University of Texas Southwestern Medical Center

The University of Texas Southwestern Medical Center (UT Southwestern) is one of the leading medical education and biomedical research institutions in the United States.

Fighting cancer by reviving exhausted immune cells could help T cells effectively attack solid tumors

Artificial intelligence can predict depression patient outcomes based on EEG

Predicting depression outcomes using artificial intelligence

Studies show brain activity patterns influence effect of antidepressants The psychiatry field has long sought answers to explain why antidepressants help only some people. Is a patient’s recovery due merely to a placebo effect – the self-fulfilling belief that a treatment will work – or can the biology of the person influence the outcome? Two

Predicting depression outcomes using artificial intelligence

Machine learning can help predict the risk of heart failure in diabetes patients

Investigators used artificial intelligence to identify top 10 variables that can predict, with a high degree of accuracy, future heart failure among patients living with diabetes Heart failure is an important potential complication of type 2 diabetes that occurs frequently and can lead to death or disability. Earlier this month, late-breaking trial results revealed that

Machine learning can help predict the risk of heart failure in diabetes patients

A promising path to a vaccine or drug for late-onset Alzheimer’s

UTSW researchers neutralize genetic risk factor found in 50 to 80 percent of human cases UT Southwestern researchers have succeeded in neutralizing what they believe is a primary factor in late-onset Alzheimer’s disease, opening the door to development of a drug that could be administered before age 40, and taken for life, to potentially prevent the

A promising path to a vaccine or drug for late-onset Alzheimer’s

You might eventually be able to eat as much as you want without gaining weight with a new gene discovery

It sounds too good to be true, but a novel approach that might allow you to eat as much as you want without gaining weight could be a reality in the near future. When a single gene known as RCAN1 was removed in mice and they were fed, they failed to gain weight, even after

You might eventually be able to eat as much as you want without gaining weight with a new gene discovery

New ability to forecast dementia from single molecule

Team joins national network focused on neurodegenerative disorders Scientists who recently identified the molecular start of Alzheimer’s disease have used that finding to determine that it should be possible to forecast which type of dementia will develop over time – a form of personalized medicine for neurodegenerative diseases. A new study from UT Southwestern shows that

New ability to forecast dementia from single molecule

A DNA vaccine for Alzheimer’s moves closer to human trial

A DNA vaccine tested in mice reduces accumulation of both types of toxic proteins associated with Alzheimer’s disease, according to research that scientists say may pave the way to a clinical trial. Highlights A DNA vaccine reduces both harmful proteins associated with Alzheimer’s disease, without the brain swelling caused by earlier antibody treatments. Scientists say

A DNA vaccine for Alzheimer’s moves closer to human trial

A micropeptide molecule that can restore normal heart function: in mice

A micropeptide molecule that reverses structural and functional changes in the heart could be a promising target for gene therapy. Researchers have discovered a micropeptide molecule that can restore normal heart function in mice, according to a study in eLife. The micropeptide works by preventing calcium dysregulation and remodelling of the heart and could be

A micropeptide molecule that can restore normal heart function: in mice

Identifying a gene that helps cells resist West Nile and Zika viruses with CRISPR

UT Southwestern researchers today report the first use of CRISPR genome-wide screening to identify a gene that helps cells resist flavivirus infection. That nasty class of pathogens includes West Nile virus, dengue fever, Zika virus, and yellow fever. In a study published in Nature Microbiology, the team led by Dr. John Schoggins, Assistant Professor of Microbiology, used

Identifying a gene that helps cells resist West Nile and Zika viruses with CRISPR

Halting Duchenne muscular dystrophy progression in dogs with CRISPR

Scientists for the first time have used CRISPR gene editing to halt the progression of Duchenne muscular dystrophy (DMD) in a large mammal, according to a study by UT Southwestern that provides a strong indication that a lifesaving treatment may be in the pipeline. The research published in Science documents unprecedented improvement in the muscle fibers of dogs

Halting Duchenne muscular dystrophy progression in dogs with CRISPR

Cellular housekeeping shows a potential for lifespan and healthspan extension in mammals

Building on two decades of research, investigators at UT Southwestern have determined that “cellular housekeeping” can extend the lifespan and healthspan of mammals. A study jointly led by Drs. Salwa Sebti and Álvaro Fernández, postdoctoral researchers in the Center for Autophagy Research, found that mice with persistently increased levels of autophagy – the process a cell uses

Cellular housekeeping shows a potential for lifespan and healthspan extension in mammals

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QI study demonstrates better outcomes for NICU infants with optimized use of CPAP and surfactant
A study conducted at Parkland Health and Hospital System by neonatologists from UT Southwestern Medical Center showed that optimizing the use of continuous positive airway pressure, or CPAP – the same ...
NIH Grant Funds CARE4Kids Pediatric Concussion Research Study
The National Institute of Neurological Disorders and Stroke has awarded a $10-million grant to a consortium of academic institutions focused on identifying the best diagnostic techniques for ...
Meeting Basic Needs That Affect Medical Outcomes
Services and resources helping people meet needs like home repair, transportation and healthy food often play a major role in medical outcomes. In Texas, life expectancy can vary as much as 30 years, ...
Hospitalizations of pregnant people rose with the delta variant, study shows
The rate of pregnant people hospitalized due to COVID-19 increased with the rise of the delta variant, according to a Dallas-based study by University of Texas–Southwestern Medical Center researchers.
ChemoCentryx Appoints Rita I. Jain, M.D. as Executive Vice President, Chief Medical Officer - Form 8-K
ChemoCentryx Appoints Rita I. Jain, M.D. as Executive Vice President, Chief Medical Officer. Appointment Brings More than 20 Years of Drug Development Experience as Company Launch ...

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In quiet debut, Alzheimer’s drug finds questions, skepticism
The first new Alzheimer’s treatment in more than 20 years was hailed as a breakthrough when regulators approved it more than four months ago, but its rollout has been slowed by questions about its ...
Dallas ISD and UT Southwestern partner to open a new kind of school
Dallas ISD and the UT Southwestern Medical Center (UTSW) together will launch a new transformation school slated to open its doors next fall.
Berke Collects $275,529 For State Senate Campaign
A man who said he had been inside Buds at 5751 Brainerd Road for about two hours came out to his car and found it had been broken into. There was a phone that was dropped in the driver's seat ...
Tenaya Therapeutics to Present Preclinical Data on Its Gene Therapy Programs at the ESGCT 28th Annual Congress
Founded by leading cardiovascular scientists from Gladstone Institutes and the University of Texas Southwestern Medical Center, Tenaya is developing therapies for rare genetic disorders as well as for ...
ChemoCentryx Appoints Rita I. Jain, M.D. as Executive Vice President, Chief Medical Officer
Jain, M.D., as Executive Vice President, Chief Medical ... Island University Hospital followed by a Fellowship in Rheumatology at North Shore University Hospital and a Clinical Research Fellowship at ...