Buck Institute for Research on Aging

The Buck Institute for Research on Aging is the United States’ first independent biomedical research institute devoted solely to research on aging and age-related disease.

Could illness and mortality be predicted by your immune system “clock”

Extending lifespan by 500 percent – in worms

Update: Parabiosis is one of the hottest topics in age research

Older mice who are surgically joined with young mice in order to share a common bloodstream get stronger and healthier, making parabiosis one of the hottest topics in age research. Publishing in Nature Metabolism, researchers from the Buck Institute report that MANF (mesencephalic astrocyte-derived neurotrophic factor) is one of the factors responsible for rejuvenating the transfused older

Update: Parabiosis is one of the hottest topics in age research

Removal of aging cells contributes significantly in delaying the onset of age-related pathologies

A new study, affiliated with UNIST confirms that targeting SnCs could treat age-related degenerative joint disease. A recent study, led by an international team of researchers confirms that targeted removal of senescent cells (SnCs), accumulated in many vertebrate tissues as we age, contribute significantly in delaying the onset of age-related pathologies. This breakthrough research has been led

Removal of aging cells contributes significantly in delaying the onset of age-related pathologies

Stem cells restore long-term vision in mice using regenerative vision therapy

via Glaucoma Research Foundation Buck scientists restore long-term vision in blind mice, making a case for addressing the immune system’s role in rejecting transplanted cells Stem cell therapies hold great promise for restoring function in a variety of degenerative conditions, but one of the logistical hurdles is how to ensure the cells survive in the body

Stem cells restore long-term vision in mice using regenerative vision therapy

Mapping the Genes that Increase Lifespan

Following an exhaustive, ten-year effort, scientists at the Buck Institute for Research on Aging and the University of Washington have identified 238 genes that, when removed, increase the replicative lifespan of S. cerevisiae yeast cells. This is the first time 189 of these genes have been linked to aging. These results provide new genomic targets

Mapping the Genes that Increase Lifespan

Ibuprofen Use Leads to Extended Lifespan in Several Species, Study Shows

A common over-the-counter drug that tackles pain and fever may also hold keys to a longer, healthier life, according to a Texas A&M AgriLife Research scientist. Regular doses of ibuprofen extended the lifespan of multiple species, according to research published in the journal Public Library of Science-Genetics. “We first used baker’s yeast, which is an

Ibuprofen Use Leads to Extended Lifespan in Several Species, Study Shows

Memory loss associated with Alzheimer’s reversed for first time

Small trial from UCLA and Buck Institute succeeds using systems approach to memory disorders Patient one had two years of progressive memory loss. She was considering quitting her job, which involved analyzing data and writing reports, she got disoriented driving, and mixed up the names of her pets. Patient two kept forgetting once familiar faces

Memory loss associated with Alzheimer’s reversed for first time

Altering Community of Gut Bacteria Promotes Health and Increases Lifespan

Our data suggest that we should be able to impact health span and life span quite strongly Scientists at the Buck Institute for Research on Aging have promoted health and increased lifespan in Drosophila by altering the symbiotic, or commensal, relationship between bacteria and the absorptive cells lining the intestine. The research, appearing in the January 16,

Altering Community of Gut Bacteria Promotes Health and Increases Lifespan

Lifespan-Extending Drug Given Late in Life Reverses Age-Related Heart Disease in Mice

Elderly mice suffering from age-related heart disease saw a significant improvement in cardiac function after being treated with the FDA-approved drug rapamycin for just three months. The research, led by a team of scientists at the Buck Institute for Research on Aging, shows how rapamycin impacts mammalian tissues, providing functional insights and possible benefits for

Lifespan-Extending Drug Given Late in Life Reverses Age-Related Heart Disease in Mice

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Buck Institute for Research on Aging Research

Could Getting Rid of Old Cells Help People Live Disease-Free for Longer?
Judith Campisi, a cell biologist at the Buck Institute for Research on Aging in Novato, California, and others have found senescent cells in adult mice, where they participate in wound healing.
The start-ups seeking a cure for old age
Tech billionaires are funding research to help us live longer and healthier lives, but experts warn of an ethical minefield ahead ...
Good hydration linked to healthy aging
"The results suggest that proper hydration may slow down aging and prolong ... and Blood Institute (NHLBI), part of NIH. The study expands on research the scientists published in March 2022 ...
New drugs could turn the clock back on aging — will they work?
Judith Campisi, a cell biologist at the Buck Institute for Research on Aging in Novato, California, and others have found senescent cells in adult mice, where they participate in wound healing.
Could getting rid of old cells turn back the clock on aging?
Judith Campisi, a cell biologist at the Buck Institute for Research on Aging in Novato, California, and others have found senescent cells in adult mice, where they participate in wound healing.

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Buck Institute for Research on Aging Discovery

Joe Buck Opens Up About Having To Call The Horrifying Damar Hamlin Injury On Live TV
NFL sportscaster Joe Buck has discussed the experience of having to outline Damar Hamlin’s horrifying collapse on live television. Buck was calling the game for ESPN alongside his partner Troy ...
GOP Congressman Ken Buck Tells CNN Live He Will No Longer Support McCarthy for Speaker: ‘Stay Tuned’
Rep. Ken Buck (R-CO) told CNN live on air on Wednesday that he will no longer support Kevin McCarthy for House Speaker. Through five balloting rounds over Tuesday and Wednesday, McCarthy has been ...
Joe Buck reflected on how he covered Damar Hamlin's cardiac injury during 'Monday Night Football'
For ESPN’s Monday Night Football announcer Joe Buck, he was tasked with calling the immensely difficult scene to a national audience. And by all accounts, Buck, Troy Aikman and ESPN covered the ...
Damar Hamlin collapse ‘kind of a blur’ for shocked Joe Buck
IN THE middle of the first quarter on ESPN’s “Monday Night Football,” Joe Buck’s call was pretty innocuous. “Here’s [Tee] Higgins … wide open … to ...
'Being Quiet is OK': Joe Buck on Calling Bills' Tragic Damar Hamlin Moment
As the football world continues to process the tragic situation surrounding Buffalo Bills defender Damar Hamlin, the ESPN broadcasting group that aired the scary happening has received unanimous ...