers correctly detect early pancreatic cancer in human cancer cells A newly identified biomarker panel could pave the way to earlier detection and better treatment for pancreatic cancer, according to new research from the Perelman School of Medicine at University of Pennsylvania. Currently over 53,000 people in the United States are diagnosed with pancreatic cancer — the

Early Detection of Pancreatic Cancer

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Are Cellular Therapies the Future of Autoimmune Disease?
Promising results from small case studies and early clinical trials hint at the potential of CAR-T cell therapy to treat -- and possibly cure -- autoimmune diseases like lupus.
Mira Irons, CEO of College of Physicians of Philadelphia, resigns amid Mütter Museum's ethical review
The College of Physicians of Philadelphia, at 19 S. 22nd St., owns and operates the Mütter Museum. CPP president and CEO Mira Irons resigned Wednesday to take a new job as the museum conducts an ...
The Mystery Around Covid Fatigue
Doctors have seen a spectrum of fatigue associated with Covid: Some people are wiped out after they exert themselves, whereas others experience more constant exhaustion, said Dr. Paul Auwaerter, a ...
Penn Medicine Research Reveals Brain-Blood Barrier’s Surprising Influence on Ant Behavior
The blood-brain barrier (BBB) has been found to play a significant role in controlling behavior critical to how ant colonies function, according to new research from the Perelman School of Medicine at ...
Penn Medicine Triumph: Dr. Carl June to be Honored with 2024 Breakthrough Prize in Life Sciences
CAR T cell therapy pioneer Carl June, MD, the Richard W. Vague Professor in Immunotherapy in the Perelman School of Medicine at the University of Pennsylvania and director of the Center for Cellular I ...

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Mira Irons steps down as head of the College of Physicians, Mütter Museum
Since 2021, she oversaw the College, the Mütter Museum, and the Historical Medical Library. Changes to the Mütter Museum during her tenure made her a decisive figure.
The Future of Medicine Emerges in University City:…
Wexford Science & Technology, LLC and the University of Pennsylvania today announced that the University has signed a lease for new laboratory space that will usher in a wave of novel vaccine, ...
University of Pennsylvania
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Affirmative Action, Population Health, and the Importance of Opportunity and Hope
Perelman School of Medicine, the Leonard Davis Institute of Health Economics, and the Opportunity for Health Lab, University of Pennsylvania, Philadelphia.
Bye, DEI. Don't let the door hit you on the way out
Discovery have said recently that high-profile ... a retired dean for curriculum and co-director of the renal division at the University of Pennsylvania's Perelman School of Medicine, wrote an ...

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Perelman School of Medicine at the University of Pennsylvania

The Perelman School of Medicine, commonly known as Penn Med, is the medical school of the University of Pennsylvania

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