Salk Institute for Biological Studies

The Salk Institute for Biological Studies is an independent, non-profit, scientific research institute located in La Jolla, California.

Can a fast and portable test simultaneously detect and sequence SARS-CoV-2, influenza and other viruses?

Using the science of perception to keep innocent people out of jail

Living longer by eating less?

A combination of two previously studied osteoarthritis drugs reverses arthritis in rats

Can these experimental drugs reverse broader aging in humans as they appear to have done in mice?

Salk researchers show how two experimental Alzheimer’s drugs protect the brains of mice from other aspects of aging In mouse models of Alzheimer’s disease, the investigational drug candidates known as CMS121 and J147 improve memory and slow the degeneration of brain cells. Now, Salk researchers have shown how these compounds can also slow aging in

Can these experimental drugs reverse broader aging in humans as they appear to have done in mice?

Discovered: A gene that determines whether roots grow deep or shallow in the soil

Salk team’s finding will advance initiative to reduce atmospheric carbon through plants Hidden underground networks of plant roots snake through the earth foraging for nutrients and water, similar to a worm searching for food. Yet, the genetic and molecular mechanisms that govern which parts of the soil roots explore remain largely unknown. Now, Salk Institute

Discovered: A gene that determines whether roots grow deep or shallow in the soil

A new CRISPR-Cas9 therapy can suppress aging, enhance health and extend life span in mice

Putting the brakes on aging Aging is a leading risk factor for a number of debilitating conditions, including heart disease, cancer and Alzheimer’s disease, to name a few. This makes the need for anti-aging therapies all the more urgent. Now, Salk Institute researchers have developed a new gene therapy to help decelerate the aging process.

A new CRISPR-Cas9 therapy can suppress aging, enhance health and extend life span in mice

New methods to identify Alzheimer’s drug candidates that have anti-aging properties

Salk research focuses on the development of compounds that may protect against the diseases of aging, such as Alzheimer’s Old age is the greatest risk factor for many diseases, including Alzheimer’s disease (AD) and cancer. Geroprotectors are a recently identified class of anti-aging compounds. New Salk research has now identified a unique subclass of these

New methods to identify Alzheimer’s drug candidates that have anti-aging properties

Turning open wounds into skin through the alchemy of healing

Salk scientists develop new technique to heal large ulcers by reprogramming wound cells into skin cells Plastic surgery to treat large cutaneous ulcers, including those seen in people with severe burns, bedsores or chronic diseases such as diabetes, may someday be a thing of the past. Scientists at the Salk Institute have developed a technique

Turning open wounds into skin through the alchemy of healing

Single injection treats hemophilia B for life, in proof-of-concept study

The Salk approach, tested in a mouse model, points to cheaper and more effective treatments for humans For most people with hemophilia B, whose bodies can’t properly form blood clots, constant injections to replenish their clotting factors are a way of life. But now, Salk researchers have demonstrated in mice that hemophilia B can be

Single injection treats hemophilia B for life, in proof-of-concept study

Many forensic methods have never been scientifically validated – a major issue

MANY FORENSIC METHODS HAVE NEVER BEEN SCIENTIFICALLY VALIDATED, SCIENTISTS NOTE IN EDITORIAL Many of the “forensic science” methods commonly used in criminal cases and portrayed in popular police TV dramas have never been scientifically validated and may lead to unjust verdicts, according to an editorial in this week’s Proceedings of the National Academy of Sciences. The authors

Many forensic methods have never been scientifically validated – a major issue

Drugs for obesity might come from a molecule that gives energy-burning brown fat its identity

A protein found in brown fat, but not typical white fat, is key to how the energy-burning brown fat cells function While most fat cells in the human body store energy, everyone has a small subset of brown fat cells that do the opposite—burn energy and generate heat. Now, Salk researchers have discovered how the

Drugs for obesity might come from a molecule that gives energy-burning brown fat its identity

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Salk Institute for Biological Studies Research

Researchers Reveal How Killer T Cells Are Blocked from Fighting Cancer Cells
on June 11, 2021 at 5:00 am
A new study by scientists at the Salk Institute demonstrates how "bad fats" hinder killer T cells from fighting cancer cells.
Research advances one step closer to stem cell therapy for type 1 diabetes
on June 6, 2021 at 9:00 pm
Scientists at the Salk Institute are developing a promising approach for treating type 1 diabetes by using stem cells to create insulin-producing cells (called beta cells) that could replace ...
New study will help design better antibodies for potential treatments
on June 2, 2021 at 9:08 pm
Scientists are harnessing hard X-rays in the fight against cancer. A team of researchers, in conjunction with the U.S. Department of Energy's (DOE) Argonne National Laboratory, has used ultrabright ...
Advanced Photon Source helps reveal how antibodies bind a molecule linked to cancer
on June 2, 2021 at 1:00 pm
A team of researchers, in conjunction with the U.S. Department of Energy's (DOE) Argonne National Laboratory, has used ultrabright X-ray light to determine how specific types of antibodies can tell ...
Man-monkey hybrid sparks fears of ‘Frankenstein’ creatures
on June 2, 2021 at 11:34 am
Researchers conducting human-animal hybrid experiments struck fear into federal lawmakers worried that nightmare scenarios of Frankenstein creatures have become a reality.

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Salk Institute for Biological Studies Research

Opinion: Ready for this pandemic to end? Here are three things we should all be doing. - The San Diego Union-Tribune
May 13, 2021
New study shows how to boost muscle regeneration and rebuild tissue - EurekAlert
May 25, 2021
'Bad fat' suppresses killer T cells from attacking cancer - EurekAlert
June 10, 2021
New study will help design better antibodies for potential treatments - News-Medical.Net
June 3, 2021
BioSpace Movers & Shakers, June 11 – PharmaLive - PharmaLive
June 11, 2021

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Salk Institute for Biological Studies Discovery

'Bad fat' suppresses killer T cells from attacking cancer
on June 9, 2021 at 9:00 pm
Salk researchers have identified how tumors cause immune cells to lose their ability to fight cancer, by producing harmful fats the energy-hungry immune cells ingest, impairing their functionality.
From the Archives: Francis Crick, born 105 years ago, spent decades in La Jolla
on June 8, 2021 at 3:00 pm
Francis Crick, a Nobel Prize winner for his role in discovering the structure of DNA, was born in Norhampton, England, on this day in 1916.
n-Lorem Foundation Appoints Claire Grezemkovsky as Director of Philanthropy
on June 7, 2021 at 5:03 am
Lorem Foundation, a nonprofit organization providing the ultra-rare disease patients with free, lifetime supplies of individualized RNA-targeted medicines, today announced the appointment of Claire ...
Coronavirus: Kiwi anti-vax group Voices for Freedom accused of channelling the 'pandemic's wrongest man' in latest claims
on June 4, 2021 at 3:35 pm
Kiwi scientists are dismissing new claims from a group opposed to the COVID-19 vaccine rollout, that it can release deadly proteins into the blood - saying they've misread the paper, or are just ...
New study will help design better antibodies for potential treatments
on June 2, 2021 at 9:08 pm
Scientists are harnessing hard X-rays in the fight against cancer. A team of researchers, in conjunction with the U.S. Department of Energy's (DOE) Argonne National Laboratory, has used ultrabright ...