Buck Institute for Research on Aging

The Buck Institute for Research on Aging is the United States’ first independent biomedical research institute devoted solely to research on aging and age-related disease.

Could illness and mortality be predicted by your immune system “clock”

Extending lifespan by 500 percent – in worms

Update: Parabiosis is one of the hottest topics in age research

Older mice who are surgically joined with young mice in order to share a common bloodstream get stronger and healthier, making parabiosis one of the hottest topics in age research. Publishing in Nature Metabolism, researchers from the Buck Institute report that MANF (mesencephalic astrocyte-derived neurotrophic factor) is one of the factors responsible for rejuvenating the transfused older

Update: Parabiosis is one of the hottest topics in age research

Removal of aging cells contributes significantly in delaying the onset of age-related pathologies

A new study, affiliated with UNIST confirms that targeting SnCs could treat age-related degenerative joint disease. A recent study, led by an international team of researchers confirms that targeted removal of senescent cells (SnCs), accumulated in many vertebrate tissues as we age, contribute significantly in delaying the onset of age-related pathologies. This breakthrough research has been led

Removal of aging cells contributes significantly in delaying the onset of age-related pathologies

Stem cells restore long-term vision in mice using regenerative vision therapy

via Glaucoma Research Foundation Buck scientists restore long-term vision in blind mice, making a case for addressing the immune system’s role in rejecting transplanted cells Stem cell therapies hold great promise for restoring function in a variety of degenerative conditions, but one of the logistical hurdles is how to ensure the cells survive in the body

Stem cells restore long-term vision in mice using regenerative vision therapy

Mapping the Genes that Increase Lifespan

Following an exhaustive, ten-year effort, scientists at the Buck Institute for Research on Aging and the University of Washington have identified 238 genes that, when removed, increase the replicative lifespan of S. cerevisiae yeast cells. This is the first time 189 of these genes have been linked to aging. These results provide new genomic targets

Mapping the Genes that Increase Lifespan

Ibuprofen Use Leads to Extended Lifespan in Several Species, Study Shows

A common over-the-counter drug that tackles pain and fever may also hold keys to a longer, healthier life, according to a Texas A&M AgriLife Research scientist. Regular doses of ibuprofen extended the lifespan of multiple species, according to research published in the journal Public Library of Science-Genetics. “We first used baker’s yeast, which is an

Ibuprofen Use Leads to Extended Lifespan in Several Species, Study Shows

Memory loss associated with Alzheimer’s reversed for first time

Small trial from UCLA and Buck Institute succeeds using systems approach to memory disorders Patient one had two years of progressive memory loss. She was considering quitting her job, which involved analyzing data and writing reports, she got disoriented driving, and mixed up the names of her pets. Patient two kept forgetting once familiar faces

Memory loss associated with Alzheimer’s reversed for first time

Altering Community of Gut Bacteria Promotes Health and Increases Lifespan

Our data suggest that we should be able to impact health span and life span quite strongly Scientists at the Buck Institute for Research on Aging have promoted health and increased lifespan in Drosophila by altering the symbiotic, or commensal, relationship between bacteria and the absorptive cells lining the intestine. The research, appearing in the January 16,

Altering Community of Gut Bacteria Promotes Health and Increases Lifespan

Lifespan-Extending Drug Given Late in Life Reverses Age-Related Heart Disease in Mice

Elderly mice suffering from age-related heart disease saw a significant improvement in cardiac function after being treated with the FDA-approved drug rapamycin for just three months. The research, led by a team of scientists at the Buck Institute for Research on Aging, shows how rapamycin impacts mammalian tissues, providing functional insights and possible benefits for

Lifespan-Extending Drug Given Late in Life Reverses Age-Related Heart Disease in Mice

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Buck Institute for Research on Aging Research

Marin anti-aging physicians at odds over Alzheimer’s approaches
on August 22, 2021 at 7:00 pm
Dr. Dale Bredesen and Dr. Dean Ornish — are looking into how to treat the most pernicious and so far incurable disease associated with aging: ...
Nathan Basisty, Ph.D.
on August 19, 2021 at 12:19 pm
In 2015, he joined The Buck Institute for Research on Aging, where he did his postdoctoral fellowship in the labs of Dr. Birgit Schilling and Dr. Judith Campisi. There he developed novel and ...
Stanford-developed biological clock serves as new way to track aging
on August 18, 2021 at 11:11 am
demonstrated researchers at the Stanford School of Medicine in collaboration with the Buck Institute for Aging. Their research was published in Nature Aging in July. The research provides a new ...
Low Serum Cholesterol and Mortality
on August 16, 2021 at 5:00 pm
From the Institute for Health Promotion and Disease Prevention Research, Department of Preventive Medicine (C.I., J.H.D.), and the Atherosclerosis Research Institute, Department of Medicine (J.H.D.), ...
Buck Institute study illuminates age-related inflammation
on August 7, 2021 at 5:11 pm
Scientists at the Buck Institute for Research on Aging in Novato and Stanford University have found a method to more accurately determine biological age by measuring age-related, chronic inflammation ...

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Buck Institute for Research on Aging Research

Buck Institute study illuminates age-related inflammation - Marin Independent Journal
August 7, 2021
Marin anti-aging physicians at odds over Alzheimer’s approaches - Marin Independent Journal
August 22, 2021
Stanford-developed biological clock serves as new way to track aging - The Stanford Daily
August 18, 2021
Science of Aging is Focus of New Bakar Research Institute - UCSF News Services
February 10, 2021
Q&A with incoming Buck Institute Chief Scientific Officer Malene Hansen - San Francisco Business Times - San Francisco Business Times
January 21, 2021

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Buck Institute for Research on Aging Discovery

Keys to better aging may lie in red blood cells
on August 19, 2021 at 5:00 pm
Still, other research has shown that modern women who ... August 17, 2021 • Your superhero is hairless, buck-toothed and weighs up to two ounces. Sure, he may not sound like much — or look ...
A New Approach to Curing HIV
on August 17, 2021 at 5:13 pm
The group, known as the HIV Obstruction by Programmed Epigenetics (HOPE) Collaboratory, will be led by researchers at Gladstone Institutes, Scripps Research ... the Gladstone Institute of Virology ...
A new approach to curing HIV
on August 17, 2021 at 9:34 am
“Bringing together this diverse group of people with expertise across various disciplines is what will really drive the discovery ... Verdin from Buck Institute for Research on Aging; Betty ...
Interview With Dr. Wang Jian
on August 11, 2021 at 7:27 am
And few people know that some of these entrepreneurs started companies that act as global open research platforms that assisted in the discovery ... institute dedicated to the study of health and ...
AFAR 2021 Irving S. Wright Award: Malene Hansen, PhD (IMAGE)
on August 6, 2021 at 11:52 am
Dr. Hansen is the Chief Scientific Officer and a Professor at the Buck Institute for Research on Aging, Novato, CA, as well as a Professor at Sanford Burnham Prebys Medical Discovery Institute ...