Wistar Institute

The Wistar Institute is an international leader in biomedical science, with special expertise in oncology, immunology, infectious disease and vaccine research

Could SARS-CoV-2 transmission be reduced by chewing gum?

A new class of antibiotics can drug-resistant bacterial pathogens with provoking immune response for combating antimicrobial resistance

Precise activation and tracking of cancer treatment with a new compound is possible

Researchers at The Wistar Institute and the University of South Florida have advanced a novel compound that specifically targets the endoplasmic reticulum (ER) stress response that is frequently hyperactivated in cancer and promotes survival of cancer cells during stressful conditions. The new compound has unique chemical properties that allow for precise activation and can be

Precise activation and tracking of cancer treatment with a new compound is possible

Fate of Independent Research Institutes Hangs in the Budgetary Balance

A decade of neglecting the National Institutes of Health budget has left a sector of science scrabbling to survive I am a mass murderer of squid. I have cut off more Loligo pealei heads than you, and watched those heads writhe around in a bucket for a good three or four minutes post-decapitation—all in the name of

Fate of Independent Research Institutes Hangs in the Budgetary Balance

Findings Offer Alternative Approach to Creating a Universal Influenza Vaccine

Since Prior Flu Exposure Dictates Your Future Immune Response, New Vaccine Regiments Can Be Rationally Developed, Researchers Say A team of scientists, led by researchers at The Wistar Institute, has determined that it might be possible to stimulate the immune system against multiple strains of influenza virus by sequentially vaccinating individuals with distinct influenza strains

Findings Offer Alternative Approach to Creating a Universal Influenza Vaccine

Case Closed: A Fluky Finding Raises Hopes for Mending Wounds

Image via Wikipedia An amazing example of tissue regeneration in mice might lead to treatments that promote wound healing in humans–but it almost went unnoticed Ellen Heber-Katz, a scientist at The Wistar Institute in Philadelphia, used to study autoimmunity—that was until she noticed something strange in the mice she was using to model lupus: The

Case Closed: A Fluky Finding Raises Hopes for Mending Wounds

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Wistar Institute Research

Wistar Institute announces $75 million five-year plan focused on discovery and education
The Wistar Institute’s $75 million five-year plan will focus on driving breakthroughs in cancer, immunology, and therapeutics, as well as educating the next generation of scientists.
Researchers Uncover Protein Involved in Senescence and Tissue Aging
Researchers at the Wistar Institute sought to better understand ... implications in strategies to promote healthy aging. The research team’s findings center around a protein called ADAR1.
Researchers Uncover Protein Involved in Senescence and Tissue Aging
Researchers say that ADAR1, a protein involved in RNA editing, is now also revealed in senescence and its implications in tissue aging.
CFO of the Year Awards 2022: Joseph Trainor, The Wistar Institute
The Wistar Institute doesn’t measure its finances like many other organizations. Rather, the Philadelphia nonprofit biomedical research institution – which specializes in cancer, immunology ...
Wistar scientists reveal a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence
Aging and age-related disorders pose a complex challenge to the biomedical research community. To better understand how senescence is regulated is of high significance to promote healthy aging and ...

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Wistar Institute Research

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Wistar Institute Discovery

Wistar Institute announces $75 million five-year plan focused on discovery and education
The Wistar Institute’s $75 million five-year plan will focus on driving breakthroughs in cancer, immunology, and therapeutics, as well as educating the next generation of scientists.
GV20 Therapeutics Announces Appointment of Three Advisers
GV20 Therapeutics, a biopharmaceutical company using cutting-edge genomics and artificial intelligence approaches to discover next-generation cancer therapeutics, announced the appointment of three ...
Researchers Uncover Protein Involved in Senescence and Tissue Aging
Researchers at the Wistar Institute sought to better understand how senescence is regulated and its high significance in promoting healthy aging and treating age-associated disorders. The ...
Scientists reveal new function of enzyme ADAR1 linking it to age-related diseases via a role independent of RNA-editing during aging
Scientists have revealed a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence and its potential implications in tissue aging.
Collaboration Advances DNA-delivered Antibodies to Prevent COVID-19
The collaborative team was led by David Weiner, Ph.D., The Wistar Institute executive vice president, director of the Vaccine & Immunotherapy Center, and W.W. Smith Charitable Trust Professor in ...